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Ranitidine or Omez - which is better?

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AND omezand ranitidine equally frequently used in clinical practice for the treatment of diseases of the digestive system, or otherwise associated with increased gastric acid secretion. Moreover, some experts prefer the first drug and the other - the second. Is there any fundamental differences in their application or everything is the result of the popular schemes today "doctor-maker", allowing to receive a significant premium to the current salary? What is still to buy in the drugstore: Omeprazole or Ranitidine? How not to be deceived and do not hurt yourself in favor of incompetent professionals? These are the questions we try to answer in this article.

As the stomach produces hydrochloric acid is?

In order to understand that it is better to use ranitidine or Omez to treat similar diseases, it is necessary to apply the fundamental knowledge of the medical field and learn how the process of production of hydrochloric acid stomach.

Thus, hydrochloric acid is produced in the stomach cavity special parietal cells located in the interior of fundic glands. This occurs, as influenced by the nervous system, potassium hydrogen ions and protons, and with the participation of bioactive substances: histamine, gastrin - gastric acidity increase somatostatin and - blocks the production of hydrochloric acid in three main phase:

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  • Cephalic phase. Actually, the beginning of secretion factor in its start-up is to excite the nervous system view, taste or smell of food. Phase begins long before its entering into the stomach and used to prepare the organ to the digestion process;
  • Gastric phase. The most significant phase factor is its start getting food into the gastric cavity with subsequent stretching. Under the influence of the action of its walls mechanoreceptors starts generation gastrin G-cells and histamine ECL-cells, which, in fact, leads to the production of hydrochloric acid;
  • Intestinal phase. The final begins when the food in contact duodenum, which leads to the development and subsequent blockage of somatostatin secretion of hydrochloric acid.

Pay attention to the mechanism of action

The result of the application of both drugs is to reduce the acidity of gastric juice, which simultaneously reduces acid damaging effect on the wall bodies of various gastrointestinal, and eliminates associated with this, an unpleasant symptoms. However, they operate differently: Ranitidine stops the output of histamine and Omez - release of hydrogen protons. In both cases, the secretion of hydrochloric acid is not blocked completely, and a decrease of its volume, that is good to maintain a normal body health.

See also: Full instructions on the administration of ranitidine

At first glance, it may seem that Ranitidine Omez and can be used in all cases where there is a hypersecretion of gastric symptoms. But, bearing in mind that histamine exerts a significant influence on the process, and prolonged his absence could result described earlier, at the end of end, to the corresponding regions of atrophy of the mucosa and development of functional digestive disorders, drugs of choice for long-term use becomes Omez. In those cases where it is necessary to achieve a more pronounced treatment effect in a shorter time - Ranitidine should be selected.

See also: Full instructions for use omez

The main advantages and disadvantages of individual preparations

But it is not only essential (as it turned out) the differences in the mechanism of action of drugs that can prompt choose - Omez or ranitidine, because each of them is both unique advantages and disadvantages.

Ranitidine advantages:

  • The preparation of domestic production, whose effectiveness is checked by decades of clinical practice;
  • Despite numerous statements about its ineffectiveness, in comparison with similar products, Ranitidine equally well manifest itself in all applications;
  • Low cost, availability of all categories of the population;
  • Rapid achievement of therapeutic effect in sufficient quantities;
  • Complete absence of a teratogenic and carcinogenic effects, proved by numerous studies using laboratory animals.

Disadvantages Ranitidine:

  • Inability to use the drug in patients suffering from diseases of the liver and / or kidney disease, during pregnancy and in children under 12 years;
  • The risk of disorders of the liver and lymph formation during prolonged use;
  • The possibility of side effects in the form of dizziness, which may temporarily exclude the possibility of transport management, or active employment activities.

The main advantages of omez before ranitidine are:

  • The ability of the drug in patients with renal insufficiency no dose correction;
  • Production at a more perfect and modern equipment;
  • The possibility of using the drug for a long time without the risk of atrophy of the gastric mucosa.

The main disadvantages omez:

  • Inability to use in pregnant women and nursing mothers;
  • Widespread low quality of the formulation;
  • Lack of experience in the use of national clinical practice;
  • The possibility of buying counterfeit products.

Clinical study of using omez instead Ranitidine

  • Ranitidine may be replaced omez in those cases where, for some reason, the first drug is not well tolerated by patients or often causes side effects;
  • Application omez necessary in case of kidney disorders, including their lack of varying severity;
  • Omez is the drug of choice for elderly patients;
  • Omez should be appointed if there is need for constant control of gastric acidity for a long time;
  • Ranitidine may be employed instead Omez and when stopped by a pathological process, and the need to achieve a strong therapeutic action disappears.

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