Amoxiclav - modern antibacterial drug. Has high antimicrobial activity, fights bacteria resistant to the antibiotic penicillin. This feature allows you to use it in different areas. How many Amoxiclav excreted from the body?
Amoxiclav successfully applied in gynecology, urology, surgery, pulmonology.
The high efficiency of the drug due to a combination of two components:
- amoxicillin;
- clavulanic acid.
Excretion from the body of the antibiotic
Amoksiklav excreted mainly by the kidneys in an amount of 10-25% of the dose trapped in the body. After appropriate testing, is present at the output of an inactive penicillanic acid. Clavulanic acid is excreted by the kidneys, gastrointestinal tract, and also at the time of exhalation air.
If one Amoksiklava tablet, the active ingredients are output unchanged during the first hours was adopted. When this amount is 70% of amoxycillin, clavulanic acid - 50%.
Amoksiklava half-life occurs within one hour.
Period of excretion occurs Amoksiklava three hours. Amoksiklav excreted completely through day after application. It all depends on the mode of administration and on the personal characteristics of each individual. The drug is administered intravenously will leave the body than in the form of tablets. Rapid clearance of the drug is due to the fact that the antibiotic does not penetrate into the tissue.
The presence of abnormalities
Period Amoksiklava excretion from the body in people with impaired kidney operation differs. The content of active ingredients is reduced in proportion to reduction in kidney function. The situation extends more pronounced for amoxicillin, since it is eliminated via the kidneys.
If a patient in renal disorders, drug is used in extreme cases. In this situation it is necessary to carefully select the required dosage.
See also: Guide to the preparation Amoxiclav
It is recommended to be used only on a doctor's prescription. During the reception, you need to constantly monitor liver function. With hemodialysis, both components are effectively removed fully.
Why is it important to know the
This information is especially important doctor. The physician evaluates the speed Amoksiklava excretion, degree of damage, while defining the dosage and period of administration.
In some cases, drug therapy performed Amoksiklava complex using several means. Receiving incompatible drugs should be after a time interval which is equal to the amount of time during which the antibiotic is completely eliminated.
This feature is important for people who are planning a child. The antibiotic may adversely affect both the very conception and fetal health. After oral amoxicillin, men should plan conception after one month.
verified Article
Anna Moschovis - family doctor.
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