Antibiotics and alcohol are incompatible with the joint use they provoke side effects that are hazardous to health. Preparing for the holidays, people, after treatment sumamed, asked: "How many Sumamed derived from the body?" For answer to study what happens after the administration of the drug into and through means which time is completely removed from body.
What happens after receiving medicament
Application Details sumamed instruction indicates that the current active drug substance is azithromycin.
Upon receiving the drug means there is the following:
- Once in the stomach, azithromycin begins to actively absorbed through the mucosa, getting into the bloodstream;
- Wind- bloodstream active elements distributed start preparation, settling at the site of infection;
- One hour after the dose in the lesion marked Sumamed concentration required to initiate the destruction of the bacterial flora;
- After 5-7 hours at the site of infection the amount of drug is maximized.
Sumamed acts quickly and the effect of the application is felt for 2-3 hours. To maintain the necessary concentration to be taken once a day, the next therapeutic dose.
Sumamed excretion from the body is through the liver bile. Metabolites accumulate in the hepatocytes (liver cells) and through the bile ducts come first in the gall bladder, and then into the intestine and excreted in the feces.
When to expect the complete elimination
Consider how many Sumamed will indicate via the hepatic ducts in several stages:
- "Working" in the lesion medications fall into active metabolites (occurs over 36-72 hours);
- half particles washed out bloodstream of pathological nidus, are deposited on the liver cells;
- Of semi-active hepatocytes Sumamed enters the bile duct, then through the gut eliminated from the body.
Excreted excretion Sumamed period is 5-6 days thereafter terminate the therapeutic effect of the medicament. The fact that the drug is removed from the tissue slowly increases the effectiveness of drugs and allows long-term therapy, Sumamed taken once a week.
If the cure is continued for a long time, when the patient has to take the drug on a weekly basis, the period of full withdrawal is extended.
It should be remembered that the active metabolites in plasma is stored up to 2-3 weeks, and despite the low curative activity, may trigger unwanted side effects, so you need to wait until they are completely removed from the blood and tissues.
Knowing the time of excretion of the drug, it is possible to avoid the negative consequences associated with the consumption of alcohol or taking other medications that are incompatible with Sumamed. In order to prevent undesirable effects, doctors recommend to wait 3 weeks for the complete elimination of metabolites of the drug on the basis of azithromycin.
sources:
Vidal: https://www.vidal.ru/drugs/sumamed__786
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 5b4a2b6f-bdfe-4437-a8d7-6db45ea45782 & t =
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