Adapalene cream from wrinkles, acne, dry skin, rosacea, rosacea. Instructions for use, price, reviews, analogues

adapalene - a drug commonly used in the treatment of acne and wrinkles produced in the form of a cream.

Indications

Means, used for a variety of skin problems. The main indications are acne lesions and wrinkles. The active components of the formulation contribute to the proper keratinization of skin cells, that prevents development of inflammatory reactions and prevents clogging the pores.

Stimulation of cells leads to normalization of keratinization process. The process leads to increased tugora and the top layer of skin elasticity. In this connection, the agent is effective against wrinkles.

The drug helps in the fight against the nasolabial folds, pigmentation, atrophy of the skin and muscles. Means prevents premature aging of the skin, prevents the formation of comedones, fights inflammation and acne.

Effect:

• skin rejuvenation;
• fat reduction, allowing to adjust and normalize sebum production processes;
• tugora recovery and elasticity;
• elimination of minor defects, facial wrinkles, blackheads, acne;
• getting rid of pigmentation;
• prevents the formation of free radicals, which prevents the development of excessive dryness and prevents wrinkles;
• eliminating inflammatory reactions;
• restoration of the natural complexion.

It can be used as an independent means, and comprise means caring - masks, emulsions, creams.

Chemical composition

Wrinkle Cream Adapalene is synthesized (synthetic) replacement of vitamin A, but its properties differ.

The chemical composition of the funds include:

• carbomer;
• propylene glycol;
• methylparaben;
• edetate disodium;
• poloxamer;
• phenoxyethanol;
• purified water;
• sodium hydroxide.

Agent has anti-inflammatory effects, stimulates keratinization process, eliminating a variety of skin problems. The active substances act on receptors involved in the processing of retinoic acid, and do not bind with the protein. Such selective action prevents adhesion follicle keratinocytes.

This leads to peeling of the upper skin layer (horny epithelium) and accelerates regeneration. In this case, the process leads to increased sensitivity of the skin to UV radiation. Accelerated actinic epithelial cells leads to further stimulate cell renewal and regeneration processes, which in turn contributes to rejuvenate the skin, remove wrinkles.

In what form is available

The preparation takes several forms and is discharged as a gel or ointment. Available drug in polymer elongated tubes of 15 or '30 Packed in containers of tubes of cardboard. The cream has a smooth consistency white or white with a yellowish tinge.

Slowly absorbed into the skin. Leaves after application of shine. The cost - 450-570 rubles. Gel uniform consistency, liquid, poluproozrachny. Price - from 430 to 650 rubles.

Farmodinamika

The medicament has certain pharmacodynamic properties associated with the action of the main substance. Thus pharmacodynamics depends on the received dosage form.

The therapeutic effect of the drug observed after 7-14 days of treatment. However, persistent effectiveness means showing after 8-12 weeks of therapy.

Pharmacokinetics

The medicament has low absorption capacity. According to clinical studies with daily use of the cream at 0.1% level of substances in the organism was detected in minor amounts. Metabolites derived primarily by the liver.

Clinical studies in animals have confirmed the minimal risks of tumorigenicity of the drug in conjunction with ultraviolet light or sunlight. Revealed no genotoxic or mutagenic properties of the cream. Also, the drug has no negative effect on the reproductive system.

application

The means used according to indications. The dosage depends on the severity of the pathological process.

Recommendations for use:

1. Before applying means need necessarily to carry out cleaning of the skin from contamination and makeup.
2. It should be a little steam the face with a warm towel.
3. Remedy is applied to dry skin. In this case must apply the massaging in circular motions.
4. After the drug is necessary to additionally use any moisturizer.

Duration of treatment depends on the extent and depth of wrinkles. On average, the duration of the course is 3 months.

adult

Adapalene cream can be applied at any age starting from 12 years. The dosage in adults is 1 time per day. The medicament may be used as a care cosmetic means and used as a mask peeling or wrinkle. As the mask means used 1 time per week.

When this means is applied to a thin layer on the problem area for 40-50 min., After which the residues are washed off with warm water. application rate - 2-3 months. During treatment possible excessive formation of peeling. Which runs independently. The active period is forbidden to use aggressive cosmetic substance and remove the stratum corneum alone.

