characteristics of drugs
Pancreatin is manufactured as a tablet form (125 mg, 100 mg, 90 mg or 25 units, 30 units). Tool helps digestion by adding enzymes. In medicine there are amylase, lipase, protease. Amylase is needed to break down the carbohydrate molecules. The protease is necessary for the digestion of protein molecules. Lipase helps to digest fats. All elements overcooked while taking pancreatin begin to be absorbed faster, which improves the patient's condition, prevents the occurrence of diarrheal syndrome, as well as swelling of the colon.
Indications for use of the drug:
- pancreatic dysfunction (with cystic fibrosis, inflammation of the prostate);
- the state after the removal of the colon;
- inflammatory and degenerative diseases of the digestive tract, which manifest diarrhea syndrome, increasing the amount of gas in the cavity ulcer, digestion insufficient bolus;
- poor diet, hypoplasia of the jaw, immobilization for several months or more;
- the use of drugs the day before medical procedures (X-ray and ultrasound examination of the digestive tract).
When using pancreatin may cause harmful effects. Patients may cause constipation, loose stools, nausea, gastralgia. Patients can increase the amount of uric acid in the urine. Children at high doses, have severe constipation. Children often complain about irritation of the anus during therapy pancreatin.
Pancreatin is not used in acute pancreatitis, insufficient liver function in patients with hepatitis, as well as jaundice syndrome. Do not use the drug in the presence of stones in the biliary tract, bowel obstruction. Some forms of pancreatin have higher dosage. They do not use in children under 3 years of age. Do not prescribe medication if you are allergic to its components. The price of the drug in online pharmacies is 38-75 rubles.
Digestive pathology associated with dysfunction of the pancreas in pediatric practice
Can I Pancreatin children? Pancreatin is used in pathology digestion with pancreatic insufficiency. Pancreatic insufficiency is often develops in the wrong diet, cystic fibrosis.
Attenuation function of the pancreas in children may occur in congenital deficiency of enzymes. State also causes damage to the 12 duodenal ulcer and other diseases. Violation of the pancreas can be observed in pancreatitis. Inflammation of the pancreas in children - is a rare pathology. The disease is more common in adults.
Often appears pancreatic insufficiency in children with malnutrition.
Abundant use of food a child provokes a lack of enzymes in relation to the food bolus. Also shortage of work of the pancreas develops in the presence in the diet of a large amount of protein and high fat foods. In this case, the pancreas is unable to cope with their work, because the breakdown of proteins and fats take longer enzymatic compounds.
Pancreatic insufficiency manifests itself in violation of the chair, abdominal pain. Children may become more frequent stools. stool frequency may be up to three times or more. stool color can be more bright and bold. In children, diarrhea, constipation is replaced.
Cystic fibrosis
Giving your child a must Pancreatin in cystic fibrosis. The disease can be diagnosed at birth. This disease is hereditary. In cystic fibrosis disrupted ductless glands. More on pathology damaged pancreas, respiratory system. In patients increases the amount of electrolytes in sweat. Most often the disease occurs in people of white race.
Patients with cystic fibrosis are often damaged respiratory system in the form of bronchitis and other manifestations of possible obstruction of the airway. respiratory pathology often recur. Patients also compromised digestive function. Absorption of nutrients in the intestine is difficult. Digestion and absorption of fat and protein molecules is broken.
Stool of patients have a gray tint. Chair characterized unpleasant odor. Frequent urge to defecate, bulky stools. Against the background of these symptoms is likely rectal prolapse, especially in children 2-3 years of age.
In children, there is poor absorption of vitamins. In severe steatorrhea (gray chair) says a severe deficiency of vitamin E, D, A. These vitamins are poorly absorbed because they are fat-soluble.
The secret in the intestinal glands is very thick and sticky. Water absorption in the intestinal tube is higher than in a healthy patient. These reasons lead to the emergence of constipation. Stool can be very hard, because of what is developing intestinal obstruction.
Since the secretion of sweat glands strengthened electrolytes through sweat out much more than healthy children. When excessive sweating of the child devour much pressure drop or shock occur.
Pancreatin for newborns shown in cystic fibrosis since birth. After 48 hours of life in children meconium slightly delayed. Meconium become sticky mass that is diagnostic of cystic fibrosis in children during the first days of life. If the pancreatic insufficiency is heavy, then the child has bowel obstruction. When the correction of the pancreas dysfunction in the baby chair is adjusted. Therapy helps prevent the development of bowel obstruction.
Terms of Use medication the child
Pancreatic insufficiency treated with drugs of pancreatin. Pancreatin take the child can be in the form of powder, tablets, capsules. Pancreatin itself can be used as a powder for babies who can not take pills. pancreatin tablets used for children over 3 years of age, if the dose of lipase in tablet form large (3-4 thousand units).
