Treatment of pathologies of the gastrointestinal tract (GI tract) during pregnancy is carried out medical drugs are not toxic to the embryo. Omeprazole is used during pregnancy, in exceptional cases, when use of the drug is greater than the potential harm. Why does it take caution when using omeprazole during pregnancy, any pathology in the development of the baby can cause this means, consider further.
pharmacological properties
Omeprazole is included in the group of drugs that are recommended for peptic ulcer. Its pharmacodynamics due to decreased activity of the enzyme components of H + / K + - ATP phase, called proton pump inhibition. Drug action is due to the omeprazole active substances to reach the stomach, and their interaction with the acidic medium. After oral administration ingredients funds accumulated in individual cells of the gastrointestinal tract, normalizing process of developing gastric juice, thereby achieving a normal level of acidity.
On a note! The therapeutic effects of the drug depends on the dosage and becomes noticeable in the second to fourth day of treatment.
Active ingredients are rapidly absorbed omeprazole, its bioavailability is about 40%. Processed medicament liver and excreted naturally by the kidneys. This is another reason that the omeprazole during pregnancy prescribed with caution. Since the load on the kidneys in pregnant women increases.
Omeprazole and pregnancy
Omeprazole belongs to a group of medicines category C - the results of clinical tests found its negative impact on the child's development in the womb.
Attention! Take Omeprazole pregnant in early pregnancy is not recommended. In addition to increasing the load on the mother's kidney, the drug can cause developmental disorders of the cardiovascular system of the baby.
If you take Omeprazole during early pregnancy is prohibited WHO, the Russian Ministry of Health is not so categorical. Therefore, you can be prescribed the drug, since the third trimester of pregnancy. However, for this purpose have to be life-saving when the risk to the baby's lower than the benefit to the mother.
Feeding is not a direct contraindication. However, during lactation is better to abstain from the use of funds. This is due to its ability to accumulate in the mammary glands and excreted in milk.
Scope
Medicament preparation is used in the treatment of a wide range of pathologies top of the gastrointestinal tract.
Omeprazole is indicated for:
- Stomach ulcer that is caused by infection with Helicobacter;
- Increased secretion;
- Gastropathy caused by the use of nonsteroidal antiinflammatory drugs;
- tumors;
- osteoporosis;
- Infections of the stomach;
- Heartburn.
Final to decide whether pregnant Omeprazole can only medical consultation, which includes a gynecologist, and a gastroenterologist.
Contraindications and side effects
Omez Instructions (omeprazole) lists a disease or condition, during which its reception is undesirable:
- The first trimester of pregnancy;
- Lactation;
- Impaired liver or kidney;
- The presence of histamine (allergic) displays on the components of the formulation.
In most cases, it means well tolerated, even during pregnancy. But the violation of dosages or longer duration of therapy (more than 3 months) can cause symptoms of adverse reactions:
- The drying of the mouth;
- Dyspeptic symptoms (flatulence, nausea, vomiting, impaired stool);
- Violations of the emotional state;
- Allergy;
- Dizziness and disorientation;
- Respiratory disorders;
- Chills;
- Changes in blood counts;
- Muscle pain;
- General weakness and fatigue.
Be careful! If you drink during pregnancy omeprazole, it can trigger the development of abnormalities in the baby, including incompatible with life.
special instructions
Take Omeprazole can be pregnant, if you follow the rules of application. Not liquid drug is not to have a negative effect on the mucous membrane, the capsule should be swallowed. Most often attributed to one-time use of the drug. Usually capsule is taken orally in the morning before eating. Wash down the tablet small amount of pure non-carbonated water.
The dosage of the drug during pregnancy should be selected by the attending physician taking into account the condition of the patient. The maximum daily intake should not exceed 20 milligrams. The duration of therapy during pregnancy is from fourteen to sixty days. Then you need a break for 1-2 months.
Omeprazole - a means by which to pregnancy should be abandoned. If his appointment is required, it is quite possible since the middle of the third trimester of pregnancy. During this period, the risk of fetal abnormalities is minimized.
sources:
Vidal: https://www.vidal.ru/drugs/omeprazol__3120
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 83097c54-4fcd-4122-b96d-1b90b38d8823 & t =
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