For pregnant

During pregnancy, the means applied only with the permission of the attending physician taking into account the potential benefit / risk to the health of the unborn child and mother. However, according to clinical trials cream or gel no toxicity (teratogenicity) feedback. Dosage in this standard - 1 times per day. It is used for 3-10 weeks.

for elderly

Dosage adjustment in the elderly is not required. The drug is applied in a thin layer 1 once a day. The therapeutic effect observed after 1-2 weeks.

Contraindications

A major limitation to the appointment of the drug is the idiosyncrasy of the components that make up. It is noted thinning of the skin and the development of excessive dryness, which leads to additional problems.

Additional contraindications:

• seborrheic dermatitis - When using the cream can only worsen the problem;
• childhood 12 years - does not apply by reason of not fully formed skin;
• eczema - means for application slows down the healing process.

Data on the use of funds for children under 12 years are not available. The use of the cream / gel for removing wrinkles is not necessary. It is also recommended to refrain from using the drug a person prone to allergic reactions.

Overdose

When exceeding the above daily dose in the instruction can be observed in various allergic symptoms as redness, itching, rash, desquamation. Accidental ingestion agents may lead to the same reactions as the oral application of vitamin A.

With the development of signs of overdose is recommended to stop taking the medication and consult a doctor. Perhaps the appointment of symptomatic therapy.

Side effects

Wrinkle Cream means may occasionally lead to various side effects. The degree of symptoms and the symptoms depend on the formulation of adapalene.

Thus, when using lotions noted the development of erythema, desquamation. Excessive dryness of the skin, persistent itching, burning sensation. Very rarely means lead to dermatitis, acne, swelling, changes in skin blooms, eczema.

Side effects (Gel):

• burning sensation;
• redness;
• erythema;
• persistent itching;
• excessive dryness;
• sunburn;
• acne rash.

Development of possible adverse reactions in the first month of the drug, after which the severity and symptomatology decreases significantly. According to clinical studies adverse reactions disappear after cessation of therapy. With the development of adverse effects it is recommended to temporarily stop using the drug and consult a doctor for advice.

drug interactions

The drug is resolved to share other drugs related to antibiotics, benzoyl peroxide. cream efficiency is reduced while the use of various applications in the same period of time and on the same skin area. it is recommended to use drugs at different time intervals in order to achieve therapeutic results.

This will prevent the development of irritation and other undesirable symptoms. Mean mestnorazdrazhayuschee high activity of the drug is recommended to refrain from using any other means having a similar effect. This group includes: abrasive soaps, a variety of detergents, cosmetics and perfumes, especially comprising ethanol.

Extreme care cream administered together with preparations containing sulfur, salicylic acid, resorcinol. With the recent use of such means to refrain from receiving the medicament until such time until all signs of irritation disappear.

special instructions

Adapalene, wrinkle cream is not recommended for use in the presence of erythema and other lesions on the skin until they are healed. When applying the composition to the affected area may experience erythema reinforced negative reactions in the form of irritation.

Also not recommended for the drug in the presence of sunburn, as a means strengthens the skin's sensitivity to UV. It is recommended to wait for the complete healing of wounds.

It is necessary to avoid contact with sunlight or ultraviolet light. If necessary, exposure to the sun should stop taking the money the day before the proposed date. In order to avoid the development of reactions necessary to carry out treatment of the skin with special sunscreen and wear sunglasses.

It should be remembered that the drug may cause various adverse symptoms when exposed to adverse environmental factors - changes in temperature, wind, cold. When applying the composition to avoid direct contact with the cream in the eyes, mucous membranes or lips. If accidental contact is recommended to wash the affected area with warm water.

The gel is recommended for people with normal skin type, as well as increased fat content. The cream is designed for dry and sensitive skin.

In the absence of a therapeutic effect after 8-12 weeks of therapy is necessary to apply to the expert advice.

Conditions and terms

Storing means necessary in a dark place at a temperature no higher than 25 degrees Celsius. The shelf life of cream - 2 years from date of manufacture. Do not use after the expiration date engraved on the packaging.

