Nicorette spray. Reviews smokers doctors. Instructions for use, contraindications, side effects

Nicotine addiction is psychological and physical start. Therefore, a bad habit is so hard to cope on their own. Among the many drugs spray Nikorettte received the greatest popularity.

This is evidenced by the numerous reviews of smokers. Before buying the drug should meet with the features of its action, the methods of application, contraindications and side-effects.

Form release spray Nicorette

Unique and practical form of the drug makes one of the most popular brands. Dosed application helps at any time to use the tool for other purposes. Absorption of the active substances occurs through the mucosa of the oral cavity that provides instant elimination desires to take up the cigarette.

Spray comes in a convenient bottle, which has a small size.

Stylish and compact design allows you to always have it with you. Nicorette represents-nicotine agent used as replacement therapy. Fast delivery of necessary chemicals can shoot withdrawal symptoms in the short term. In severe situations, relief actually happens in seconds.

The composition of the aerosol

The main active ingredient is a medical Nicorette nicotine. The applied liquid is colorless or yellowish shade, with the addition of mint flavor. The bottle is made of a polymeric material, provided with a sprayer. Useful volume of liquid of 13.2 ml. This is enough for 150 doses of the injection. Nicotine substitution in 1 ml contains about 13.6 mg.

pharmacological properties

After using one dose of nicotine occurs within 4-6 seconds distribution throughout the body. First and foremost it reaches the brain. Pharmacokinetic Nicotine is an active substance that is absorbed rapidly through the mucosa.

Drug metabolism occurs primarily in the liver. There oxidation and demethylation of cytochrome P450. As a result cottonine formed as the main metabolite. It is a marker of smoking. Other metabolites are less active and their number is minimal.

Operating principle

This component affects atsitilholinovye receptors. When used in therapeutic doses, its effect increases the release neurotransmitters. This has a direct effect on the heart and the entire circulatory system, as well as alter the metabolic process in the body.

Spray Nicorette reviews smokers describe only the positive side. This is largely due to the absence of significant changes in mental status. The process of formation of epinephrine, dopamine, norepinephrine and serotonin activates the central nervous system, It improves mood, increases physical activity and, most importantly affects the pleasure center in the brain cortex brain.

But it's only in small doses. When a large volume of nicotine intake of CNS depression occurs. This comes amid desentizatsii or decreases receptor sensitivity. Additionally stimulates neuromuscular transmission, which is rather sharply in a short period of time goes into depression.

After application after 20 min. Blood is concentrated to 90% of the released active substance.

The systematic use of spray allows you to control a constant amount of nicotine, which contributes to a significant reduction in withdrawal symptoms. Observed half-life of about 2 hours. Then within 12-15 hours the rest of the chemicals through the kidneys exits as cotinine and the unmodified material.

Indications

In the past, long-term nicotine was used to treat colds, malaria, in the form of a powder with fainting, and as an analgesic and stimulant.

Worldwide research continues with the aim of using it for prevention and treatment of conditions such as:

• herpes zoster;
• nonspecific ulcerative colitis;
• Alzheimer's and Parkinson's disease;
• herpes;
• impaired attention;

Today, this substance is used in the preparation of tobacco control. Nicotine replacement therapy helps less painful to cope with withdrawal symptoms. Regardless of the human condition is always there even in case of temporary or partial refusal from smoking cigarettes.

The main indications are spray Nicorette:

• getting rid of tobacco dependence lactating and pregnant women;
• to reduce the number of cigarettes smoked;
• tobacco substitute safer means;
• as an alternative to cigarettes when it is impossible or lack of desire smoking cessation;
• when withdrawal syndrome;
• in cases of inability to use a conventional cigarette;
• in the treatment of nicotine dependence.

Spray Nicorette, according to many reviews of smokers and physicians significantly reduces the risk of excess weight. The drug helps to keep the appetite moderate, as there is no failure syndrome.

Contraindications

The drug is a medical nicotine is safe and suitable for almost everyone who wants to get rid of a bad habit. However, be aware that if in the past there were serious health problems are chronic the disease currently, it is necessary before using Nicorette always consult with doctor.

Do not use a spray under the following conditions:

• pathologies of the cardiovascular system (angina pectoris, myocardial infarction, severe arrhythmia);
• failure in the functioning of the kidneys and liver;
• disorders of the endocrine system (diabetes);
• problems with the gastrointestinal tract (esophagitis, peptic ulcer disease);
• benign and malignant tumors;
• postoperative period (depending on the volume of surgical intervention);
• severe infections, including the oral cavity;
• dental implants;
• means individual intolerance components.

Spray Nicorette smokers reviews characterize best. Experts point to the high efficacy and safety, even during pregnancy. But in spite of this there is a risk of negative effects on the unborn child. The ideal option is a separate refusal of the habit during pregnancy, and as soon as possible.

Instructions for use, dosage

Use the device simply.

