Pharmacology

Drug treatment of chronic pancreatitis

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Pancreatitis is a disease of the pancreas. Its course and, especially, exacerbation - is quite dangerous for the body, which requires immediate effective therapy. Chronic pancreatitis is characterized by changes in stages of the disease from remission to acute phase. The main goal of treatment is to minimize such phases. This can be done solely by following all the advice of the attending physician.

Drug treatment of chronic pancreatitis

Therapy for chronic pancreatitis includes adherence to a specific diet, elimination of pain syndrome, correction of pancreatic insufficiency and prevention of complications. A significant part of the treatment is taken by drugs that have been prescribed by a doctor. Below we will examine the purposes for which certain types of medicines are used, and which means are most effective.

General description of treatment

It is already impossible to cure chronic pancreatitis, but long-term remission can be achieved, due to which the symptomatology will be reduced to a minimum. It is possible to do this only by following all the regulations, including a full range of measures. One of them is the complete exclusion of alcohol, as well as the intake of those drugs that can have a negative effect on the pancreas. These include antibiotics, glucocorticoids, sulfonamides, antidepressants, estrogens, etc. A doctor who watches you will tell you about a specific list of such drugs.

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An important point is the timely prevention of viral diseases that cause pancreatic damage, i.e.viral hepatitis, epidemic parotitis. It should be noted that it is also necessary to treat any diseases of the gastrointestinal tract in time. This is due to multiple possible consequences. Most of the rules and restrictions in the treatment process will depend on the reasons that led to the development of pancreatitis. But one thing remains constant for everyone - it is mandatory to comply with the diet, along with the intake of prescribed medications.

Drugs

Drug treatment of chronic pancreatitis includes the use of cholinic and antispasmodic agents, antacids, H2 blockers, as well as enzyme and anti- enzyme preparations. Specific drugs, their number, dosage are regulated strictly by a doctor. This is due to the fact that with chronic pancreatitis, a lot of drugs are prohibited.

Drug treatment of chronic pancreatitis

Holinopreparations and antispasmodics

Among these drugs, the most common drugs are atropine, papaverine, platyphylline, no-spa, gastropepine. They are used, mainly during periods of exacerbation, and also if there is a danger of such manifestation. In the body they are administered either by oral route( in tablets) or in the form of subcutaneous injections. The latter is used more often for acute pain.

For the same purposes, all known analgesics are used: analgin, paracetamol, baralgin, etc. They are used both in the form of injections and in the form of tablets. Injection is a quick enough remedy to relieve the pain syndrome, which is necessary during the period of exacerbations. Tablets are enough to take 2-3 times a day, when the pain subsides. If they are characterized as rather intense, then it is allowed to use painkillers having a narcotic effect( buprenorphine, tramadol, promedol, etc.).

Antacids

Among the drugs included in this group, it is possible to isolate maalox, phosphalugel, diamond and other mixtures related to alkaline. They are used in the form of a liquid substance. Ambiguity remains the question of the use of antacids in the case of treatment of patients who are characterized by exocrine pancreatic insufficiency. This is due to the fact that antacid combined preparations containing calcium or magnesium significantly reduce the effectiveness of enzyme preparations, which are the main agent in the treatment of exocrine insufficiency.

Drug treatment of chronic pancreatitis

Enzyme Therapy

This type of therapy is the main in the recovery of the pancreas. Enzyme preparations used together with antacids and H2 blockers are used during exacerbation of chronic pancreatitis, when there is also exocrine insufficiency of the pancreas. This medication combination has a positive effect for patients, so it is prescribed quite often. It has already been said about antacids. As for H2-blockers, they are used to relieve a strong pain syndrome. Among them, you can identify such drugs as famotidine, ranitidine, etc.

Enzyme therapy is caused by the need to suppress pancreatic secretion. For these purposes, trypsin, amylase and lipase are necessary. This substance contains the preparation Creon( 8 000 and 25 000).Enzymes also include the following drugs: pancreatin, pankurmen and pancitrat. An important point here is the fact that this type of therapy is prescribed only after the removal of a strong pain syndrome in an acute attack. The weakening of the dyspeptic syndrome( cessation of diarrhea, stabilization of body weight) is considered one of the most important criteria for the effectiveness of the use of enzyme medicines.

Some patients for what to cure and restore the pancreas, must take enzyme preparations for several years. Only for such a long period it is possible to achieve the subsidence of the disease. However, the experience of individual people shows that the acute phase of pancreatitis ceases already in 3-5 weeks after the start of reception of such funds, and complete attenuation of the exacerbation is observed from six months to a year.

Anti-enzyme therapy

In cases where chronic pancreatitis occurs in conjunction with swelling of the gland, so-called anti- enzyme therapy may be prescribed. Its purpose, like the whole treatment, is to restore the functions of the pancreas. To drugs that belong to this group, distinguish gordoks and counterkal. They are administered by an intravenous route through a dropper. One of the main disadvantages of this method of treatment is a rather high probability of allergic reaction. In individual studies, it was observed in 7-10% of cases of use of such injections. In addition, there is a risk of anaphylactic shock. Such data led to limited use of anti- enzyme therapy.

Drug treatment of chronic pancreatitis

It should be noted that quite often the use of pancreatic enzymes becomes one of the most effective ways in the fight against pancreatitis, to cure which seems almost unreal. Complete correction of the pancreas requires an integrated approach. It includes many factors of an individual nature( specific causes of the onset of the disease, peculiarities of its course, the presence or absence of complications, etc.) and general( follow-up appointment of the attending physician, strict adherence to dietary restrictions, timely treatment and treatment of relateddiseases, etc.).Thus, drug treatment is not all that is necessary to cure the patient, but it is definitely not worth neglecting this or other items of therapy.

Phytotherapy

Speaking about the treatment of chronic pancreatitis, we can not say about the use of medicinal plants and herbs for this purpose. Despite the fact that they may not be so effective in their properties, one should not forget about the benefits of phytotherapy for the whole organism. The thing is that the frequent intake of various medications has a negative effect on the liver, which is a filter of the human body. In chronic pancreatitis, medications have to be taken over a long period of time, which can not affect the functioning of the liver.

Among medicinal herbs can be found such that have antispasmodic, hepatoprotective, antimicrobial and antibacterial action. The benefits of decoctions and infusions from such plants are proved by time. It is only necessary to remember the consultation with the doctor, tk.at a pancreatitis and separate grasses due to the properties can appear under an interdiction. But if you select the appropriate species, agree on their reception with the doctor and constantly use, the effect will not keep you waiting. They, of course, will not cure you completely, but they can help to relieve pain, inflammation or restore the liver after intensified medical therapy.

Treatment of chronic pancreatitis is a long and continuous process. For normal life and the absence of exacerbations of the disease will have to take into account a lot and follow a lot of rules. But if you take it seriously, you can avoid a lot of negative consequences and complications.

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