Characteristics mucolytic drug
Ambrobene has a very wide variety of dosage forms. The drug can be purchased at a pharmacy in tablet form, capsules, injection and inhalation solution, syrup. Active agent used in neonatal and pediatric practice, which requires children preparation forms (drops, syrup, solution).
Curative component drug is ambroxol hydrochloride. This component is considered to be a derivative of bromhexine. Ambroxol capable phlegm by breaking bonds in the bronchial mucus. Also, the drug can stimulate the secretory activity of the bronchial mucosa cells. Due to these mechanisms preparation promotes liquefaction of mucus and easier advancement of its bronchial routes. Liquefy the phlegm is easier to identify with the cough reflex.
Ambrobene able to accelerate the production of surfactant. This substance is essential for lung tissue, as does not fallen down the alveoli, alveolar wall supports in good shape. Against the background of the use of the drug is enhanced job type 2 pneumocytes, as well as Clara cells, located in the small bronchi and bronchioles. The cellular structure under the effect of ambroxol increases the formation of surfactant that facilitates respiratory function.
During use of antibacterials ambroxol can increase their concentration, which increases the effectiveness of antibiotic therapy. The concentration of antimicrobials primarily in increased bronchial mucus. This is an advantage for severe bacterial respiratory diseases.
After receiving Ambrobene the active component is absorbed in the digestive tract. Ambroxol is capable to take place in the cerebrospinal fluid, milk woman. The substance can pass through the placenta to the baby. The medicine comes out of the body in the urine.
Indications for use of injectable solution Abmrobene:
- bronchitis, acute and chronic flow;
- pneumonia;
- asthma;
- bronchiectasis;
- production of surfactant in premature babies and newborn infants (with a total treatment).
Form solution is shown to use if the patient can not take oral form of the drug. You can also use the solution to achieve rapid therapeutic action. Injection should be used when non-productive cough, sputum scarce and viscous.
Tablet forms, syrup, oral and inhalation solutions shown in asthma, bronchitis, pneumonia. The medicine may be used with bronchiectasis. Ambrobene (inhaled and oral) is used at trudnoothodyaschey and viscous bronchial mucus.
Restrictions to the appointment Ambrobene:
- gestation period (12 weeks) (for all forms of the drug);
- malabsorption, lactase deficiency (syrup);
- are allergic to components of the medication (for all forms);
- children under 6 years of age (for tablet forms);
- children under 12 years of age (capsule form)
Gently Ambrobene used in violation of the ciliary epithelium, ulcerative lesions of the digestive tract, during gestation (2,3 trimester), lactation. For patients with severe renal pathologies drug administered with long intervals between doses.
Types of cough, the general principles of therapy
More common are 2 main types of cough. Cough can be dry and moist. Dry cough is characterized by the fact that when there is no phlegm. He often caused by stimulation of the cough center. This further enhanced cough before going to bed at night. Dry cough may be bronchitis or pertussis infection, asthma. Also, it may cause some medications for high blood pressure with prolonged use. During the dry cough strongly irritate the bronchial tubes, which provokes a painful feeling in the chest.
Cough can be productive and unproductive. A productive cough is characterized by sufficient amounts of sputum. It has a liquid consistency, good cough. Such cough does not require prescribing cough resolves on its own. Medications may be necessary if the nature of the sputum changes.
Non-productive cough is characterized by the fact that sputum produced little. Also in this form of cough bronchial mucus has a very thick consistency. It is bad comes out of the bronchial tree during the cough reflex.
Cough treatment based on the use of causal and symptomatic therapy. Causal treatment is aimed at eliminating the causes. For drugs etiotropic therapy include antiviral, antibacterial drugs. For the symptomatic treatment of cough medicines include antitussives, mucolytics and expectorants.
Severe bouts of dry cough eliminate cold preparations (Sinekod). Also facilitate the formation of phlegm help expectorant drugs (Mukaltin) and some mucolytics (Ambrobene bromhexine). For the treatment of reproductive cough expectorants and mucolytics recommended drugs.
At what should be used cough medicine
Application Ambrobene when coughing permitted both when dry and when wet cough. When dry cough drug enhances the formation of bronchial mucus. When unproductive cough wet sputum is liquefied and a quick exit from the bronchi.
Get rid of cough using Ambrobene can be both children and adults. Adult patients Ambrobene used in all forms, but most often in the form of inhalation solution and tablet forms. Children appoint inhalation solution Ambrobene. The drug can be used in the form of a syrup, oral solution, tablet forms (children from 6 years of age).
Inhalation form has high efficacy in the treatment of cough, since it does not pass through the blood. for inhalation solution is fed directly into the lumen of the bronchial tree, which speeds up the effect of treatment. The child to use, the best inhalation or oral solution Ambrobene since syrup can cause allergy to fruit flavors. The injectable form for the treatment of cough is less common. It is usually prescribed if the patient can not take oral medication, can not tolerate inhalation.
Use of the drug during the wet cough
In wet cough Ambrobene can drink tablets, syrups, solutions, capsules. The drug can be used for inhalation. In pediatrics solution is used more often, syrup, especially in children under 1 year and preschoolers.
Drink Ambrobene when wet cough for children and adults can be in the following dosages:
Pills |
Syrup |
inhalation solution |
oral solution |
|
|
|
When using the solution for inhalation formulation should be diluted with saline 1: 1. Ready inhalation solution should be preheated to 36,6 ° C. Steam Inhaler is not suitable for inhalation treatments Ambrobene. Better to use a nebulizer.
Adults and adolescents can be applied even Ambrobene capsule 1 capsule once per day. In severe coughing solution is used for injection (in case of impossibility of oral and inhaled forms). The solution shown Ambrobene administered intravenously bolus or infusion. The drug is diluted in nat. solution or Ringer's solution.
dosages:
- kids up to 2 letnegov age - 1 ml twice per day;
- patients 2-6 years of age - 1 ml for three knock;
- patients 6 years of age and older - 2 mL twice or three times per day;
- adult patients - 4 ml twice or three times per day (in severe cough - 8 ml twice or three times per day).
Duration of the wet cough can be different (from 4-5 days to 2 weeks). Ambrobene independently take more than 5 days should not be. Injectable form of the drug is prescribed only by a doctor (usually a hospital).
Therapy dry cough
Ambrobene with dry cough may be used in any form and in the same doses as in the wet cough. Adults can use the inhalation and pills, capsules. Infants, preschool and school children are very well help inhalable solution, syrup, oral solution. Ambrobene administered at the first signs of the disease.
Ambrobene drug to treat a dry cough can be for 4-5 days. If necessary, extend the treatment. Independently take the drug for more than 5 days should not be. Continue therapy is possible only on the doctor's recommendations. If the medicine does not work (the attacks are), then it is better to replace it with an antitussive drug.
conclusion
Ambrobene considered effective. Before using the product it is necessary to clarify the kind of cough. The medicine should not be used alone. Can not be combined with other means of antitussive, expectorant and mucolytic agents. Correct reception Ambrobene well relieves cough, especially when it is used by inhalation.
sources:
Vidal: https://www.vidal.ru/drugs/ambrobene__1523
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 4ce4b6f1-696e-44b0-a7ea-805c6d6df9b5 & t =
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