Mydocalm - a muscle relaxant analgesic central action. Mydocalm take before meals or after depends on the recommendations of the attending physician, the manufacturer of the drug gives general recommendations for application.
Dependence on food assimilation
The manufacturer recommends taking Mydocalm before eating. This is due to the pharmacokinetics of the drug. The active substance - tolperisone - absorbed by the small intestine. The maximum drug concentration achieved one hour after the application of blood. During this time, the pain associated with excessive muscle tension and spasms, must cease.
Fatty food increases the bioavailability of the drug after ingestion of almost one hundred percent. Increases and the maximum plasma concentration is approximately 45% compared with fasting. When applying Mydocalm tablets on an empty stomach is marked delayed effect of the drug - an anesthetic and muscle relaxant effect is thirty minutes longer.
Mode of application
Manufacturers of the drug is recommended to drink Mydocalm before meals with the required amount of water. A small meal reduces the bioavailability of the drug, because nutrition is recommended during treatment.
Mydocalm dosage, as well as how to take: before eating or after, will recommend to the physician. The dosage is adjusted individually, depending on tolerability and individual needs.
The daily effective dosage of from 150 to 450 mg, divided into three doses at various time intervals. Tablets should not be chewed. Maybe an appointment one or two times a day - rate and frequency of application are determined individually.
If the kidney function
Available data on efficacy in this patient group is not enough. With moderate renal disease increases the likelihood of side effects. It is recommended to take a limited dose, and in severe kidney disease refuse treatment Mydocalm.
Careful control of the state of patients with kidney lesions during therapy Mydocalm. The dosage should be individualized.
If abnormal liver function
At moderate severity of hepatic lesions Mydocalm can be used in the treatment, but requires careful selection of dosage. The physician can individually specify Mydocalm drink before meals or after, for individual titration required effective dosage.
In severe liver damage is not recommended treatment Mydocalm.
Pregnancy
Mydocalm can be used in the treatment of diseases in pregnant women, but you need to follow these guidelines:
- Mydocalm not use in the first trimester of pregnancy;
- carefully titrate the dose to the minimum effective dose;
- watch the state of the mother and fetus;
- upon detection of any adverse reactions, stop the drug or to choose a safe analogue.
In the second and third trimester Mydocalm prescribed only under the close supervision of the attending physician, considering the risks and benefits to the fetus and mother.
children
Mydocalm treatment is not practiced in pediatrics because prescribe it to children and teenagers under eighteen years of age is contraindicated.
lactation
There are no reliable data on whether the drug passes into breast milk. Use during breastfeeding can harm the fetus, because, if necessary, treatment should be feeding on.
conclusion
Mydocalm helps with muscle spasm, the accompanying diseases of the musculoskeletal system. It is recommended to take before meals for better absorption, but the doctor can be assigned to a different circuit applications.
sources:
Vidal: https://www.vidal.ru/drugs/mydocalm__31619
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 7d7d4f70-ea02-447f-b964-2ef987a6e9ac & t =
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