Symptomatology and etiology of hangover
Hangover is a complex of symptoms that appear as a result of excessive drinking. It develops after some time as a result of average and extreme intoxication.
Hangover is determined by the following features:
- headache;
- thirst;
- weakness;
- nervousness;
- nausea;
- vomiting;
- redness of the eye;
- insomnia;
- lack of appetite;
- shumoboyazn;
- photophobia;
- diarrhea;
- body aches;
- depression;
- apathy.
Often during a hangover can be observed "adrenaline longing" - a sense of guilt and shame, a sense of perfect improper act. This occurs under the influence accumulated in cells of the hypothalamus neurotransmitter adrenaline, which is produced in significant amounts at abusing alcohol.
The causes of a hangover
Identify several causes of a hangover. The first is based on the ability of ethanol to increase urine production, which contributes to dehydration. Against this background, headaches and constant thirst.
The second cause of this condition are substances that are formed after breakup of ethyl alcohol. Alcohol dehydrogenase enzyme oxidizes ethanol to acetaldehyde is further transformed into ethanoic acid. At a high content of alcohol in blood enzymes can not neutralize it properly, acetaldehyde is oxidized to ethane acid accumulates in the body. This material is almost several tens of times more toxic than ethanol. It is with the aim of removing acetaldehyde from the body, experts recommend hangover drink activated charcoal.
Also during the active processing of ethanol disturbed carbohydrate metabolism in the liver of - causing the cerebral glucose concentration decreases cells - the primary energy source. This phenomenon explains the feeling of weakness, fatigue, irritability, impaired concentration.
Furthermore, worsen the next day after alcohol abuse, substance can accompanying alcoholic fermentation (fusel oils), nicotine and magnesium deficiency in an organism.
General instruction for the application of activated carbon
Activated carbon - black substance, which has a porous structure. Means obtained by carbonizing (calcining in a special furnace) natural carbonaceous materials: coal, wood, coconut hard shell and so on.
Indications and contraindications
Applied activated carbon hangover, in the treatment of various intoxications, viral and bacterial infections of the gastrointestinal tract, increased gas, certain types of allergy.
Indications
According to the instructions, the tool is assigned to the following diseases:
- intoxication exogenous and endogenous nature;
- dysentery and salmonellosis in the treatment;
- medicine poisoning, heavy metal compounds, alkaloids and other toxic agents;
- dyspeptic disorders and increased flatulence;
- allergy to medicines or food;
- increased bilirubin level in various types of hepatitis;
- increase in nitrogenous products of protein processing in patients with renal insufficiency;
- preparations for ultrasound and X-ray methods of investigation in order to remove the gas bubbles.
Also, activated carbon is used for the prevention of poisoning in hazardous industries.
Contraindications
In spite of the relative safety of activated carbon, it has some limitations to receive:
- idiosyncrasy;
- ulcerative gastrointestinal disease;
- decrease intestinal motility;
- gastrointestinal bleeding;
- Children up to age 3 years.
Activated carbon is not administered with other detoxication agents, the therapeutic effect which occurs after absorption.
Dosage and Administration
The drug is taken orally for 2 hours before taking other medications. It is better to drink activated charcoal in the morning, with a hangover should take it on an empty stomach.
The dosage depends on the individual and the disease. Typically, activated carbon is appointed by 250-750 mg 3-4 times a day.
Side effect
The drug rarely causes adverse effects. When used regularly, may be in breach of the chair and absorption in the gastrointestinal tract.
The mechanism of action of the activated carbon with a hangover
Activated charcoal helps with hangovers due enterosorbiruyuschee, antidiarrheal action and the ability to neutralize toxic substances. Due to the porous structure, it collects on the surface of ethanol oxidation toxic products from the gastrointestinal tract before absorption and removes them naturally.
Addition of acetaldehyde, the activated carbon adsorbs and outputs gases, drugs, heavy compounds metal poisons natural origin, derivatives of hydrocyanic acid, phenol and other toxic agents. Moreover, the drug clears from the body of excess urea, bilirubin, and cholesterol.
The use of activated carbon with a hangover
Activated carbon is able to quickly assist with hangover. Appreciable therapeutic effect of the drug develops within the first two hours after application.
