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Pancreatin or Mezim: which is better, what is the difference, differences, comparison

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What kind of medicine

Many people know from mezim from advertising, so this tool is so popular. Pancreatin is an analogue of foreign drugs produced by domestic pharmacological enterprises. Unlike its foreign counterpart, he is less well known, but has an identical mezim therapeutic effect.

Both tools are enzymatic means. They include the active substance secreted by the pancreas. These components help to digest food:

  • protease cleaves proteins;
  • lipase converts fats and fatty acids;
  • Amylase splits carbohydrates into monosaccharides.

Without enzymes, the digestive process is impossible. An important role in normal digestion used is the level of enzymes. Their deficiency causes stagnation of food masses in the intestine, appears uncomfortable and characteristic disruption GIT symptoms. Fill level of active substances may preparations containing enzymes.

But before you start treatment with these agents must pass tests to determine the level of intestinal enzymes. According to the results of tests the doctor will prescribe some medication, since the content of the active substances of different drugs is different. That is the difference between mezim and pancreatin, as well as other analogs of drugs.

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comparison of composition

If we compare Pancreatin and Mezim, we can see that they contain the identical active ingredients, namely - pancreatin. If we consider the structure closely, you can see that different funds will be the content of the excipients.

Comparison appearance

Another difference mezim of pancreatin is in the medicine appearance. Tablets mezim oblong, flat, saturated pink color, placed at 20 pc. on the planchette. Pancreatin release tablets, capsules or dragees pink and brown.

When prescribed medications

Enzymatic drugs well help with digestive tract dysfunction, associated with a lack of production of pancreatic enzymes.

Mezim prescribed for:

  • enzyme deficiency;
  • receiving a large amount of fatty foods;
  • chronic pancreatitis flow forms;
  • radiation therapy after surgery in the gastrointestinal tract;
  • digestive disorders of infectious origin;
  • IBS (irritable bowel syndrome);
  • in preparation for X-ray or ultrasound of the abdomen;
  • congestive processes in the gut;
  • swelling.

Indications for use of steel pancreatin:

  • hepatitis or chronic cholecystitis;
  • chronic form of pancreatitis;
  • overeating;
  • inflammation in the gastrointestinal tract organs;
  • the diarrhea of ​​bacterial etiology;
  • Preparation for ultrasound whether X-rays of the digestive tract.

Compare indications of drugs

Indications for use of the two drugs is not too different. Mezim differs from pancreatin action in these diseases. Since pancreatin is less active substances, it being prescribed with milder forms of enzyme deficiency diseases, gastrointestinal mild or moderate severity. Mezim has a prolonged therapeutic effect, so its use may be limited to receiving one day.

Features of application of preparations

Mezim belong to the new generation, providing a long therapeutic effect and with minimal adverse reactions. It can be given to children from three years.

Pancreatin referred to as the "old" proven remedy. Unlike mezim it has a number of side effects but has the advantage - low price. Agent is used in pediatrics, but it can give children from the age of six. Previously, drug use is not recommended.

Long-term use of enzymatic drugs can cause:

  • allergies;
  • epigastric pain;
  • frustration of a chair;
  • dyspepsia.

In children, higher doses of drugs cause constipation.

joint reception

Can not be taken simultaneously with Mezim pancreatin. If during treatment, the patient is dissatisfied with the therapeutic effect of the medication, it is impossible to increase the dosage on their own or to use both agents together. Taking Pancreatin with mezim, the patient increases the risk of "pobochki". Additionally, artificially adjustment enzyme deficiency with drugs at high doses leads to independently failure organism producing the desired active substances for the process digestion.

Contraindications to the use of drugs

Pancreatin Mezim and have the contraindications to the use of:

  • exacerbation of chronic gastrointestinal pathologies;
  • acute pancreatitis;
  • bowel obstruction;
  • renal coma;
  • drug intolerance components.

Supplementation during pregnancy

Unknown laboratory studies confirming the safety of drugs of this pharmacologic group of pregnant women and young mothers during the breast feeding. If you want such treatment, you can not use it without first consulting your doctor.

Before meals or after

Mezim take tablets or pancreatin before eating, drinking plenty of water. In this case, doctors recommend drink therapeutic enzymes alkaline water type Essentuki. The tablets can also be taken with food, but you can not chew the medication. During the reaction means with the saliva or the stomach contents, partially or completely neutralized drug therapeutic action.

analogs

festal

In the presence of allergy to components of the medication, the doctor prescribes, instead of taking Pancreatin Festal. It is more active drug, because unlike Pancreatin contains not one but three operating element. In addition it contains gemiellyuloza pancreatin and bile, so Festal helps to cope not only with fatty foods, but also coarse vegetable fiber. On medical action it is also superior to Pancreatin. Festal not only normalizes the gastrointestinal enzymatic level, but also improves intestinal motility and gallbladder.

Doctors recommend taking Festal for symptomatic treatment when necessary "shock" dose of enzymes. In the case of chronic diseases of the digestive tract flow Pancreatin used to perform replacement therapy. This treatment is indicated in patients with a slight imbalance of enzymes.

Creon

In moderate to severe pancreatic dysfunctions well-proven Creon. This analog Mezim preparation containing a greater concentration of the active elements.

The medicine is available in capsules and this differs from previous preparations. This form of the drug promotes uniform distribution of the active substances means around gastric tract. The capsule protects pancreatin pellets inside, protects them from premature reaction with hydrochloric acid. The process of release of the active substance starts at 12 and duodenum and moves further along the intestine. Another positive thing - the medicine evenly mixed with food and equally valid throughout the gastrointestinal tract.

Feedback from consumers, the well helps normalize digestion with severe violations of the liver, gallbladder and pancreas. The medicine is available in three dosages: 10 thousand. 25 tys.i 40 thousand. u For the purchase of the first two doses of a prescription is not required. Buy a third dose of the drug can be in a pharmacy only with a prescription.

Finally, a small

Mezim, Pancreatin and their analogues belong to the same pharmacological group. But systematically on their own to take medication is not necessary, since the means are different concentration of active substances, and frequent high doses of enzymes disrupt normal operation pancreas. Therefore, in case of violation of the digestive process, you should see a doctor, get tested and find out the cause of the problem.

sources:

Vidal: https://www.vidal.ru/drugs/pancreatin__25404
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 43524e11-4cf0-40a9-8931-ed1ef8c746b3 & t =

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