Modern medicines for common diseases herpes have an effective impact and help get rid of the virus. However, many people are pressing question - which is better: Zovirax or Acyclovir? Both have similar exposure to the drug, but the choice of drugs is required to take into account many important factors. In spite of the same composition, the drugs still have some differences.
Structure
Currently provided by the manufacturer are several effective forms of both drugs issue - ointments, creams, tablets. To completely eliminate the disease, it needs to use drugs in the complex. Tablet formulation of the medicament comprises 200 mg of active compound, but cream is usually produced in a tube 50 g.
ointments
Medicinal ointment have different concentrations of active ingredient. There ointment containing 5% acyclovir ophthalmic cream and has a concentration of 3%.
Both medication belong to a group of antiviral agents. In their composition contains an active drug acyclovir. This nucleoside was synthesized in the last century, and has some similarities with the natural guanosine. Opening nucleoside was honored with the Nobel Prize. Its effect on pathogens subjected to numerous studies, and the results recorded.
Besides the basic substance, Zovirax cream composition comprising:
- dimethicone;
- propylene glycol;
- glycerol;
- cetostearyl alcohol;
- liquid paraffin.
These adjuvants provide a soft smooth consistency drug. They help the main nucleoside block reproduction of the virus, as well as create a soft homogeneous structure of the drug.
Comparing the two compounds, it can be seen that the acyclovir cream contains:
- polyethylene oxide;
- lipokomp;
- nipazol;
- nipagine;
- emulsifiers.
That composition is different from Acyclovir Zovirax. Acyclovir ointment and Zovirax have the same concentration of active substance. However, very different auxiliary components in them. However, the action of the primary drug substance like no significant effect. Ointment 5% of the Russian producer Ozone Ltd and the Belarusian producer Belmedpreparaty contains in its composition of only a polyethylene glycol group of excipients. Acyclovir cream from the company NIZHFARM more complex composition comprises.
Acyclovir ointment 5% enriched lipokompom. This component is an extract of natural chicken fat. Zovirax ointment produced as only a 3% concentration. Acyclovir cream made with 3% and 5% active ingredient content. Both drugs are designed to treat keratitis. It is necessary to understand correctly in testimony to the use of both drugs.
tablet form
Acyclovir Tablet comprising a main component of the same name acyclovir, as well as certain auxiliary substances:
- lactose;
- starch;
- milk sugar;
- stearic calcium.
Virtually identical composition include Zovirax tablets. Manufacturer included in their composition adjuvants - such as lactose, magnesium stearate, povidone, starch, cellulose.
Both drugs dissolve rapidly in the gastrointestinal tact, and their components enter the blood stream. Ingredients tablets have a powerful anti-virus attack and destroy pathogens.
properties
What is the difference between acyclovir and Zovirax? Judging by the properties of the two drugs, their action in the lesion same. herpes virus is a DNA-containing pathogenic microorganisms. Acyclovir destroys the DNA of the virus and stop its further life activity. Both antiviral drugs are synthetic analogs of thymidine nucleoside.
Affected herpes infection cells contain thymidine kinase. Thymidine is converted into the source of infection in the active substance Acyclovir. With the application of medicament substance accumulates in infected cells and stimulates their destruction.
How does Acyclovir
The components of the drug embedded in the DNA of the virus and inhibit its reproduction. As a result:
- inflammatory focus is gradually reduced;
- Herpes on the lip becomes smaller and disappears;
- increases local immunity;
- there is no re-occurrence of herpes.
Acyclovir agent has no toxicity and high effect in human body safely. In addition to herpes, ointment and tablets used in the treatment of genital lesions, herpes zoster, varicella.
Medicine may cause some adverse reactions - diarrhea, constipation, headaches, disturbances in the nervous system. Take tablet Acyclovir according to the instructions with water. The ointment is applied to the skin of the lips. Course the doctor prescribes individually.
How does Zovirax
Zovirax components inhibit the enzyme activity of the DNA polymerase. Such effects are not giving herpes to develop further. The virus can no longer exist in the cell and dies. Comparison Zovirax ointment and Acyclovir shows that both tools are absolutely identical. A feature of the drug Zovirax is perhaps that the higher cost.
The drug Zovirax shown for use against herpes, in the treatment of various skin infections as well as for their prophylaxis.
The drug can cause in an individual case, side effects - headache, disturbances in bowel habits, disorders of the central nervous system.
It's important to know! Zovirax is the drug of the original, and Acyclovir - its efficient, widespread generic, analogue of Zovirax.
Zovirax Ointment 3% is used to treat the eye. Means applied neat movements in the lower eyelid. Use a medicine can be not more than 5 times a day. Also in the manual it says that treatment should always be carried out before the infection is completely treated.
Take Zovirax herpes virus can be when people with normal immune systems, as well as patients with immunodeficiency. Zovirax tablet should be swallowed whole. Zovirax Ointment is applied topically.
differences
Furthermore composition auxiliary components, a difference of the two drugs is a manufacturer. Medicine Zovirax is made in England, and Acyclovir cream is produced in Russia. When asked what the best of medicines, there is no single answer. Significantly different medicines in the price - medication Zovirax worth in domestic pharmacies are much more expensive. Its price ranges 196 rubles for a tube of ointment to 1600 rubles for ampoules for injections.
Acyclovir has more contraindications. The medicine should not be taken expectant and nursing mothers, infants and young children. Zovirax, on the contrary, may prescribe a pregnant or nursing woman. Zovirax also means shall be used in the treatment of babies.
Instead Acyclovir Zovirax and in the treatment of skin diseases can be used analogues:
- Geviran;
- Valtrex;
- gerpevir;
- Viroleks.
Based on this article, it can be concluded that it is better and safer - the original drug Zovirax from the English manufacturer. The drug produced by the pharmaceutical company GlaxoSmithKline (country - Great Britain). It is less toxic and virtually no side effects. Zovirax acts on the body more delicately and gently, without causing drastic adverse events. Receiving generic Acyclovir has a more aggressive effect inside the human body.
Based on the initial price of both drugs, of course, to be preferred to the domestic composition of Acyclovir. This is especially useful when there is no large sums of money for the treatment of cold sores. It all depends on the financial possibilities of the patient.
Take two of the drug with a dosage form is strictly prohibited. You must be a threat of overdose. Both tools, and Acyclovir Zovirax, in their compositions have exactly the same active substance. With his overdose dangerous consequences may be irreversible.
However, the complex can be used tablets and ointment of one manufacturer. That is, the patient can be used inside tablets and ointment to smear on your lip herpes. A double blow to infection necessarily eliminate illness and allow quicker to embark on the road to recovery. In pediatric patients, caution should prescribe acyclovir ointment. Its application requires medical supervision. It is advisable to use a secure children's treatment Zovirax.
sources:
Vidal: https://www.vidal.ru/drugs/aciclovir__4107
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 1c2f1271-35fa-497d-b17d-07060cf7e6d7 & t =
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