For the treatment of many infectious diseases antibacterial drugs used in medicine. Among the most popular of these drugs antibiotics complex action, and thus is known Tsiprolet. Treatment with this agent should be strictly controlled and the therapist does not conflict with the attached instructions.
The content of the article:
- 1 Why do I need Tsiprolet
- 2 Composition tsiprolet
- 3 In what form is available Tsiprolet
- 4 Pharmacodynamics tsiprolet
- 5 Pharmacokinetics tsiprolet
-
6 Application tsiprolet
- 6.1 For children up to 18 years
- 6.2 adult
- 6.3 For pregnant
- 6.4 for elderly
- 7 Contraindications
- 8 Overdose
- 9 Side effects tsiprolet
- 10 special instructions
- 11 Tsiprolet combination with other drugs
- 12 Conditions and terms tsiprolet
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13 Conditions of supply of pharmacies tsiprolet
- 13.1 analogs tsiprolet
- 14 Videos about tsiprolet
Why do I need Tsiprolet
Tsiprolet - is an antibiotic drug in a new generation. It is intended for the treatment of infectious pathologies which occur when ingested bacteria incapable of live and reproduce in the presence of ciprofloxacin. This substance is able to slow down the movement of micro-organisms and to create a special environment for them ruinous.
Means prescribed in the presence of inflammation, abscesses, and for the prevention of infection.
The direct testimony include:
- bronchitis;
- otitis;
- sinusitis;
- cystic fibrosis;
- pneumonia;
- bronchiectasis;
- obstructive lung tissue;
- tonsillitis;
- mastoiditis;
- pharyngitis;
- sinusitis;
- salmonellosis;
- phlegmon;
- peritonitis;
- pyelonephritis;
- tubular abscesses;
- salpingitis;
- cystitis;
- pyelitis;
- cholera;
- oophoritis;
- chlamydia;
- inflammation of the fallopian tubes;
- prostatitis;
- burns;
- the postoperative period;
- ulcerative lesions;
- deep wounds;
- gonorrhea;
- campylobacteriosis;
- abscesses in the abdominal cavity;
- sepsis;
- arthritis;
- typhoid fever;
- osteomyelitis;
- septic arthritis;
- conjunctivitis;
- barley;
- blepharitis;
- inflammation of hair growth points;
- enterobakterioz;
- gallbladder disease and excretory ducts;
- neutropenia therapy;
- gonorrhea;
- glomerunefrit;
- infections of dental tissue and gums;
- orchitis;
- epidimit and so on.
Sinusitis
Tsiprolet used in case of confirmed bacterial infections sowing all body systems, which tend to flow from inflammation in suppurative.
Effectively on:
- Neisseria gonorrhoeae;
- streptococci;
- klabsiell;
- enterococci;
- Pseudomonas;
- hemophilic rod;
- Legionella;
- staphylococci;
- brangamell.
staphylococcus
Independently make Tsiprolet strictly prohibited. The therapist or surgeon can designate the drug only after the results of blood tests and urine sowing.
Composition tsiprolet
Tsiprolet - it means related to fluoroquinolones group. These tools are similar to antibiotics, but differ in the composition and have a fully synthetic origin. Thus, as an active ingredient in the vehicle is used Tsiprolet substance - ciprofloxacin.
It is a potent cyclic agent whose structure contains a fluoro group and a cyclic piperazine - a substance containing ammonia.
The specified as additional connections:
- hydrochloric acid;
- benzalkonium chloride;
- sodium chloride;
- water;
- Trilon B.
tsiprolet
The composition of the tablet formulation also includes:
- potato starch;
- silica;
- sterinovokisly magnesium;
- talc;
- polysaccharides;
- Tween 80;
- dimethicone;
- Valium;
- titanium oxide.
In what form is available Tsiprolet
Tsiprolet, instruction manual which contains information about several outlet formats, is made in the form of:
- Ophthalmic drops for the therapy of diseases with ciprofloxacin content of 3 mg / ml. They are packed in a bottle with a pipette, 5 ml capacity.
