Useful For Preparations
The Best Analogy Metformin

TOP 14 analogues of Metformin: A review of drugs being replaced

click fraud protection

characteristics of drugs

Metformin belongs to hypoglycemic drugs. Means can be bought in the form of a tablet form (500 mg, 850 mg, 1000 mg). The cost of drugs is 93 - 465 rubles. The active ingredient of the drug is metformin hydrochloride.

Well medicament reduces gluconeogenesis, reduce fatty acid synthesis, inhibits oxidation of fat molecules. Drugs can increase receptor sensitivity to insulin at the periphery. Means faster utilization of glucose molecules. The drug has no effect on the blood concentration of insulin, but may change hemodynamic insulin molecules.

The drug increases the formation of glycogen. Against the background of the drug increases capacity glucose transporter molecules decreases the permeation rate of glucose through the intestinal wall. Number of lipid molecules is reduced. body weight decreased or remained stable.

According to the instructions, the medicine used for the treatment of diabetic patients. The drug is used, if not help diet and exercise therapy. Adult agent can be used with other drugs that reduce the sugar in the bloodstream, as well as with insulin. Children Metformin is prescribed to 10 years of age as the only hypoglycemic drug or combine it with the administration of insulin.

insta story viewer

Restrictions to the appointment of the drug:

  • metabolic acidosis;
  • coma, predkomatoznoe state ketoacidosis in diabetics;
  • renal dysfunction;
  • severe infectious pathology;
  • hypoxic conditions (heart disease, changes in respiratory function);
  • intravenous iodinated agents for X-ray examination and computerized tomography;
  • poisoning spirituous beverages;
  • allergic to Metformin.

The drug is carefully used in elderly patients over the age of 60 who are engaged in heavy physical labor (high probability of lactic acidosis). With care prescribe Metformin nursing mothers and patients 10-12 years of age. Gently apply the medicine in patients with kidney disease.

Action Metformin is not fully known when used in pregnant patients. There is evidence that the drug does not increase the risk of malformations in the child. Upon the occurrence of pregnancy, or planning it is better to cancel a medicine, not to get a negative effect on the mother and baby.

The medicine should not be given together with the iodine-containing drugs. It is not necessary to combine metformin with alcohol. Not recommended simultaneous use of the drug with a glucocorticosteroid hormone, diuretic drugs danazol, chlorpromazine, a drug on the pressure, β2-agonists, and other means.

The drug should not be used alone, as it has a large number of undesirable effects. In applying the drug possible lactic acidosis, megaloblastic anemia (decreased suction vit. AT 12). Patients marked change in taste sensation, dyspepsia, allergy (skin reactions), elevated liver enzymes, hepatitis development.

When using high doses of medication possible lactic acidosis. The patient is observed respiratory disorders drowsiness, indigestion, pressure reduction and body temperature, reducing the frequency of rhythm. There may be muscle cramps and impaired consciousness.

When the symptoms of lactic acidosis patient needed urgent hospitalization. This allows you to quickly arrest the symptoms of lactic acidosis. For removal overdose symptoms hemodialysis.

Analogs medicament

Metformin has structural and non-structural analogues. Metformin structural alternatives have also therapeutic substance. They are called generic or synonymous. Non-structural analogs may differ in composition, but have a similar effect on the body.

Similar to metformin is often used if Metformin is relatively expensive for the patient, or the patient is not suitable. If the reason for the replacement of the drug - the price, it is best to look for structural analogs. If the medicine does not fit, the most prescribed non-structural analogue.

Forms similar means

Number of similar drugs is big enough. Many of them have a similar composition. the cost of drugs can vary, but only slightly.

Metformin has analogs (structural):

Russian analogues

Imported analogues Metformin

  • Formetin;
  • Novoformin;
  • Metformin-Richter;
  • Merifatin;
  • Gliformin;
  • Bagomet.
  • Formin Pliva;
  • Sofamet;
  • Siofor;
  • Nova Met;
  • Metformin-Teva;
  • Metformin Zentiva;
  • Metfogamma;
  • Glucophage.

For similar analogues Metformin belongs Reduxine Met. It has a slightly different composition. Its often used for obesity therapy, especially in patients with diabetes and prediabetes.

Analogues made in Russia

1. Bagomet

Russian substitute for the drug Metformin - it Bagomet. The active component of the drug is metformin hydrochloride. It reduces the absorption of glucose molecules in intestinal tube, a decrease in gluconeogenesis in liver tissue.

The drug does not increase the degree of insulin does not cause hypoglycemia. Analogue is in the form of tablets (500 mg, 750 mg, 850 mg, 1000 mg). The limitations and side effects of the drug at the same as that of the Metformin.

The price of an analogue is 38 - 428 rubles. He's a bit cheaper than metformin.

2. Formetin

Metformin is a cheaper analog of Formetin. The drug has a composition of metformin hydrochloride. The drug is manufactured as a tablet form (500 mg, 750 mg, 850 mg, 1000 mg). analog value is - 57-229 rubles (some pharmacy it can be a bit expensive).

Pharmacokinetics and adverse effects from medication are the same as that of metformin. The drug is not prescribed to pregnant patient and a child under 18 years of age. During lactation analogue I use very carefully.

3. Novoformin

Similarly, means is Novoformin. The drug can be available in pharmacies as a tablet form (500 mg, 850 mg). The price of a medicine is 49-153 rubles. Therapeutic agent components is metformin hydrochloride. The drug has similar limitations. The analogy is not used in pregnant and lactating patients. Children drug is prescribed only when indicated.

4. Metformin-Richter

Metformin-Richter - an analogue, which is produced in Russia. The drug is in the form of tablets (500 mg, 850 mg, 1000 mg). Drug component is the same as and Metformin. The drug is not used during gestation. Carefully appointed agent in children 10-12 years of age. You can not use an analogue of a child under 10 years of age and nursing mothers. The price of the drug is 89-186 rubles.

