The network can sometimes be found quite strange request - "Loratadine - an antibiotic or not?". Despite the fact that the actual Loratadine and any of the antibacterial drugs - are drugs from completely different groups with different mechanisms of action, such issues are sometimes found.
Mechanism of action
Antibiotics - are substances which exhibit the ability to inhibit the growth and reproduction of microorganisms in small concentrations.
The mechanism of antimicrobial action from antibiotics may be as follows:
- Violation of protein synthesis of the bacterial cell;
- Interference with the synthesis of nucleic acids;
- Report synthesis of cell wall components of bacteria processes;
- Direct damage to the membranes or disruption of their normal operation;
- Interference with the synthesis processes of purines and pyrimidines;
- Inhibition of normal respiratory activity of bacterial enzymes.
Loratadine - it is not an antibiotic and has nothing to do with it. Loratadine and other similar drugs - a blocker of H1 histamine receptors. These means prevent the occurrence and reduce the severity of allergic reactions by preventing receptors blocking action of histamine on the vasculature, smooth muscles, and lowers the permeability capillaries.
Loratadine is not able to penetrate the blood-brain barrier, and thus has no marked effect on the central nervous system. No effect on the duration of electrical systole during ventricular electrocardiographic examination.
Indications for the use of antibiotics and Loratadine
Accordingly, different, and indications for the purpose of loratadine and an antibiotic. Antibiotics are indicated for a wide variety of diseases caused by pathogenic and opportunistic pathogenic microorganisms, and absolutely useless for allergic reactions and psevdoalergii.
Use of histamine receptor blocker is shown in the following cases:
- In allergic rhinitis, conjunctivitis, hay fever;
- With urticaria, eczema, contact dermatitis;
- In case of allergic reactions to pollen, insect bites or contact with other allergens to relieve symptoms;
- It is effective in the case pseudoallergy arising after the use of histamine releasing preparations and food products;
- It is sometimes used in bronchial asthma, but solely as an auxiliary agent (drug has weak bronchodilatory effect).
Loratadine is available in tablet form and in syrup form, and therefore suitable for children. In this case, a variety of unique and low prices make blockers histamine receptors available to most patients.
Sharing with antibiotics
But antibiotics with loratadine requires cautionAs some of them, increase the concentration of histamine receptor blocker in blood plasma. In turn, reduces the concentration of loratadine some macrolides (such as, e.g., erythromycin) and antifungal antibiotics such as Fluconazole and ketoconazole that require dose adjustment or the use of other combination of drugs.
The drug does not potentiate the effects of alcohol on the central nervous system. Teturamopodobnogo effect in the treatment of loratadine, as opposed to some antibiotics, is not observed. However, during the administration of the drug to drink alcohol still not worth it.
sources:
Vidal: https://www.vidal.ru/drugs/loratadine__3595
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 86d9d5c6-cd64-49e4-8081-c35aa2f78371 & t =
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