Components and dosage forms
The active ingredient of the drug wears a similar name - fluconazole. One capsule contains 0.05 g of active ingredient. Also available in the form of tablets of 0.1 g of fluconazole and as a solution for intravenous fluconazole 0.2 g per 100 ml. Packed in 1, 7 or 10 tablets.
Indications
The drug is administered at a candidiasis of any localization, including, for systemic candidiasis. Effective against candidiasis genital lesions, oropharynx, esophagus in chronic atrophic candidiasis. Used in the treatment of tinea and deep endemic fungal infections.
As a prophylactic agent recommended Fluconazole thrush in its chronic form, and for the prevention of fungal infections in patients with severe diseases of internal organs, weaken the immune answer.
effect of the drug
Infectious disease, gynecologists, andrology, and other physicians specializing in the treatment of infectious diseases of the genital tract, Fluconazole administered to drink for thrush, as it shows a pronounced antifungal activity.
The drug selectively inhibits fungal cells, disrupting their multiplication circuit and thereby preventing mycosis. It does not affect the concentration of male and female sex hormones in the treatment within the standard course.
It is shown to be effective not only against fungi Candida family, but also against pathogens intracranial infections and opportunistic mycoses.
Dosing and dosing
The daily dosage of Fluconazole is largely dependent on the degree of spread of the fungus and organ damage because the doctor prescribes treatment, must be calculated in advance and explain to the patient how to take Fluconazole at thrush.
The reception is continued until until laboratory results do not point to a persistent attenuation of fungal infection.
adults
For the treatment of candidemia, invasive Candida infections is used in the first 0.4 hours and 0.2 thereafter. How much drinking at a thrush Fluconazole drug, the physician will decide on the basis of laboratory diagnosis and the selected dose.
In the treatment of thrush oropharynx administered from 0.05 to 0.1 g of fluconazole for one day to two weeks. Therapy may be extended if necessary.
In other lesions of mucosal thrush, excluding urogenital thrush, 0.05-0.1 g administered over a period of two weeks to one month.
Thrush Fluconazole is necessary to take a one-off, the dosage is 0.15 g To prevent a recurrence appoint 0.15 g once a month. The duration of treatment should be between 4 months to a year. Some patients may require more frequent application.
If there is a high risk of systemic infection, taking 0.4 grams a day for two or three days before the probable neutropenia. With respect to skin infections, athlete's foot and skin an effective dosage is 0.15 g The treatment lasts for up to a month.
For the treatment of deep endemic mycosis used from 0.2 to 0.4 grams per day for up to two years. The duration of treatment depends on the type of agent and the depth of the lesion.
Children from 6 years
Children should not drink Fluconazole in dosages higher than the same for adults. When oral mucosal thrush administered 3 mg per kilogram body weight per day. On the first day you can take double the dosage of Fluconazole.
In systemic thrush administered from 6 to 11 mg per kilogram body weight, depending on the severity of the disease. For the prevention of diseases immunosuppressed used standard dosage 3-11 mg per kilogram body weight.
Special patient groups
Patients with impaired renal function when prolonged treatment is recommended fluconazole administration of the first shock, the dosage to 0.4 After administration of such a dosage calculation performed by a physician, with the severity of disease and the level of creatinine clearance.
Adverse reactions
Most often, the following adverse reactions observed in the treatment of thrush Fluconazole:
- headache;
- elevation of liver transferases in blood;
- elevated levels of alkaline phosphatase and bilirubin in the blood;
- change in blood counts;
- allergic reactions.
The digestive tract can meet increasing levels of cholesterol and triglycerides in the blood, digestive problems and vomiting. Hepatobiliary system, in rare cases, jaundice is responsible.
Detect any adverse reactions should consult a health care provider to ensure that the administration of fluconazole scheme is designed correctly.
Overdose
When an accidental overdose Fluconazole need to wash out the stomach immediately. Treatment symptomatic. The drug appears in the urine, because an overdose helps diuresis. Hemodialysis is effective.
Pregnant, nursing, children
The manufacturer does not recommend that women drink during pregnancy FluconazoleExcept in cases where fungal infection is potentially life threatening mother or fetus. It is known that Fluconazole passes into breast milk in the same concentration, which is in the mother's blood, because the use of it during breastfeeding unacceptable.
In need of treatment during lactation is necessary to consider the question of the transfer of the child on artificial feeding or choose another antifungal agent. Orally allowed for children from the age of six.
Features of treatment
Fluconazole treatment of thrush can be started before the results of the cultural survey will be obtained. The product is compatible with some antibiotics, because for complex treatment of thrush.
Fluconazole is effective if
Fluconazole - common drug of thrush in its various manifestations, because in many cases is the drug of choice. According to many reviews, Fluconazole is effective in the treatment of primary thrush. In the case of chronic protracted process, it is effective only in combination with other drugs.
The drug is well compatible with azithromycin and certain other antibiotics. This allows you to use it in the treatment of yeast infections, against which developed co-infection requiring antibiotic treatment - a characteristic clinical picture in the secondary thrush.
sources:
Vidal: https://www.vidal.ru/drugs/vero-fluconazole__10369
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = a35154cb-6bbe-4dc2-b8a1-c478d7407760 & t =
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