Features trimetazidine
This is an old drug that is well-known company "Servier" of France created in the early sixties of the last century. He was the first drug of the group of antioxidants with good effect action. However, the mechanism of action in the body of trimetazidine, a firm created it, found out only after 30 years after the establishment in Mildronate Riga.
Common to these drugs is the same effect on myocardial ischemia with a fireplace. Trimetazidine also allows you to increase physical activity per person. In this capacity, the same action of both drugs. But for patients with angina, doctors prefer to prescribe Trimetazidine, because of the lower doses of the drug required to achieve the same result. While Mildronat more suitable for healthy people who need increased physical activity.
The difference trimetazidine and Mildronate
Mildronat safeguard against cell death during oxygen starvation. This is very important during the recovery of blood circulation in the heart muscle. But the very means of influence on the cells of the heart muscle and Mildronate and Trimezidina different.
The duration of treatment in these preparations vary. Trimetazidine course of treatment is 6 months, and generally designated by treatment Mildronate 6 weeks. It is proved that Mildronat increases the life expectancy of people who have had a severe heart attack.
The combination of trimetazidine and Mildronate
Many medical experts believe that taking Trimetazidine and Mildronat coupled possible. Mildronat affects the rate of metabolic reactions of long chain fatty acids and Trimetazidine affects their disposal. Together they provide improved and stable angina pectoris, and normalization of the body's reaction to the patient exercise.
It is also possible to combine analogue Mildronate Kardionat with trimetazidine. As drugs affecting metabolism mechanism can simultaneously receive and Riboxinum Mildronat. Trimetazidine drink with Mildronate appropriate and considered effective, especially in the postoperative period in patients undergoing coronary artery bypass grafting. Against the background of such treatment quickly increase the protective functions in the cells of the heart muscle. In the same way these drugs work in other types of angioplasty. This means results in improved biochemical indices of human patient.
Compatibility Mildronate and trimetazidine is based on the fact that each of them acts on different parts of the process of metabolism in cardiac cells, and therefore it is possible to reduce the dosage of each. Thus the effect of the total action of drugs increases. Keep in mind that both drugs are classified as low-toxic drugs, and do not give a variety of serious side effects.
Modern cardiologists believe that the energy metabolism in the cells can be improved through:
- ATP consumption reduction cells;
- improving the efficiency of the membrane works in the mitochondria;
- restoring lost links in the chain of respiratory processes in cells;
- reduction in oxygen inquiry cells of the heart muscle.
All this makes cardioprotectors direct Trimetazidine Mildronat and, when used in combination.
sources:
Vidal: https://www.vidal.ru/drugs/mildronate__8897
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = c9ee2b7f-6066-43ea-810d-6d01f53d07bf & t =
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