In acute and chronic respiratory diseases, which are accompanied by inflammation and excessive accumulation of mucus in the airways, doctors often recommend Erespal. Initiation of treatment, patients want to learn how to act quickly begins Erespal.
Composition, form of the drug release
Erespal refers to drugs that affect the respiratory system. He is appointed for obstructive diseases. The main active ingredient is fenspirid.
Erespal available in tablet form and syrup. The tablets contained 80 mg of fenspiride hydrochloride, and syrup 200 mg / 100 ml.
pharmacological features
Erespal antibronhokonstriktornoe and anti-inflammatory action. When receiving the drug:
- decreases bronchial smooth muscle spasm;
- It decreases the production of a number of biologically active substances that cause inflammation and bronchoconstriction: free radicals tsikotinov, arachidonic acid derivatives;
- observed H1-antigistaminnoe effect;
- α-adrenergic receptors are blocked, which increases when stimulated secretion of bronchial glands.
Due to this influence extends inflammation, decreases mucus production, reduced oropharyngeal mucosa edema, cough, and passes nasal congestion.
Tablet begins to be absorbed from the intestine after dissolving the coating film. Fenspiride maximum concentration observed after 6 hours after administration of tablets.
Erespal syrup starts to act faster. The maximum concentration observed after 2.3 hours. But the period of achieving Cmax when applying the syrup can vary from 0.5 to 8 hours.
The period poluvyvoda Erespal does not depend on the shape of the drug release. It is 12 hours. Fenspirid body gets rid of through the kidneys.
length of treatment
Appoint Erespal adults and children must be a doctor. Depending on the condition of the patient, the severity of the symptoms of inflammation, cough intensity selected desired dosage and duration of treatment is established. It will depend on how quickly Erespal acts on the body of the individual.
In accordance with the instructions in uncomplicated cases, an adult is recommended to take 2 tablets before meals. If necessary, the dosage may be increased up to 3 tablets a day Erespal.
Children designate means, focusing on weight and age. A child under the age of 2 years Erespal impossible.
To the drug began to help the child's body in a day should do fenspirid 4 mg per 1 kg of weight. This corresponds to 2 ml Erespal syrup. Children aged 2-12 years who weigh more than 10 kg, it is recommended to give 30-60 ml Erespal per day, which corresponds to 60-120 mg fenspirona. After 12 years, the recommended dosage is increased up to 45-90 ml.
Erespal speed of action depends on the established diagnosis. In acute bronchitis, rhinopharyngitis, laryngotracheitis more than 90% of the patients at admission Erespal recover for 10 days. According to the research of the disease symptoms disappear between 7 and 10 day treatment. Fast action is due to a combination of anti-allergic, spazmaliticheskogo, anti-inflammatory influence.
Many doctors recommend that patients come again after 5 days of treatment. This is necessary to assess the effectiveness of the prescribed therapy. When using analogues produced by fenspirid, the rate of recovery is not changed.
sources:
Vidal: https://www.vidal.ru/drugs/phenybut
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = ea72a4ab-3d5e-4f67-9cbf-a597acb50ce1 & t =
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