- Infusion solution with active ingredient concentration of 2 mg / ml. This type of means is packaged in a glass bottle with a capacity of 100 ml.
- Tablets with a content of substances 250 and 500 mg. They are packed in blisters of 10 pieces. each.
The average cost of the drug:
| Type of funds | Price pharmacies rubles. | |||||
| Dialogue | Gorzdrav | Pharmacy. ru, online pharmacy | Pills. ru, online pharmacy | Zdravsiti | Yuteka | |
| Eye drops | 53,00 | 54,50 | 59,50 | 64,00 | 55,00 | 53,00 |
| 250 mg Tablets | 50,70 | 53,00 | 60,70 | 64,00 | 55,00 | 51,00 |
| 500 mg Tablets | 105,50 | 99,00 | 109,00 | 106,00 | 106,00 | 105,00 |
| Solution for infusion | 76,00 | 71,50 | 77,60 | 70,00 | 73,50 | 61,00 |
Pharmacodynamics tsiprolet
Means Tsiprolet relates to a fluorine-containing second-generation drugs, providing strong anaerobic, antimicrobial and blocking action on pathogenic microorganisms.
Contained in the composition of the drug ingredients affect the bacilli cell structure, changing the structure of topoisomerase - DNA department, which is responsible for the ability to reproduce. Ciprofloxacin antibiotic creates an environment that is not suitable for living pathogenic bacteria. Under its influence stops protein synthesis in cells of microorganisms in the-division stages of reproduction and dormancy.
Tsiprolet effectively fights with microorganisms from the groups of Gram-negative and Gram-positive bacteria:
- indolpolozhitelny indolotritsatelny and Proteus;
- salmonella;
- Klebsiella;
- E. coli;
- tsitrobakter;
- Enterobacter;
- Shigella;
- edvarsiella;
- Brucella;
- chlamydia;
- Serratia;
- hafnium;
- Providencia;
- Pseudomonas aeruginosa;
- aeromonads;
- Pasteurella;
- Haemophilus bacterium;
- pseudomonas;
- Listeria;
- Morganella;
- aureus;
- Campylobacter;
- pleziomonada;
- Yersinia;
- legionella;
- Moraxella;
- vibrio;
- Corynebacterium;
- Streptococcus agalactia;
- atsinetobakter;
- branhamella;
- Neisser.
Effective means Tsiprolet component also destroys microbial cells, which stimulate the production of enzymes which neutralize the action of other antibiotics, such as penicillin.
Unstable susceptibility to the base material have bacteria:
- gardnerella;
- Mycobacterium fortuitum;
- hrizeobakteriya;
- Streptococcus viridans;
- Streptococcus faecalis;
- Streptococcus piogenes;
- Streptococcus pneumonia;
- Mycoplasma hominis;
- alkaligenes;
- tubercle bacillus.
tubercle bacillus
Tsiprolet, instruction manual which contains information on the susceptibility of microorganisms to be ineffective with regard to:
- Streptococcus fetsium;
- ureaplasmas urealitikum;
- nokardii asteroides;
- peptokokki;
- peptostreptokokkov;
- bacteroides;
- pale treptonemy;
- mushrooms;
- yeast.
Prolonged or repeated Tsiprolet reception means, microorganisms may partially develop resistance to the active substance. The drug has no effect on the microflora of the vagina and intestine.
Pharmacokinetics tsiprolet
The main component means is absorbed at a sufficient rate to 80% of the total content of the dose. The maximum number of active ingredients is achieved after 1 or 1.5 hours after administration tsiprolet. In the bloodstream ciprofloxacin uniformly distributed in volume to 3 liters per 1 kg of body weight. It can to a small extent bind to protein molecules in the blood.
The active substance is actively penetrates cell membranes and enters the tissues of infected organs.
After 1.5-2 hr, its concentration therein is greater than the concentration in the blood. Launch vehicle components takes place through the urinary system, primarily through the kidneys. The residence time in the blood stream - 3-5 hours. Some of the substances are also excreted in the bile or gut.