There are some points that are recommended to observe on a mandatory basis:

1. To fill the container. Positioned as close as possible to the nozzle sprays the oral cavity.
2. Make a single press for spraying liquid. It is important at this moment to breathe and try not to get into a jet of the mucous lips and throat.
3. Do not swallow the saliva about 30-40 seconds. This time is enough that the active substance is well absorbed in order to achieve the desired result. It is important not to take food and various liquids 20-30 minutes.

If you are using a new vial, it must first be tested. It is sufficient to make the spraying air is 2-3. When there were fine spray, it means that the device is ready for use. The same manipulation should take place in the event of interruption of application of cylinder more than 2 days.

As for the dosage, there are some nuances, namely:

1. A therapeutic dose is a single injection. Often, a heavy smoker this is not enough to overcome the desire to take up a cigarette. Therefore, a single application of 2 permitted doses. Typically, the interval between the injections is from 30 to 60 minutes. This is enough for the majority of tobacco dependence.
2. During 4 hours allowed to therapeutic doses. The interval may be 30 minutes or 15 min., When doing one injection. A further application is regulated by means of subjective sensations and the desire to smoke a cigarette.
3. The day is allowed no more than 64 doses. Excessive intake of medical nicotine may negatively affect the well-being adult, even a healthy person.

Spray Nicorette (reviews smokers argue that the positive effects depends largely on the proper use of the drug) for those who have decided to say goodbye with the bad habit.

A full course of treatment is 2-3 months. During this period, an additional incentive to give up cigarettes can be psychological counseling and comprehensive support of others. It is important to give yourself a self-installation of the need to quit smoking.

Side effects

Unpleasant actual symptoms may occur when using any medications. Spray Nicorette is no exception. However, all manifestations are mainly related to the so-called withdrawal syndrome.

Since smoking is a bad habit addiction, from which is formed on the psychological and physiological level, its cancellation will always be accompanied by side effects.

Basically, this is expressed as follows:

• bad mood;
• insomnia;
• nervousness;
• constant worries and remorse because of the little things;
• change of heart;
• violation of care and patience;
• dizziness;
• compulsive cough does not pass;
• constipation;
• the sudden appearance of bleeding gums.

Such manifestations gradually cropped. Some ailments remain until the end of the therapeutic course.

Of adverse reactions, the following manifestations:

• nausea;
• belching;
• frequent headaches;
• hiccups;
• irritation of the mucous membranes of the oral cavity and upper respiratory tract;
• changes in taste;
• burning sensation in the vermilion border and directly in the mouth;
• appearance stomatitis;
• profuse sweating;
• impaired consciousness;
• diarrhea;
• salivation;
• stomach pain;
• sore throat.

Confusion, sudden irritation of the mucous membranes, nausea constant or intermittent vomiting indicates the need for immediate treatment to the doctor. As part of the drug is a small amount of ethanol.

So use Nicorette motorists should cautiously. It means sufficiently serious drawback is that with prolonged use it is addictive. Of course, this dependence is less dangerous than regular cigarettes. To weaning passed painlessly should gradually reduce the daily therapeutic dose.

Overdose

Excess intake of nicotine to humans is very dangerous. In certain cases it may even be life threatening. Hazardous dose is 50-60 mg.

Manifestation of poisoning consists of the following symptoms:

• sudden headache;
• nausea and persistent vomiting;
• digestive disorders;
• epigastric pain;
• unexplained weakness;
• changes in the visual analyzer;
• uncharacteristically sweating.

In such manifestations should immediately stop to smoke cigarettes and use the spray. Required outdoor determination, administration of activated charcoal, the hot drink. It needs a good rest and sleep. If there is an abrupt change of heart activity and breathing is required cardiopulmonary resuscitation.

During the reception, Nicorette is not recommended to drink alcohol. This can cause additional intoxicating the body, which in turn will lead to additional side effects. Usually the person has taken alcohol under control not only their behavior, but also desire. As a result, it would be desirable to have a cigarette in a drunken stupor and do it very often.

Severe nicotine poisoning manifested by symptoms such as:

• weakened pulse;
• convulsions;
• respiratory failure and cardiac activity;
• loss of consciousness;
• changing perceptions of taste and smell.

Should be vigilant for the storage of the drug in the house, if you have small children. They are inclined to drag various objects in his mouth. Care should be taken that the child accidentally poisoned. Some dose for an adult is safe enough. As it can be deadly, too, while the child.

Mainly connected with an overdose of a combination with other similar drugs. In addition, problems can arise in people who consumed a small amount of cigarettes in a short period of time.

Interaction

It is known that many drugs must be taken separately. When combined with other drugs primarily allergic reaction may occur, or the absence of a therapeutic effect. Appear serious complications, delayed healing process and sometimes formation of new forms of the disease.

Spray Nicorette reviews smokers describe in a positive way, but he is capable of a short time to increase arterial blood pressure. , Pain similar to angina, and increased heart rate, what narrate. This is especially noticeable if the product is used with other medicines.

According to studies, it has also been found that nicotine is able to enhance the action of adenosine, which in turn leads to the above symptoms.

