People suffering from diabetes, endocrinologists recommend for therapeutic purposes to take hypoglycemic agents, such as metformin. In the appointment of a doctor should immediately explain to the patient how long you can take Metformin. If the drug helps control blood sugar levels, the period of treatment is not limited.
The principle of action of the drug
Metformin is used to reduce blood sugar. At the same time taking the drug at the recommended dose does not cause hypoglycaemia. Metformin does not stimulate the production of insulin cells in the pancreas, so the hypoglycemic effect in individuals who do not have diabetes, it does not have.
Active agent enhances glucose utilization body tissues, increases the susceptibility of peripheral insulin receptors. Simultaneously, the process is inhibited glucose production of the liver cells. When receiving Metformin improves lipid metabolism. By its action decreases the concentration of cholesterol, triglycerides, low density lipoproteins.
In order to achieve the desired therapeutic effect, patients should drink Metformin without interruption. The treatment is interrupted or reviewed in cases where there are contraindications to, or a state against the backdrop of regular admission means deteriorates.
Patients reported a positive effect of tablets on patients suffering from obesity. In the treatment they stop gaining weight, some he even begins to decrease gradually. Due to this influence, many are beginning to take Metformin weight loss.
The maximum concentration of the active components is observed after 2.5 hours after ingestion of the tablet. But simultaneous food intake leads to weakening of the retention and absorption process Metformin. Output means advantageously kidney poluvyvoda period of 6.5 hours.
Indications for use
Metformin is practiced in cases where the patient can not normalize carbohydrate metabolism through diet and exercise. They use it for diabetes prevention in patients who have been diagnosed prediabetes and identified additional risk factors specified endocrine disorders, and for treatment.
Even if the pill was appointed as a preventive measure, it is important to go to the end of the recommended therapeutic course. Metformin Treatment for diabetes is not limited in time. If the tool helps monitor the condition, it can be drunk for years.
Assign drink tablets for patients older than 10 years with insulin-dependent type of diabetes. If necessary, it is combined with administration of insulin, adults combination therapy can be administered in which other oral hypoglycemic agents used.
The recommended dose regimen
Prescribe metformin treatment should endocrinologist. He can pick up the correct dosage, depending on the test results and the patient's general condition.
In the absence of individual recommendations doctors recommend to orient the circuit specified in the instructions for use:
- initial dose of 500-850 mg;
- After 1-2 weeks it is corrected, focusing on the results of the analyzes supporting the dosing is considered to be 1500-2000 mg per day;
- the maximum daily amount of metformin - 3000 mg tablet taken in such numbers begin no sooner than a month from the start of treatment.
Metformin is necessary to drink tablets 2-3 times a day. To reduce the likelihood of side effects from the digestive system, doctors are advised to take Metformin time. At first, it is better to drink along with a meal or immediately after a meal.
Patients with prediabetes appoint 1000-1700 mg metformin per day, said dose should be divided into 2 doses. Do not expect words from the doctor that taking Metformin 10 days will have this facility is intended for long-term therapy.
In case of violation of carbohydrate metabolism patients are advised to regularly check blood sugar (fasting and after exercise). Depending on the survey results, the treatment is adjusted. While improving the state endocrinologist may recommend to stop taking the pills.
In identifying impaired glucose tolerance or diabetes treatment confirmation must appoint a physician. If the condition is not critical, then initially we can restrict diet therapy and increased physical activity. With the ineffectiveness of these methods is prescribed Metformin. You need to take pills every day, avoiding interruptions in treatment.
If such therapy can keep diabetes under control, it is not correct. Patients need to understand that the drug will have to take throughout their lives.
sources:
Vidal: https://www.vidal.ru/drugs/metformin-5
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = ac45cb5c-4394-42ca-8479-a60a7a67e0b0 & t =
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