Amoxiclav - an antibiotic, which under force to effectively fight pathogens. And from what helps Amoxiclav?
Amoxiclav is used to treat a variety of diseases - tonsillitis, bronchitis and many other pathologies of upper respiratory tract and the respiratory system, and well as urinary system, infectious processes of the skin and soft tissues, joints and other diseases of infectious and inflammatory genesis.
Ingredients and dosage form
Amoksiklav consists of two main components - amoxicillin and clavulanic acid, differing in composition and, therefore, by the action on pathogenic microorganisms. That this is the effect of the drug. Also present additional components, namely:
- talc;
- stearic acid;
- various flavoring agents;
- sodium citrate;
- citric acid, and so forth.
Today, such a medicine as Amoxiclav on pharmacy shelves can be found in such dosage forms:
- tablets containing amoxycillin 250, 500 and 875 mg clavulanic acid with 125 mg each of the three tablet forms, respectively;
- powdery substance for the preparation of a slurry;
- powdery substance for solutions for parenteral administration.
Features of therapeutic action
Amoxiclav - a substance that has a wide range of applications and is a member of the group of penicillins. Due to the fact that the composition is clavulanic acid, it offers resistance to the remaining components of the enzyme beta-lactamase, which is produced by pathogenic bacteria. Clavulanate in structure similar to beta-lactam antibiotics, which allows you to fight the bacteria.
The presence of amoxicillin enables Amoksiklava fight anaerobes and various kinds of bacteria.
What pathological conditions will help to cope Amoxiclav?
In any form Amoksiklav indicated for the treatment of diseases of pathological processes:
- airway pathologies, and bronchitis;
- inflammation of the gallbladder;
- erysipelas;
- meningitis;
- sepsis;
- abscesses;
- infections of the skin and many others
Also Amoxiclav take to prevent postoperative complications.
Contraindications
Using Amoksiklav drug contraindicated with these pathologies:
- when diagnosing the patient's disease or hepatitis gospel, which progresses on the background use of drugs penicillin group;
- with mononucleosis infectious origin;
- patient with hypersensitivity to preparations of penicillin groups and other components that are part Amoksiklava;
- if the patient lymphocytic leukemia.
Also with extreme caution and under close supervision of a physician should be taken Amoxiclav people have diagnosed pseudomembranous colitis, and hepatic or renal dysfunction failure.
Amoxiclav accepted for the treatment of diseases during pregnancy and breast-feeding only after the treating specialist and exclusively on an individual basis.
How to treat Amoksiklava?
According to the instructions to the drug, Amoxiclav in the form of tablets prescribed to adults and children over the age of 12 years.
For preparation of a solution for intravenous administration for dosage 600 mg active substance is added thereto 10 ml of water for injections, for the dosage of 1200 mg - respectively 20 ml. Fluid is injected slowly, over 3-4 minutes. To prepare the solution for drip infusion preparation after dissolution in 10 ml (20 ml), made up to 50 ml (100 ml) and administered intravenously during 30-40 minutes.
When the disease is mild to moderate severity Amoksiklav take 250 + 125 mg of active ingredient 3 times daily, at intervals of 8 hours or 500 + 125 mg twice a day, 12 hours apart.
In severe disease drug taking 500 + 125 mg three times a day or 875 + 125 mg twice a day, at intervals of 8 and 12 hours, respectively.
Depending on the complications of the disease, Amoxiclav take over 7-14 days.
Given that the effective Amoksiklav and sinus inflammation, it takes 500 + 125 mg of times per day and duration of therapy regulates physician. Note that in the sinus Amoxiclav not stop taking and after recovery for about 48 hours, even if the patient is no evidence of disease.
Amoksiklav in suspension - great for treatment if sick child, the dose is calculated on the weight of the patient. To prepare the suspension to the powder were added 86 ml of water in two stages and the mixture was well shaken to dissolve the powder. Before giving your child medication vial it must also be thoroughly shaken.
Infants up to 3 months Amoxiclav prescribed in the amount of 30 mg per 1 kg of weight. This volume was divided into 2 doses, the time interval between which is equal to 12 hours.
Children older than 3 months of age, the amount of the drug increased: by 25 mg given twice. If the average severity of disease, the drug can be assigned in the amount of 20 mg per 1 kg of weight, 3 times a day. In more complex cases, the dose may be 45mg per 1kg of weight, 2 times a day.
In Amoksiklava, as well as any other antibacterial drugs, there are side effects.
See also: Instructions for use to Amoksiklava
According to studies and reviews subjects side effects when using the drug "Amoxiclav" may affect the nervous system and the digestive, urinary and hematopoietic systems. Not less common allergic reaction.
Amoksiklava deleterious effect on the patient's body can manifest itself in the form:
- a heightened sense of anxiety;
- frustration of a chair;
- urticaria;
- flatulence;
- swelling;
- problems with the stomach work, intestines and digestive tract as a whole;
- Excessive stimulation;
- nausea and vomiting;
- convulsions;
- dermatitis and other skin reactions;
- dizziness;
- insomnia;
- headache or dizziness;
- anorexia;
- fungal infections and so forth.
Experience has shown that despite the presence of adverse reactions to the reception Amoksiklava, they are not pronounced and regress rather quickly.
Substitutes and cost
Today Amoxiclav has a lot of analogues. The most similar in terms of ingredients and the principle of action: Moksiklav, Augmentin, amoxicillin. But most often compared with Amoxiclav Flemoklav Soljutab, which included no clavulanate, which is much narrows the range of contraindications for use.
The average cost of Amoksiklava in the form of tablets varies within 240-600 rubles. Suspension for children can cost about 300 rubles.
Reviews of doctors and patients
In general, the opinion on "Amoxiclav" positive preparation. Many experts point out that this drug has a positive effect as a treatment for inflammatory diseases of the respiratory tract, and the urogenital area.
It is impossible not to note the fact that Amoxiclav equally effective in treating both children and adults. If the drug is assigned to the correct dosage and admission of multiplicity, and the patient adheres to all recommendations, recovery occurs as quickly as possible.
Many parents say that their children safely take the drug as a suspension, as it has a nice aroma and taste.
Notice of termination amoxiclav therapy should take drugs that restore the intestinal microflora. This is not news, because receiving any antibiotic has a negative impact on the microflora, destroying also own beneficial bacteria. To restore the body, enough to undergo treatment such means: Lactobacterin, Linex, Hilak Forte and others.
verified Article
Anna Moschovis - family doctor.
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