Mydocalm - is a muscle relaxant that is used in diseases of the nervous system, accompanied by spastic muscle lesions, as well as in combination with non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of diseases spine. Mydocalm of the stomach is not fully understood, but according to an official statement the drug can cause indigestion, stomach pain, nausea, vomiting. These manifestations during the study drug is very rare.
Pharmacological properties, release forms, indications
Mydocalm is a central muscle relaxant, relaxing striated muscles. This effect is due to lower drug transport potassium ions across the neuronal membrane, inhibition of transmission of nerve a pulse motor in the synapses of the nerve cells, prevents the adrenoceptors, receiving and transmitting information to brain stem.
The drug is produced in two forms: tablets, injections. Active drug component is tolperisone hydrochloride.
The concentration of the substance:
- tablets (50.150 mg);
- vials (1 ml - 100 mg tolperisone hydrochloride, 2.5 mg Lidocaine hydrochloride).
Indications and limitations to the appointment of the drug
testimony |
restrictions |
|
· Spastic muscle damage of central origin; · Diseases of joints and spine; · Cerebral palsy of spastic type; · Obliterating vascular disease. |
· Pregnant women, lactating women; · Children up to 3 years (tablet) to 18 years (injections); · Intolerance to the drug components; · Myasthenia gravis. |
The most common undesirable effects are:
- muscle weakness;
- hypotension;
- abdominal discomfort;
- allergy;
- dyspepsia.
The impact of the drug on the digestive system
In the study revealed rare Mydocalm reaction from the digestive tract. In some patients (1: 10,000) following complaints were made: a sore stomach from Mydocalm also experienced constipation, bloating.
Often after Mydocalm stomach ache while taking non-steroidal anti-inflammatory drugs. They are irritating to the stomach lining. NSAIDs often provoke gastritis, and ulcerative lesions of the digestive tract.
To reduce the intensity of the irritant effect of the drug on the stomach Mydocalm patients, it is necessary to cancel the non-steroidal anti-inflammatory drugs. If dyspepsia symptoms appeared overdose tablet form, it is necessary to stop the drug, gastric lavage, activated charcoal to drink (smectite, Entrosgel). When administered parenterally the negative effects of the drug helps to ease the infusion therapy.
Drug analogues are:
- Tolizor;
- tolperisone;
- Tolperisone hydrochloride.
conclusion
Midoklm drug has the ability to irritate the stomach. This undesirable effect is not often detected. Co-administration of NSAIDs increases the probability of occurrence of dyspepsia. To reduce the risk of undesirable manifestations and complications prior to use of the drug is necessary to consult a doctor to clarify the rules of the drug.
sources:
Vidal: https://www.vidal.ru/drugs/mydocalm__31619
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 7d7d4f70-ea02-447f-b964-2ef987a6e9ac & t =
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