The occurrence of stomatitis often associated with viral infections, which can be successfully combated with drugs containing interferon. The article discusses the use of antiviral drugs Viferon with stomatitis: characteristics of drug action, the choice of forms and therapeutic drug dosing regimen.
The causes of and manifestations of stomatitis
Stomatitis called inflammatory disease of the oral mucosa, which may be associated with injury or bacterial, fungal and viral infection.
All forms of the disease often develops in young children due to the insufficient level of local factors of protection at mucosal surfaces. Especially severe ulcerative stomatitis virus, caused by herpes infection.
Development of acute ulcer (canker) stomatitis associated with lesions of herpes virus. In the future, possible recurrence of infection.
Several distinct periods during herpetic stomatitis:
- incubation;
- period precursors disease or prodromal;
- the midst of the disease;
- recovery.
Since the infection until the first signs of disease 2-4 days passes. Characteristically acute onset of the disease, malaise and fever.
The next day there are painful sensations in the mouth, which intensified during the meal. At this time, it develops redness and swelling of the mucous membrane followed by the appearance therein of fine bubbles filled with a transparent liquid. The bubbles are small in size, they can be arranged in groups and merge. They quickly burst and form erosion - the surface of the mucous membrane defects, which greatly hurt. Most often, the erosion in stomatitis located in the sky and the lips.
The disease often has a favorable course and prognosis, but was significantly disturbed general condition, as complete clinical recovery is long and occurs within 1 - 3 weeks. During this time, the erosion heal, scars are formed. Rarely observed the formation of deep ulcers, healing for a long time because of the accession of a secondary infection.
The disease may be mild, moderate and severe forms. They are differentiated by the vastness of mucosal lesions and the severity of the general symptoms.
Interferon against the herpes virus
The drug has no direct antiviral action, and does not affect the process of formation of new viral particles in infected cells. Interferon - a protein compound that changes susceptibility of healthy cells to viral particles. Healthy cells become more resistant to infection.
By increasing the resistance of cells to the virus of the affected area is limited and there is no further infection. Due to this accelerated clearance of the virus, and recovery occurs sooner.
action Viferon
Viferon The drug is produced in three forms for medical use:
- gel;
- ointment;
- candles for insertion into the rectum.
For the treatment of lesions of the mucous membranes are used gel for local action and candles, providing a systemic effect of interferon, equivalent injecting. When stomatitis ointment Viferon not applicable, because it is designed for application to the skin, rather than on the mucosal surface.
Application Viferon in gel form provides a local effect in the zone of application and prevents limitation inflammatory using bubbles until dissection. The depth of penetration of the drug into the tissue is limited, and the gel when applied to the mucosa and can spread washed off with the application area, so the mucous it should be used more frequently than in skin manifestations Herpes.
Using Viferon in rectal suppositories provides interferon into the blood and systemic effects in distant foci of infection, which can be compared with injecting medication.
Viferon used in mild disease, and the average severity of the clinical manifestations of herpes infection.
Features of the application in stomatitis Viferon
Instructions for use Viferon in the form of candles and gel does not specify how to treat stomatitis with interferon, Although a detailed description of the drug with herpetic lesions of the skin and mucous membranes of the nose and throat.
When stomatitis in children taking the gel Viferon you want to share using the system antiherpetic drug. Acyclovir is generally used, the drug is administered in tablet form.
Viferon herpetic stomatitis when administered in the same doses, as with any other localization herpetic inflammatory process.
Candles are introduced at an acute infection in an adult daily dose of 2000000 IU after 12 hours duration of application of 5 days. A single dose of the drug for a child under 7 years is 150,000 IU, suppositories are administered within a day twice, duration of the course of treatment recommended by the manufacturer of the drug, is 5 days. If necessary, your doctor may prescribe a longer course of therapy.
Viferon gel is applied in the complex therapy of acute aphthous stomatitis in 5-6 days. A single dose of the gel at stomatitis is a strip in half a centimeter in length. The drug applied to the skin surface with a spatula or cotton swab 3-5 times a day after meals and perform other procedures. After application of the gel necessary for one hour to refrain from eating and drinking.
In recurrent stomatitis suppositories designate adults 10- day course, if necessary, the duration of the drug increases. Gel Viferon these patients are used for 3-4 weeks to 5 applications per day during the first week of treatment in the future - 2-3 times a day.
In case of recurrent stomatitis flow Viferon application must begin at the initial acute stage, before the eruption.
conclusion
Viral thrush - a form of herpes infection that can be treated with interferon drugs in complex regimens. Optimal treatment with interferon stomatitis achieved by means of the combined use of systemic and topical in the form of suppositories and gels.
In most cases, particularly in the presence of relapse, treatment is desirable to supplement the use of acyclovir formulations.
sources:
Vidal: https://www.vidal.ru/drugs/viferon__17497
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 17d123e0-c99e-43c1-a653-197cf507d7a0 & t =
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