Conditions of supply of pharmacies

Means available without prescription.

analogs

Adapalene is used only when indicated. However, often it means causes allergic reaction or hypersensitivity effects, and therefore, may be replaced with other medicines. In this case, the selection of the analogue must do a dermatologist or beautician.

Self-replacement can lead to negative reactions on the skin.

name of product	Composition / active substance	Features / characteristics	cost of
Klenzit (gel)	Adapalene, clindamycin	The drug is a local destination in the form of a gel based on adapalene. In addition, the structure includes clindamycin - an antibiotic that prevents the development of pathogenic microflora. The drug exhibits komedonoliticheskoe and anti-inflammatory effect. It is effective in the treatment of acne and other skin blemishes caused by natural processes, as well as the action of bacteria. Limitations to the appointment of the following factors and symptoms: During pregnancy and lactation, the high sensitivity of the composition. Extreme care is used for dermatitis and eczema. The composition is applied 1 time a day at bedtime. Before distribution of the skin should be thoroughly cleaned. Course duration - from 1 to 2 months. OTC is released.	435-620 rub.
Adaklin	adapalene	Dermatologic preparation relating to the group of the retinoids. Active substance promotes elimination of inflammatory manifestations, reduces the intensity the impact of adverse external factors, causing various negative reactions - acne, blackheads, wrinkles. Enhances processes keratinization facilitates removal of the stratum corneum. Eliminates wrinkles, preventing the formation of acne. Black dots. Tightens facial contours, and Bor with atrophic age-related changes. The composition is applied 1 time a day at night before going to bed. Duration of protection - from 4 to 8 weeks. Medication is contraindicated during pregnancy and lactation, in children younger than 12 years, in case of hypersensitivity to the composition. Do not apply the cream in the presence of wound surfaces, dermatitis or eczema.	from 459 to 938 rubles.
Differin	adapalene	Medication local destination, produced in the form of a gel or cream. Exhibits anti-inflammatory and komedoniliticheskoe action. Prescribed in the presence of acne, inflammation and greasy skin. It can be administered in combination therapy with other wrinkles and atrophic changes of the skin. The main ingredient helps to alleviate the process of natural removal of the horny layer of the skin. Also medication effectively treats fine wrinkles and other cosmetic defects - comedones, pimples, blackheads. Distributed composition of the subject area 1 time per day. Duration of treatment - 4-8 weeks. However, consistent results are observed when using means not less than 3 months. Contraindications: pregnancy, allergic reactions, dermatitis and eczema. OTC is released. Shelf life - 3 years.	800-900 rub.
Effezel	Benzoyl peroxide, adapalene	The medical agent dispensing in gel form for topical application. Administered in acne therapy, accompanied by the formation of comedones, black dots. It can be used as anti-aging anti-wrinkle, and other minor skin defects. The medicament eliminates the inflammatory manifestations, acne eruptions, fine wrinkles. Restores natural complexion. Lubricate the composition of the problem areas of 1 times a day at bedtime. The course of treatment - 1-2 months. The maximum period of use - no more than 3 months. Restrictions on the assignment are allergic to components, open wounds, pregnancy and lactation. Also not recommended to apply the gel in children under 12 years old. Available without prescription.	from 1012 to 2218 rubles.
Adolat	adapalene	Dermotropic medication produced in the form of a gel suspension. The drug is used in the treatment of acne, small cosmetic defects - blackheads, comedones. It has regenerating action, effectively treats inflammation, suppressing the activity of pathogenic microorganisms. Due to the amplification process, promotes natural removal of the stratum corneum is achieved minor rejuvenating effect. Medicine helps remove fine lines, restore natural complexion. The composition is applied to the affected area 1 time a day at bedtime. The course of treatment is up to 3 months inclusive. The minimum duration of therapy for at least 1 month. Limitations are: pregnancy, breastfeeding, children under 12 years. It is also not recommended to use the gel in the presence of wounds or dermatitis ekzemnogo lesion. Available without a prescription.	from 85 rubles.

Before using Adapalene cream from wrinkles, or its analogues, should consult a dermatologist, and read the instructions on the use of funds carefully.

Video of the cream from wrinkles Adapalene

Adapalene, wrinkle cream, an overview: