Aktovegin - drug activating metabolism and trophism uluchshauschee that decreases tissue hypoxia and stimulating regeneration. Aktovegin applied intramuscularly, intravenously, orally and topically. For each method of application has a separate dosage form.
Characteristics of drugs
Actovegin used for production of dairy calves blood, from which by dialysis and ultrafiltration prepared deproteinized gemoderivat. It contains amino acids, macro elements, trace elements, fatty acids, oligopeptides and other important physiological component.
After receiving a doctor's appointment to therapy ampoule form of the drug, many are asking whether it is possible to prick Aktovegin intramuscularly or need intravenous infusion. The answer can be made as your doctor or pharmacist, and after reading the leaflet to the drug - a drug used for intramuscular administration.
Aktovegin produced in several dosage forms, injection, ointment, tablet, cream, solution for infusions and gel. This allows each patient to choose the appropriate means perfect.
In particular, injections intramuscularly Actovegin conducted using an injection. It is a clear liquid with a yellowish coloring or completely colorless. formulation is sold in vials of 2, 5 and 10 ml. An effective component in the solution is included in an amount of 40 mg per ml. Thus, 2 ml contained 80 mg gemoderivat, 5 mL - 200 mg, and in 10 ml - 400 mg. Auxiliaries protrudes water for injection and sodium chloride.
Ampoules containing 10 ml is not used for intramuscular administration, since the maximum allowable dose of medication in such cases total 5 ml, and store the contents of the opened ampoule forbidden.
Indications drugs
The drug has a complex mechanism of action, ensuring the diversity of its pharmacological effects, so is used in the treatment of many diseases in different areas of medicine. His appointment is justified, if necessary, to improve the nutrition of body tissues, to increase their resistance to hypoxia, that provides the minimum amount of damage to cells of the body structures in the conditions of oxygen deficiency.
Aktovegin of instructions for intramuscular injection is used for:
- anomalous expansion of cerebral vessels;
- lesions of the retina;
- vascular encephalopathy;
- ischemia and oxygen starvation bodies;
- vascular atherosclerosis;
- ischemic stroke;
- angiopatiyah vessels;
- extensive burns, chemical and thermal nature;
- cerebral insufficiency;
- wounds and bedsores;
- diabetic polyneuropathy;
- frostbite;
- traumatic brain injury;
- radiation and radiation damages the skin and mucous membranes.
How to apply
Depending on the severity of the disease shall be appointed or intramuscular infusion medication. This decision, as well as a dose of the drug is taken by the doctor.
Instructions on how to enter intramuscular injections:
- Before the manipulation should wash your hands thoroughly with soap and water and treat with antiseptic;
- Ampoule before the administration needs a little warm in the hand;
- Holding the vial vertically and achieving light tapping on it to all of the solution was in the lower part, break off the tip of a red dot line;
- The sterile drug gaining syringe, then invert it up and releasing a drop of the solution to assure that all air is released;
- Visually buttock separated into 4 pieces, and the needle is introduced into the upper outer square, pre-treating the skin with an alcohol cotton swab;
- Administered drug slowly;
- After injection, the injection site are clamped or cotton cloth dampened with alcohol.
recommended dose
The injections according to the instructions for use Actovegin It applies 2-5 milliliters per day. Administration can be carried out from 1 to 3 times per day.
The attending physician, on the basis of availability indications, severity of disease and the effectiveness of the treatment can modify the recommended dose in one direction or another. If necessary, drug administration at doses exceeding 5 ml recommended application Actovegin intravenously.
The following doses are usually prescribed:
- When circulatory insufficiency of the brain used for 5 ml medication for 14 days. Further appointed tablet form to support the effect;
- To accelerate the process of regeneration of tissue in wounds, frostbite, and other lesions of the epidermis shown daily injections of 5 ml Actovegin solution. Additionally applicable local forms of the drug - an ointment, cream or gel.
Intramuscular administration is used in the lung and the average severity of diseases, whereas in more severe cases require infusions into the vein.
Precautionary measures
For maximum efficiency and safety in the treatment of drug Aktovegin in injections must adhere to the rules of its use.
Before the beginning of a full-fledged therapy should determine whether you are hypersensitive. For this purpose, for 1-2 minutes 2 ml intramuscularly administered drug. Prolonged administration allows you to monitor the body's response to the medication and the development of anaphylaxis may be time to stop and start the injection of the patient's intensive care unit.
From the foregoing, we have the following rule reception - need to do injections in health-care setting, where you can get emergency help if necessary. If, however, expected to home treatment, then at least the first dose must be entered in a hospital under the supervision of medical staff.
Aktovegin allowed intramuscularly administered at a dose not exceeding 5 mlSince the solution is hypertonic and can provoke an abrupt jump in blood pressure.
It is important to create the most sterile conditions during administration of the drug. Open vial should immediately be used, as in medicine there are no preservatives, which would provide a long-term storage. Therefore, the drug should acquire in vials of volume, which is necessary to prick for 1 time. After storage of unopened vials is prohibited.
Aktovegin should be stored in the refrigerator, so before applying the ampoule should be a little warm in the hands for a more comfortable injection.
The solution with visible sediment or clouded use is prohibited. Contents of the vial should have a yellowish color and transparency.
Actovegin allowed inclusion complex schemes disease treatment since reactions negative interaction with other drugs has not been established. It should be borne in mind that mixing it with other drugs in the same vial or syringe is strictly prohibited. Exception - solutions of sodium chloride and glucose, which are recommended for the preparation of infusion solutions. It is also forbidden to drink alcohol during treatment with the drug.
Side effects
Aktovegin has good portability. The most frequent adverse effect during its treatment are allergic reactions including angioneurotic edema. Much less marked:
- skin redness or pallor;
- dizziness;
- chest pain;
- indigestion;
- increased heart and breathing difficulties;
- general weakness;
- increase in blood pressure;
- sore muscles and joints;
- increased heart rate;
- fever;
- paresthesia;
- asthma attacks.
When any adverse reactions to the use of drug therapy should be discontinued Actovegin and assign symptomatic treatment.
Applying intramuscularly injections Aktovegin keep in mind that it is rather unpleasant and painful procedure. Therefore, it is preferable intravenous drip together with a solution of glucose or sodium chloride.
Contraindications
Aktovegin has a high safety profile, which allows its use in a wide range of patients. However, there are exceptions. Intramuscular injection Actovegin prohibited when:
- hypersensitivity agent components;
- heart failure;
- violations of the outflow of urine;
- pulmonary edema;
- renal diseases.
Use of the drug in special patient groups
According to the instructions, pediatric drug should not be administered due to lack of sufficient number of relevant studies. But in practice, many doctors use Aktovegin to treat infants and children.
Intramuscular injections of funds are not practically used in these patients mean painful procedures. The exceptions are infants with the consequences of fetal hypoxia. But these injections are administered only in a hospital under constant medical supervision.
Pregnant women Aktovegin used with caution, after assessing the possible effects on the fetus. If necessary, means of administration is preferred for such patients to intravenous Early treatment with a further shift in improvement in the intramuscular or reception tablets.
Indications purpose are: the threat of termination of pregnancy, feto-placental insufficiency, placental abruption, Rhesus-conflict, weight gain slowing the fruit or its small motor activity.
Use of the drug during lactation is also allowed, but only if its therapeutic effect on the body of the mother is greater than the potential risk for infants.
In geriatrics, the drug is used quite often. At the same time, judging by the reviews, it is in middle and old age a positive impact Actovegin appears best.
sources:
Vidal: https://www.vidal.ru/drugs/actovegin__35582
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = d7775767-e199-4063-9531-bbe08c17f7c7 & t =
Found a bug? Select it and press Ctrl + Enter