It should reduce the dosage of drugs such as clozapine, ropinirole, tacrine, theophylline, pentazocine. During the period of quitting it should be at least 6 months. Spray somewhat reduces the rate of elimination of these funds, which inevitably lead to an overdose. During the period of refusal of cigarettes has been a slight increase in plasma levels.

It is not linked to the data treatment with medicines, and is a specific reaction to the refusal of a bad habit. Women who are taking hormonal contraceptives, should be examined by a cardiologist and gynecologist. It is necessary to exclude possible risks combination of 2 drugs.

Specific recommendations will be the following:

1. The combination with alcohol. Doing so in accordance with the instructions and recommendations of doctors categorically unacceptable. Liquor lead to a decrease of sorption of nicotine in the oral cavity. Besides increasing the risk of severe side effects. Allowed only small amounts of alcohol, containing a minimum percentage of alcohol. It should be remembered that the combination of two components such as nicotine and ethanol can lead to increased adverse symptoms of intoxication and negatively affect the general health during sober.
2. Therapy in childhood. Treatment of medical nicotine persons under 18 years of age is contraindicated. However, in some situations, everything is solved individually under medical supervision. Currently, the use of evidence-Nicorette in childhood, no. There is also no information on the possible risks in this population.
3. Pregnancy and lactation. When a woman is in a position that smoking very adversely affects not only her health, but also the future of the child. Spray in this case, does less harm. This is ascertained by studies of breast milk, in which nicotine was significantly lower than in conventional cigarettes. The important point is the absence of factors of passive smoking child. In any case, the habit you must get rid of and Nicorette is only an alternative, but not a safe substitute for cigarettes.

conditions of sale, storage

The drug is released in the pharmacy network without a prescription. It is available in both fixed points of sale and in the Internet - shops. Keep it should be in a cool dark place out of reach of small children, at a temperature above 25 degrees or below zero. Shelf life is set not more than 2 years, after which the reception means is strictly prohibited.

Price spray in Moscow, St. Petersburg, regions

The cost of drugs is constantly changing. It largely depends on the area and distance from the center. However, the drug can be ordered in the online store regardless of where they live.

City, state	The cost of the drug
Moscow	From 950 to 1400 rubles.
St. Petersburg	From 960 to 1230 rubles.
Voronezh and region	From 563 to 645 rubles.
- Rostov-on-Don	From 867 to 995 rubles.
Samara and region	From 987 to 1050 rubles.
Krasnoyarsk region	From 925 to 1167 rubles.
Astrakhan region	From 796 to 998 rubles.
Altai region	From 950 to 1225 rubles.
Novosibirsk	From 870 to 990 rubles.
Ryazan and the region	From 597 to 899 rubles.

Reviews smokers about the drug

If the habit is formed over the years, always with you have a can of saving liquid. Craving for a cigarette is fast, after 3 months of smoking do not want at all. Regular injections help to cope with emotional problems.

You should never put up with a bad habit, even have the experience of smoking for decades. Spray Nicorette really helps, even if smoking is going on for decades, experienced in practice. First, reduced desire and consumption of cigarettes comes to 2-3 per day, and then completely do not want to smoke. We only need to want and everything will turn out.

It is believed that women are more difficult to get rid of many bad habits. This applies to the smoking of cigarettes. But modern pharmaceuticals helps to get rid quickly from this. Just a few injections and a craving for a cigarette out. Nicorette helps even in the most desperate situations, the code to smoke 2 packs a day.

Reviews of specialists and doctors

It is believed that produce sprays against 2 types of smoking. Some fight off cravings to smoke due to give mouth odor, others simply replace cigarettes. In fact it is not. All drugs of this type contain Nicotine replacement and pleasant fragrances. It has the same qualities and spray Nicorette.

Its effectiveness is due to the proper selection and dosing of the percentage of the active substance.

Give up the habit is hard enough. Spray Nicorette is not a tool that will help 100%. It is also important and independent attitude. Formulation greatly reduces the abstinence syndrome. Craving to smoke does not pass once and for all, for this you need a few days of treatment.

If the person smoking is rare and little time, it is enough to dose 1 hour. Completely overcome the urge to smoke with the correct therapy can already 3 weeks and 3 months are beginning to use spray is extremely rare. Due to smoking will always appear halitosis. To cope with it is necessary to completely give up cigarettes.

Nicorette has a pleasant mint flavor, so that the breath is always fresh. Also known as tobacco smoke and its derivatives adversely affect enamel. Spray significantly reduces the desire to take up a cigarette and visibly brightens teeth after 3-4 weeks even yourself.

Very often Spray Nicorette complain that he has not clear burning property. However, after only a few injections that goes. According reviews smokers, such sensations usually occur in people with high sensitivity oral mucosa and gums. Therefore, they should be used in parallel sensitive toothpastes and consult a dentist.

Useful video of spray Nicorette and its effectiveness

Instructions for use Spray Nicorette:

The operating principle spray: