Fluconazole - Description
fluconazole - an antifungal drug, the triazole class. Stops transformation of lanosterol to ergosterol (basic "building block" of cell membranes of fungi).
Applied orally and intravenously. The drug effect is high in both cases. Absorbed by cells quickly bioavailability of at least 90 percent.
It is indicated for:
- cryptococcosis;
- Candidiasis different etymology and localization (genital mucous membranes, generalized, disseminated and others);
- mycosis of the skin;
- Endemic mycoses;
- Prevention of fungus in people with cancer (with a predisposition to infections).
Contraindication:
- One-time (single) dose ≥400 mg;
- Idiosyncrasy components.
Not compatible: with alcohol, a drug Cisapride.
In most cases, Fluconazole is transferred easily. Rarely have adverse reactions on the part of the digestive system - nausea, vomiting and abdominal discomfort, allergic reactions.
Nail fungus
Fungal infection of the nail, or onychomycosis, is the result of being hit-dermatophyte fungi.
The following symptoms may occur depending on the type of fungus and its originator:
- itching;
- Odors;
- Peeling and dryness of the skin;
- Discomfort, soreness;
- The appearance of small cracks, staining the nail;
- Changing nail color, appearance of bands or spots, at constant thickness and luster of the nail plate;
- Deformation of the nail plate (thickening, warp);
- The withering away of the nail and its separation from the nail place.
Localization of the fungus can be observed from any nail side - on the side, rear, on the side of the free edge or strike fully the entire plate. In terms of the limbs suffer the most feet, at the hands of the fungus is much rarer.
Nail Fungus brings a lot of inconvenience, especially aesthetic - nail defects have to constantly hide. medication at the first symptoms should be chosen correctly for effectiveness and safety.
Treatment uncomplicated cases carried out using external means antifungal orientation (ointments, lotions and solutions). More complex cases require receiving antifungal drugs inside, as the defeat has left deep into the body.
The fungus to take Fluconazole is required for a long time, Therapy may last from several weeks to a couple of years.
Fluconazole in the treatment of nail fungus
Fluconazole is a potent, effective antifungal agent. Is assigned directly physician in the absence of contraindications. Depending on the disease process and condition of the person it is administered as tablets, capsules or by injection.
Important! Use of a dose exceeding the maximum permitted mg faces of side effects (as per instructions).
Help cure starts quickly, actively focusing in the body and attacking fungus. improvements become apparent as the regrowth of healthy nail.
Moreover, Fluconazole is effective even in advanced stages of the disease.
adults
Immediately, Fluconazole treatment scheme is determined only by a qualified person. However, most people appoint a treatment independently.
recommended dosage of 150-300 mg once every week for nail fungus take the drug fluconazole. After some time you will notice a significant improvement in the nail plate. This is not a reason to drop out of treatment. Therapy, as has been said is determined by the physician, and last for several months or years. On average, with the defeat of nails of hands treatment is 6 months, the feet - 12.
Fluconazole is important to drink at a nail fungus is not only noticeable until the external symptoms of the disease. Complete replacement of the infected nail is still no evidence of an absolute cure. For accuracy should be tested for the presence of fungi in the body.
In complex situations, running a doctor can be an appointment Fluconazole 50 mg daily.
children
Children of different ages Fluconazole is appointed for the treatment of nail fungus, and for their prevention.
Max Fluconazole per day should not exceed 400 mg. Drink drug should be once per day.
The drug is administered in a ratio of 6 mg per kg body weight of the child - the first day of treatment. Subsequently the ratio is reduced to 3 mg / kg. Treatment is carried out at least 2 weeks, the duration is determined by the doctor.
Fluconazole is also used in children under one year. In this case the dose is calculated as a ratio of 3 mg / kg, only that the gap is at night, and 48 hours. Children first weeks of life, was prepared in a similar formulation based only interval between doses is increased to 72 hours.
Also, the drug is used to prevent fungal infections in preterm infants with weakened immune systems.
With care prescribe a treatment of nail fungus with fluconazole for children with chronic diseases of the cardiovascular system, liver and kidneys.
Pregnant and lactating
According to the instructions for use of controlled studies supporting the safety effect of fluconazole on the fetus and the mother's health was conducted.
Absolutely contraindicated in this drug in the first trimester. In the second trimester, when there is a rapid development of all internal organs and systems of reception is also not desirable, the medication may adversely affect the formation of the baby body.
In the third trimester is possible to treat a fungus with fluconazole, in a very rare and severe cases. When the defeat of the fungus becomes life-threatening mother and baby. The fungus can cause significant harm to the fetus, a fetal abnormalities or cause fetal death.
Nursing mothers are also not recommended to take the drug, as it easily passes into breast milk and is concentrated there.
In any case, the treatment regimen of fluconazole fungus on the nails only appointed doctor. The dosage and duration of admission is decided on an individual basis.
The drug treats a variety of infectious and fungal infection of the mucous membranes, skin and nails. Given the complexity of the treatment of these lesions, to get rid of fungal using Fluconazole may once and for all.
Fluconazole in the treatment of nail fungus is quite popular, however its effectiveness depends on several components:
- Properly selected treatment (dose, frequency of use) and complete following it;
- Age infected;
- The severity of the injury;
- State of the organism as a whole.
Moreover, Fluconazole may be futile, if in addition to nail fungus in a patient:
- There are chronic diseases of different nature;
- A weakened immune system;
- Acute lack of vitamins in the body (avitaminosis).
sources:
Vidal: https://www.vidal.ru/drugs/vero-fluconazole__10369
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = a35154cb-6bbe-4dc2-b8a1-c478d7407760 & t =
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