Application tsiprolet
Since Tsiprolet is a synthetic antibacterial agent, it is recommended not to exceed the specified dosage.
For children up to 18 years
In pediatrics the tool is not applicable, as high risk of rickets, scoliosis or arthritis. The decision on admission tsiprolet children should only be a pediatrician, when the risk of death is greater than the risk of complications.
In identifying Pseudomonas aeruginosa for children 5-17 years old are encouraged to apply 20 mg of ciprofloxacin per kg body weight 2 times a day. The maximum daily dose-1.5 g Duration - up to 2 weeks. When anthrax therapy: 15 mg ciprofloxacin per kilogram of body weight, 2 times a day. The maximum daily dose - 1 year Duration of reception - 8 weeks.
adult
In the absence of special expert guidance is recommended that the standard dosage.
Tablet form.
Take medication before a meal with a large volume of liquid. The tablets are not recommended to chew. Dosage: 250 mg 3 times a day. In severe pathologies flow is permitted to increase the single concentration of 500-750 mg.
To confirm the diagnosis, without secondary infections:
- pathology urogenital organs: maximal dosage per day - 1 g, the duration of reception - up to 10 days;
- chancroid, typhoid: ciprofloxacin 500 mg 2 times a day, the reception duration determined by the physician;
- Respiratory infections: 500 mg 2 times a day, in the presence of pneumococci dosage is increased up to 750 mg per 1 reception, the duration of reception - 7 days;
- gonorrhea: 500 mg 1 time;
- gonococcus, chlamydia and mycoplasmosis: 750 mg 2 times a day for 10 days;
- gastroenteritis: 250 mg 2 times a day, the reception duration determined by the physician;
- peritonitis, bacteremia, septicemia: 750 mg 2 times a day, the reception duration determined by the physician;
- infection musculoskeletal and ENT: 500-750 mg twice a day, the reception duration determined by the physician;
- gynecological pathology: 500 mg 2 times a day;
- dental surgery: 250 mg to 2 times a day for 5 days;
- toothache and flux: 250 mg 1 time per day to 5 days
Eye drops.
Tsiprolet as ophthalmic solution can also be used for landfill ears. This method of application is not specified in the instructions for use. In each eye must be drip 2 drops, manipulation can be carried out 6-8 times a day. In severe lesions of the conjunctiva dose was increased to 2 drops every hour.
After apparently feeling better patient dosage is reduced gradually and the total rejection of the drug.
In ulcerative lesions of the corneal tissue: 1 drop every 20 minutes. for 6 hr., then the dose is reduced to 1 drop every 35 minutes. From 2 days: 1 drop every hour. From 3 to day 14: 1 drop every 5 hours. Continued use of the drug should be under the supervision of an ophthalmologist or other means.
The solution for intravenous reference.
Tsiprolet be administered through a vein in the same time each day. Duration of procedure - 30 minutes.
- Osteomyelitis: dose is calculated on the weight of the patient, the duration of administration - 2 months.
- Salmonellosis: 0.2 g to 2 times per day, duration of treatment - 4 weeks.
- Pathology of the respiratory system and urinary organs: 200 mg 2 times a day, the duration of the treatment - 1 week.
- Gonorrhea: 100 mg once.
Scheme therapy other infections depends on the condition of the patient and the severity of the disease.
For pregnant
Tsiprolet means is strictly forbidden to take during gestation, as the studies of the influence on the formation and life of the fetus was conducted.
for elderly
The elderly are allowed to apply Tsiprolet only under strict physician supervision and resolution of other specialists:
- immunologist;
- cardiologist;
- gastroenterologist;
- endocrinologist.
Contraindications
The direct Contraindications tsiprolet include:
- during gestation and lactation;
- Children up to age 18;
- hypersensitivity to ciprofloxacin and the other components;
- encephalopathy;
- violations hematopoiesis processes;
- central nervous system diseases;
- leukemia;
- leukemia;
- receiving tizanidine.
Violation of hematopoiesis - contraindication to the use of
Precautions should take Tsiprolet patients:
- with dysfunction of the kidney;
- in violation of the blood supply to the brain;
- with frequent seizures;
- atherosclerosis;
- with hepatic impairment;
- with renal disease;
- with a high risk of crystalluria;
- with mental disabilities;
- the elderly;
- with frequent seizures.
Overdose
Exceeding the prescribed dose can cause symptoms gain side effects. In case of exceeding the recommended blood concentrations of ciprofloxacin is necessary to render first aid - wash out the stomach and call a physician. In the hospital staff can assign hemodialysis and peritoneal dialysis.
Side effects tsiprolet
Tsiprolet, instructions for use which indicates only the average standard dosage may cause undesirable side effects. They may be in excess of the recommended dosage physician at a wrong calculation of the maximum concentration of ciprofloxacin to the patient or intolerance of the drug components.
Among the common side effects of release:
- nausea;
- increased creatinine;
- diarrhea;
- itching sensation on the skin;
- urinary retention;
- eosinophilia;
- pain in the stomach;
- flatulence;
- vomiting;
- loss of appetite;
- thrombocytopenia;
- migraine;
- dizziness;
- insomnia;
- leukopenia;
- redness of the skin;
- gustatory and olfactory disorders;
- noise in ears;
- weakness;
- hyperglycemia;
- photophobia;
- increased sweating;
- limb tremor;
Side effects tsiprolet
Very rarely recorded:
- tachycardia;
- leukocytosis;
- temperature rise;
- thrombocytosis;
- fainting;
- convulsions;
- arthralgia;
- Angioedema;
- anxiety;
- diplopia;
- hearing loss;
- hromatopsiya;
- depression;
- hemolytic anemia;
- bronchospasm;
- muscle pain;
- tendon injury;
- muscle pain;
- hepatitis;
- nephritis;
- Layella syndrome;
- intracranial pressure;
- anorexia;
- nightmares;
- paralgeziya;
- anaphylactic shock;
- nodular erythema;
- vasculitis;
- granulocytopenia;
- hematuria;
- tenosynovitis;
- lowering blood pressure;
- hallucinations.
special instructions
If necessary, the use of anesthetic drugs on the basis of barbituric acid and its derivatives need to control pressure and heart rate.
Ciprofloxacin may affect the nervous system, reducing the care and speed reaction, so you can not drive a vehicle when used tsiprolet and work with mechanisms. It is strictly forbidden to take medication with alcohol.
Tsiprolet combination with other drugs
Tsiprolet can be taken in parallel with:
- anticoagulants;
- hypoglycemic agents;
- azotsillinom;
- acetylsalicylic acid;
- ceftazidime;
- clindamycin;
- beta-lactams;
- mezlocillin;
- vancomycin;
- metronidazole;
- antacids;
- izoksazolpenitsillinami.
When the reception together with some means must control the blood and the concentration of active components.
These drugs include:
- theophylline;
- cyclosporine;
- warfarin.
cyclosporine
Prohibited co-administration with tsiprolet:
- nonsteroidal antiinflammatories;
- solutions with an acidic or alkaline medium;
- quinolones;
- zinc- and iron-containing agents.
Conditions and terms tsiprolet
The drug should be stored at room temperature protected from direct sunlight. The drug is strictly prohibited to carry frozen and given to children. The shelf life of the tablet form, and the infusion of the solution - 3 Years, ophthalmic drops - 2 years.
After opening the bottle of eye drops product shelf life is reduced to 1 month. Not allowed to use Tsiprolet after the expiration of that period.
Conditions of supply of pharmacies tsiprolet
Tsiprolet instruction manual describes how potent product containing a certain amount of precursors. Therefore, the tool is released only by prescription.
analogs tsiprolet
Direct substitutes tsiprolet composition and mode of action are:
Tsiprinol.
The main component of the preparation is in the form of ciprofloxacin hydrochloride monohydrate.
Tsiprinol is available in several forms:
- solution for intravenous infusion;
- pills;
- concentrate for solution.
| testimony | Contraindications |
|
Carefully:
|
Dosage should be calculated depending on the stage of disease and the patient's weight. The standard formulation used 500 mg 2 times a day.