The dosages of medications for babies up to 12 months
For babies up to 12 months, there is a special scheme of calculations. Pancreatin is calculated by lipase. This is very important because during the digestion of fat digestion requires more energy and enzymes. Most often disturbed lipolysis.
Baby taking Pancreatin can be from birth, if there is pancreatic insufficiency. For kids the dosage of the drug selects the Neonatologist by body weight. If the time to begin therapy symptoms of pancreatic insufficiency can be eliminated. The same circuit is shared in infants.
Pancreatin dosage for children up to 12 months at a moderate thyroid dysfunction:
Mass kid (kg) |
Dosages (for lipase) |
4 |
1200 IU per 1 meal (mixture of mother's milk, purees) (6000 IU per day) |
7 |
2500 IU per 1 meal (12,500 IU per day) |
10 |
3500 IU per 1 meal (17,500 IU per day) |
Example: If a newborn baby is eating 5 times, then give the medicine you need 1200 IU (of lipase). To learn daily dosage of pancreatin have to be multiplied by 1200 5. It turns out 6,000 units. If a child eats 6 times the dose per day is 7,200 IU.
If necessary, the dose can be reduced or increased. Maximum dosage for a child under 12 months of age is 50 000 units for the cut. Dosages are selected depending on the severity of clinical symptoms. If the patient does not tolerate pancreatin, the dose of medication is reduced or canceled drug.
Kids give Pancreatin in powder form. Pound tablet form, diluted with water or milk. It is better to give the medicine from the beaker or measuring spoon. Pancreatin necessarily provide meals. Means mixed with the bolus and helps to break down fats, proteins and carbohydrates. It is not necessary to give medicine after meals.
Children Pancreatin in Pharmacy is, but it is also produced in tablet form. Tablet for kids need to grind or replace analogue in the form of capsules. The most convenient is the analogue for infants Pangrol. It has within its capsule tabletochki small capsules, each of which contains a dose of 500 IU of lipase. The total enzymatic activity of the drug is 10,000 and 20,000 units. This greatly facilitates the use of drugs.
Coursework pancreatin therapy may continue for 2-4 weeks. If a child has cystic fibrosis, he is a replacement therapy enzymatic preparations throughout life. In cystic fibrosis in children, the dosage should not exceed 10,000 IU per 1 kg per day. A dose higher than this may disturb the digestive function, lead to constipation and obstruction.
The dosage for children over 12 months
For patients of 12 months the dose is also considered by weight. The dosage is calculated according to the amount of lipase. Scientists have deduced the optimal dose (average) lipase for childhood. It is 500 IU.
Pancreatin dosage for patients 12 months of age (by lipase):
Age (in years) |
Dosage (IU per 1 kg per day) |
1-5 years of age |
1500-1000 |
5-17 years of age |
1000-500 |
Example: If a baby weighing 12 kg at 2 years, the 1500 multiplied by 12. It turns out 18,000 units of lipase. This dosage gives a child a day. This dose is distributed evenly on each feeding.
In calculating the dosage of a child 17 years old (girl) looking at her weight. Assume teenage girl weighing 50 kg. To calculate the necessary daily dose of 500 IU of lipase multiplied by 50 kg. It turns out 25,000 units per day. This amount is divided into 3-4 meals.
Pancreatin dosage maximum for children over the age of 18 is 100,000 units per day, and for children up to the age of 18 - 50,000 units. If taking high doses, may cause constipation and digestive disorders.
Pancreatin children, according to the instructions received in the following dosages:
- 3-5 years of age -1 tablet form (for 1 dose);
- 6-7 years of age -1-2 tablet form;
- 8-9 years of age - 2 tablet form;
- 10-14 years of age - 2-4 tablet form.
Children under 3 years of age should take the drug in powder form, tablet form because they can not drink. Pancreatin for children from 3 years prescribed in tablet form. Tablets are coated, which increases the effectiveness of treatment. The casing protects the enzymes from damage digestive juice, as well as from deactivation.
conclusion
Pancreatin is considered to be a good drug for the treatment of pancreatic insufficiency, caused by digestive diseases and cystic fibrosis. The medicine is suitable as a replacement therapy, even in newborn babies. With proper selection of the dosage of pancreatin likelihood of adverse events is minimal. Calculate the dose of medication should be a doctor. Self-apply the medicine in children is impossible. Overdose can lead to constipation and bowel obstruction.
sources:
Vidal: https://www.vidal.ru/drugs/pancreatin__25404
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 43524e11-4cf0-40a9-8931-ed1ef8c746b3 & t =
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