Fluconazole and metronidazole: compatibility, can we take together

Fluconazole - especially drug

Therapeutic effects of Fluconazole - the result of the activity of the same name the substance in a preparation. As a system mikotikom, Fluconazole is particularly effective in the treatment of infections caused by fungal attack.

Among the indications for receiving funds listed Candidiasis - infection of the skin and mucous membranes of Candida fungus that causes thrush and stomatitis. And since the market offers and other drugs with similar effects, many patients are wondering what the best Metronidazole or fluconazole.

To answer this question, it is necessary to pay attention to the specifics of the mechanism of action of each of the drugs.

Fluconazole is produced in the form of tablets, syrup, capsule, solution for drip or powder for suspension.

Application is simple and accessible. In most cases, the manifestation of such unpleasant symptoms of yeast, such as itching, burning, edema genital and curdled allocation, it is possible to reduce considerably already after the first dose of 300 mg the drug.

The powerful effect of drugs - evidence of the unique properties of Fluconazole.

Action of the active drug substance is expressed as:

• suppressing the production of fungal enzymes necessary for its development;
• increasing the cell membrane permeability of fungi;
• inhibition of reproduction processes of fungal spores;
• Obstacles to access nutrients, which leads to the death of the infection.

Metronidazole And when taken together with fluconazole, the effect of the treatment modality will increase significantly.

Metronidazole - especially drug

Metronidazole called drug on basis of the same active substance, antiparasitic and providing antimicrobial action.

Therapeutic effect of metronidazole due to its property to interact with DNA by cells of pathogenic organisms, to inhibit the production of the nucleic acids necessary for the sustenance.

Among the major indications for use of metronidazole - diseases caused by Trichomonas, dysenteric amoeba, anaerobic and some Gram-positive bacteria, as well as Helicobacter pylori.

Without the use of antifungal agents in the treatment of yeast infections, Metronidazole is ineffective. But if at the same time, together with metronidazole drink Fluconazole, it is possible to enhance the overall effect on the infectious agent.

Metronidazole is produced in the form of tablets, suppositories, ointments, creams, solution for injectable administration. However, to achieve a stable therapeutic result in eliminating candida, it is recommended once a day to light candles metronidazole. While the need to drink tablets occurs only in the case of a particularly severe course of thrush.

Which drug best

A comparison of preparations Fluconazole and Metronidazole, properties of active substances in their composition, as well as the mechanism of action completely different. Furthermore, Metronidazole has no fungicidal activity, however is not effective against fungi.

However, the combination of these drugs in the treatment of thrush is more than justifiedBecause both drugs not only refer to the antibacterial and antifungal pharmacological group, but are imidazole derivatives.

Combination of fluconazole Metronidazole indicated for:

• urogenital trichomoniasis;
• candidiasis of the vagina;
• acute vaginitis.

Similarly with fluconazole action has miconazole. In particular intolerance active ingredient fluconazole, miconazole drug can be replaced, which is also capable of effectively combat fungal lesions of the skin.

Patients with special sensitivity to the components of metronidazole may, without prejudice to the therapeutic result to replace its analogue drug - trihopol.

sources:

Vidal: https://www.vidal.ru/drugs/fluconazole__12803
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = a35154cb-6bbe-4dc2-b8a1-c478d7407760 & t =

Found a bug? Select it and press Ctrl + Enter