Activated charcoal method at hangover
The dosage of activated carbon with a hangover is determined komplektsiej patient and the severity of his condition. Typically, the drug is taken hangover cure rate of 250 mg per 10 kg body weight.
The drug is administered orally, washing down the necessary quantity of water. For a more pronounced efficiency can be crushed tablet form to a powder and take it as a slurry with water, or to purchase the drug in capsules.
Properties of activated carbon receiving hangover
Coal should drink on an empty stomachAs well as the contents of the stomach can significantly increase the time before the start of its operation. It is not necessary to use the tool with other sorbents, as they have a negative impact on the effectiveness of each other.
In severe hangover or acute alcoholic poisoning should make water gastric lavage with activated carbon powder. Further inward to take 30 g of the drug. This will create an excess of activated carbon in the gastrointestinal tract and release the remainder of the stomach from food and toxins that had not managed to get into the blood.
After washing, white carbon can be taken instead of the usual activated carbon black. The dose will be slightly less. Reserve dose white carbon is 10-15 tablets per day. Previously it may be ground and mixed with warm water.
Prevention hangover with activated charcoal
Activated carbon is used not only to facilitate the hangover, but also to prevent it. To do this, it is taken before the planned event. While in the body, means capable of neutralizing the ethanol before it enters the bloodstream. This enzyme helps the body system to cope with the processing of alcohol.
To prevent a hangover, activated carbon drink at least 3 hours before the planned use of alcohol in an amount of 5 tablets. Next, take another 2 tablets after 2 hours and 1 right before the meal.
To enhance the therapeutic effect of the drug in the prevention of hangover is recommended to use a table fat and hot dishes. This prevents the absorption of ethanol by helping to neutralize the drug greater amounts of alcohol and greatly reduce its toxic effects on the body.
The use of carbonated beverages, by contrast, decreases the efficiency of activated carbon. Carbon dioxide contained therein, prevents neutralization of ethanol preparation, as well as adsorbed to the surface means. Moreover, carbonated beverages that are used in conjunction with alcohol, contribute to a more rapid onset of intoxication, and sweet water can aggravate for hangover.
Release forms and synonyms
Activated carbon is available in tablet and capsule forms. If hangover is possible to apply any of them.
Pills
activated charcoal tablets produced in paper or plastic blisters, 10 or 20 pieces in a box or without it. The dosage of the drug is 250 mg.
capsules
Also, means is produced in the form of gelatin capsules. Inside them is activated carbon substance at dosages of 110, 220 and 250 mg. To avoid errors in dosing, hangover preferable to acquire the drug in a dosage of 250 mg.
Synonyms
Activated carbon is also available under the following trade names: "Ultra-adsorption", "Sorbeks", "Karbopekt", "Karbosorb".
Advantages and disadvantages of activated carbon with a hangover
Activated carbon has several advantages in treating hangovers over other means. Unlike many pharmaceutical drugs, it does not just relieves the symptoms of this condition and eliminates the root cause of the syndrome by removing acetaldehyde from the body.
It is also an advantage of activated carbon include:
- Security. Activated carbon is produced from natural materials. Therefore, it can seldom trigger the development of allergy. Means is biotransformation in the body, displayed in its original form, with no residue and does not have a systemic impact.
- Efficiency. The drug quickly enough and effectively helps with hangovers, removing its characteristic symptoms within 2 hours after ingestion.
- Availability. Activated carbon refers to the OTC and is available in almost every drugstore. In addition, it is low cost.
- The possibility of using for prevention. Activated carbon is capable of preventing the development of a hangover when receiving the advance.
Cons hangover cure Activated carbon
The disadvantage of activated carbon provides it with the ability to output toxins useful substances from the body. Also, with regular use of the drug can disrupt normal intestinal microflora composition, because of what can happen disorder chair.
Despite the large range of products from a hangover, activated carbon is one of the most purchased drugs for the treatment of this condition. Its efficacy and safety tested by time. But, even with this tool at hand, it is worth remembering that regular alcohol consumption extremely negative impact on the status of many organ systems and can lead to serious effects.
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