Tsipro® 500.
The preparation contains as ciprofloxacin hydrochloride monohydrate. It is available only in tablet form.
| testimony | Contraindications |
Infections of microorganisms:
Immunostimulatory therapy and antidepressants. |
Under the supervision of a physician:
|
Tablets Tsipro® 500 intended for oral administration. They can not be deformed. Admission should occur after a meal.
Dosage:
| Pathology | Power | A single dose, mg | The number of administrations per day | Course |
| Genito-urinary system | uncomplicated | 250 | 2 | 1-2 weeks |
| complicated | 500 | |||
| Respiratory organs, joints, skin | uncomplicated | |||
| complicated | 750 | |||
| Sepsis, abscess, pneumonia, osteomyelitis, endocarditis | — | 1-2 months | ||
| Gonorrhea | — | 250 | 1 | — |
Tsipromed.
The active ingredient is ciprofloxacin means in the form gihdrohlorida or lactate. The drug is produced in the form of drops for the eyes and ears.
| Indications for the ophthalmic solution of | Indications ear dropwise | Contraindications |
|
|
Ear drops are not allowed to use in patients under 15 years. |
Dosage:
| Shape tools | Pathology | pathological form | A single dose, drops | The number of applications per day | Course |
| eye drops | Blepharitis, conjunctivitis | — | 1-2 | 4-8 | 1-2 weeks |
| Dacryocystitis, kanalikulit | acute | 1-2 | 6-14 | 1-2 weeks | |
| chronic | 1-2 | 4-8 | |||
| uveitis | — | 1 | 6-12 | 1-2 weeks | |
| keratitis | — | 1 | 6-15 | 2-4 weeks | |
| postoperatively | — | 1-2 | 4-6 | 5-30 days | |
| ear drops | All infectious diseases | — | 5 | 3 | Until complete disappearance of symptoms |
Ciprofloxacin.
As the active ingredient of the drug used gidrohloristy ciprofloxacin.
Means produced in the form of:
- ointment for the eyes;
- concentrate for preparation of infusion solution;
- tablets;
- drops for the eyes and ears.
| Indications for tablets and solutions for administration into a vein | Indications dropwise and ointments | Contraindications |
Infectious diseases:
Immunodeficiency, antidepressant therapy. Surgeries in preparation and rehabilitation. |
|
Ear and eye drops are not used for fungal and viral diseases. |
Dosage:
| Shape tools | Injury and disease | single dose | The number of applications per day | Course |
| Pills | Cystitis | 500 mg | 1 | — |
| Diseases of the reproductive organs and urinary system | Up to 750 mg | 2 | 5-20 days | |
| respiratory disease | ||||
| Gonorrhea | 500 | 1 | — | |
| Joints, bone tissue | Up to 750 mg | 1-2 | 4-8 weeks | |
| Peritonitis | 750 | 2 | — | |
| digestive organs | Up to 750 mg | 5-20 days | ||
| Pulmonary anthrax | 500 | |||
| Osteomyelitis | 500 | 2 | 8 weeks | |
| The solution in the ampoules | Reproductive and urinary systems, joints, bone | Up to 400 mg | 7-10 days | |
| Digestive organs, ears, nose, throat, sepsis, skin | 400 mg | |||
| renal dysfunction | 200 mg | |||
| Drops for eyes and ears | Keratitis, corneal ulcer | 2 drops | 12-24 | From 2 weeks |
| Bacterial eye disease | 1-2 drops | 4 | 1-2 weeks | |
| ear infections | 4 | 1-2 | Up to 10 days | |
| Ointment for the eyes | Blepharitis, keratitis, dacryocystitis | 0.3-0.5 cm ointment | 2-12 | Up to 1 week |
Tsiprolet drug is a potent agent against a large number of pathogenic microorganisms. Before application means must consult a specialist and choose a treatment regimen according to the attached instruction. Independent use of the drug is strictly prohibited, as this may lead to a deterioration in the patient's condition.
Videos about tsiprolet
Reviews of preparation "Tsiprolet":
Author: Anna Shalunova