5. Merifatin

Metformin is considered good analogue Merifatin. He, too, is available in our country. The drug can be bought in the form of a tablet form (500 mg, 850 mg, 1000 mg). Medicinal ingredient is metformin hydrochloride. Medicine is not used in time of gestation and lactation. Permitted use of the drug in pediatric practice. Carefully prescribed medication to elderly patients. analog value is 169-283 rubles.

6. Gliformin

Metformin can replace Gliforminom. The drug is in the form of tablets (250 mg, 500 mg, 850 mg, 1000 mg). The medicine does not differ from Metformin Pharmacokinetic, limitations and undesirable effects. The facility has a value of 93-216 rubles. The drug can be a bit expensive.

foreign drugs

7. Siofor

More famous foreign counterparts considered Siofor. Means produces Germany. The drug can be bought in the form of a tablet form (500 mg, 850 mg, 1000 mg). Its gently used in pediatric practice (10-12 years of age). Children 10-18 years of age drug is indicated as monotherapy or in combination with insulin.

Insulin dosage is chosen by the level of glucose in the bloodstream. Child under the age of 10 years shows the drug. You can not use an analog in pregnant patients and nursing mothers. Carefully appointed agent in patients older than 60 years of age. Siofor price is 212 - 477 rubles.

8. Nova Met

Allowed to drink instead of metformin Nova Met. Swiss analogue. The drug is sold in pharmacies paragraphs in tablet form (500 mg, 850 mg, 1000 mg). Curative component is an analogue of metformin hydrochloride. The tool can be used in patients from 10 years of age. Pregnant and nursing patients the drug is not shown.

9. formin Pliva

Formin Pliva - this is a foreign counterpart. The manufacturer of the drug is considered to be Germany, representative - Israel. The drug is available as a tablet form (850, 1000 mg). Dosages analog large, so it is not used in pediatric practice. The drug is not used during gestation and lactation. Analog can not be given to patients with kidney disease.

10. Glyukofazh

Metformin is an analogue of Glucophage.It can produce, Germany, Russia and France. The drug is sold in tablet form (500 mg, 750 mg, 850 mg, 1000 mg). It means not indicated for use in pediatric practice, since the drug in children has been studied enough.

Accurately prescribe medication in patients with renal insufficiency function when creatinine clearance of 45-59 ml per minute. Allowed gently used analogue in nursing patients and those over the age of 60, but only on the testimony. The cost of the drug is 107 - 729 rubles.

11. Sofamet

Sofamet - a Bulgarian analogue. It also contains metformin. The drug is produced in tablet form (850 mg). Cost analog is from 100 rubles. The drug is allowed for use by a child 10 letnegov age. Means not shown in severe liver damage, kidney damage. Gently use the drug in patients over 60 years of age. The analogy is not administered during gestation and lactation, since it is not fully understood in this patient group.

12. Teva metformin

Metformin-Teva - is an Israeli substitute Metformin. The drug can be purchased in a pharmacy tablet form (500 mg, 850 mg, 1000 mg). The medicine has an average value of - 168- 284 rubles.

Means can not be used in patients under 18 years of age as well as clinical studies in children have been incomplete. Analogue should not be used during gestation and lactation. When planning the preparation of the child you want to cancel, if it was accepted earlier.

13. Metfogamma

Metfogamma - is the German counterpart. The drug is available over the counter in tablet form (500 mg, 850mg, 1000mg). The medicine is indicated for diabetics. it will cost from 134 rubles. The tool is not used in pediatrics. You can not assign an analogue time of gestation and lactation. Not shown in serious pathologies preparation kidney and liver.

14. metformin Zentiva

Metformin is an analogue of Zentiva, which is produced in Slovakia. It is manufactured in tablet form (500 mg, 850 mg, 1000 mg). Means permitted for use in a child older than 10 years of age.

The drug is cautiously prescribed for children 10-12 years of age (as monotherapy or in combination with insulin). Gently used agent for breast-feeding, the average severity of kidney pathologies in elderly patients over age 60 letnengo. During gestation and planning pregnancy drug is not shown. The cost of the drug is 99-212 rubles.

conclusion

Structural analogues of Metformin are almost identical indications and limitations. Some of them may be more release forms. Some drugs can not be used in children because the drug has not been studied in this patient group. During pregnancy and lactation, almost all drugs are prohibited.

Foreign dosage forms have greater value as opposed to domestic, but positive reviews about them. The choice of drugs should carry a doctor, since on the basis of Metformin drugs have a large number of unwanted symptoms and limitations for use. Self-administration of analogues is prohibited in order to avoid complications.

sources:

Vidal: https://www.vidal.ru/drugs/metformin-5
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = ac45cb5c-4394-42ca-8479-a60a7a67e0b0 & t =

Found a bug? Select it and press Ctrl + Enter

  • Share
Paracetamol is a child of 9 years
Useful For Preparations

Paracetamol is a child of 9 years

Dosage paracetamol tablets for 9 years child is generally 200 mg up to 4 times a day. drug dose in this case depends on the age greater than the we...

How long action of paracetamol
Useful For PreparationsThe Duration Of Action Of Paracetamol

How long action of paracetamol

The most popular drug Paracetamol is considered, because it effectively It eliminates the symptoms of diseases such as flu, Colds, chronic inflamma...

How many paracetamol tablets can be drunk at a temperature
Useful For Preparations

How many paracetamol tablets can be drunk at a temperature

All human beings are faced with fever, headache, chills, aches in joints and other symptoms, which causes the common cold, SARS or flu.Therefore, m...