One person appointed in diabetes Diabeton, and another - Metformin. And once people start to find out what is better: Metformin or Diabeton, because the patient wants to stabilize blood glucose levels and avoid unwanted side effects. But before choosing the best drug, should familiarize themselves with the attached annotation to drugs.
General information about medicines
Despite the fact that Metformin is an analog Diabeton, there are differences between the drugs.
Structure and mechanism of action
The active substance Metformin - metformin hydrochloride, which is sugars correction taking twice per day.
Under the influence of the drug in the body is as follows:
- are utilized in excess blood sugar;
- sugars slows absorption through the intestinal mucosa;
- enhanced insulin sensitivity.
When receiving Matformina improve metabolic glucose metabolism and decreased plasma concentration of low density lipids.
Due to improved sugar and fat metabolism to normal glucose levels and reduced body weight.
Gliclazide, which is part of Diabeton MW, operates differently:
- lowers plasma glucose;
- increases insulin synthesis;
- increases sensitivity to insulin hormone.
The amount of insulin in the blood increases during the consumption of food and this contributes to the full response splitting and assimilation of sugars.
Diabeton has antioxidant and antithrombotic properties. Under the influence of the drug is improved cellular metabolism and increased blood flow. Medicine drink once a day, in the morning.
Indications for use
Diabeton and Metformin prescribed taking in type 2 diabetes when at normal or slightly reduced growth hormone secretion is reduced susceptibility to insulin.
But Metformin, unlike Diabeton are used for correction of weight caused by a metabolic disorder.
Contraindications
Metformin should not be taken in the following cases:
- intolerance to medication components;
- ketosis or acidosis;
- komatozonoe state;
- tissue hypoxia (acute and chronic);
- functional disorders of the liver;
- alcohol consumption;
- Pregnancy and lactation;
- children under 10 years.
Short-term ban on the use of the drug is associated with the introduction of iodine in the body cells before carrying out X-ray or radionuclide study. 2 days before the test with iodine treatment metformin cancel and resume after a couple of days after the procedure.
injecting insulin use is not a contraindication for the use of metformin.
Diabeton not be used under the following conditions:
- allergic to gliclazide or auxiliary components tablets;
- childbearing;
- lactation;
- insulin;
- ketoacidosis and diabetic coma;
- kidney or liver dysfunction;
- age 18 years.
Can not assign Diabeton patients who take miconazole, medications or phenylbutazone with dinazolom.
But, despite the fact that the difference between the metformin and Diabeton have both good drug helps with glucose metabolism correction, caused by a decrease in insulin sensitivity.
Comparative characteristics
After reviewing the characteristics of drugs can be compared and Metformin Diabeton.
similarity
First, consider the similarity of the drugs:
- release tablets;
- have similar readings;
- It helps to normalize blood glucose levels.
Drugs are non-structural analogs and, unless otherwise stated, may be taken instead Diabeton Metformin.
Difference
If you compare the products, you will notice a number of differences:
- Dosage. Diabeton tablet contains 60 mg of active ingredient, and Metformin - 500 mg. When replacing one drug to another recalculation is required therapeutic dose.
- Mechanism of action. Diabeton enhances insulin secretion, and metformin has no effect on the development of pancreatic hormone.
- Age restrictions. Diabeton disabled children and Metformin allowed the age of ten.
- Compatible with insuinoterapiey. Diabeton not be prescribed to patients receiving insulin injections.
- Ease of use. Compared with metformin, which is taken twice a day, a single morning dose Diabeton more convenient.
Between the drugs, despite the same indications and the therapeutic effect, a lot of differences. Choosing between Diabeton and metformin therapy in the appointment of a diabetic, the doctor takes into account not only the nature of the breach of the glucose metabolism, but also the overall health of the patient.
Can I drink together
Endocrinologists are often prescribed to drink at the same time Diabeton and Metformin. Medications have different composition and combine well with each other. But to achieve the desired therapeutic action, drugs need to drink right:
- Diabeton taken once in the morning;
- Metformin is divided into 2 doses and after meal or during meal, glass of water.
Diabeton enhance the synthesis of the hormone insulin and reduce blood sugar. Metformin helps to dispose of excess glucose and swept the absorption of sugars in the intestine. Taking Diabeton with metformin, it is possible quickly to reduce sugar levels and normalize glucose metabolism.
Is it possible to replace drugs
Despite the fact that drugs are analogues, alone replacement drugs can not be performed: medications have different dosage and recalculation is required when replacing the received amount medications.
In addition, the replacement is not always possible due to the presence of contraindications and different mechanism of action. When selecting analogue, doctors first prescribe drugs from the same group, and then to pick up medications differ greatly in composition.
In the selection of substitute Diabeton first patient propishut Mannino, also referred to as sulfonylureas. Metformil will be given only in case of intolerance of medicines from the group of sulfonylureas.
The drugs can be replaced with one another, but make it a doctor, taking into account the contraindications and the risk of possible side effects.
What's better
This question is impossible to give a definite answer.
The choice depends on many factors:
- with a slight decrease insulin synthesis Diabeton better choose which slightly raise the secretory activity of the pancreas;
- opt Metformin is in the treatment of diabetes in a child;
- if necessary additions insulin antihyperglycemic tablet receiving means select Metformin;
- if necessary, in addition to reducing sugar, remove free radicals from cells, it is necessary to use Diabeton with antioxidant qualities.
Which one is better medicines: Diabeton or Metformin - an endocrinologist decides after examination of the patient. To pick their own means for correcting the level of glucose in diabetes is forbidden: the wrong choice of means or an error in the therapeutic dose can cause serious complications.
sources:
Vidal: https://www.vidal.ru/drugs/metformin-5
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = ac45cb5c-4394-42ca-8479-a60a7a67e0b0 & t =
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