dexamethasone - hormonal drug belonging to the group of glucocorticoids. In the human body, it has a marked anti-inflammatory effect.
Dexamethasone in the treatment of lumbar degenerative disc disease
Osteochondrosis of the lumbar injuries accompanied by tissue and spinal discs. It is on this part of the spine accounts for the maximum load during walking and running. When osteochondrosis lumbar vertebrae lose flexibility, the distance between them decreases, fibrotic ring begin to crack. Osteochondrosis causes severe pain in the lower back.
In osteochondrosis of the lumbar Dexamethasone reduces inflammation.
Hormonal agent in the human body as:
- It causes depression PHK;
- inhibits leukotrienes;
- inhibits the protease activity;
- influence in inflammation.
The drug reduces vascular permeability, stabilizes the calcium level in the spine and eliminates degenerative cartilage lesions. Means well eliminate local inflammation and helps to reduce back pain.
Dexamethasone is indispensable in the treatment of osteoarthritis as steroid antiinflammatory agents
. Glucocorticoid reduces the production of certain enzymes that mediate the inflammatory process. As a result of the active drug substance drug people is getting better.Deksametozon used as intramuscular and intravenous injections and droppers. To prepare the sodium chloride solution is used. In some cases, lead Dexamethasone drip. When osteochondrosis recommended to introduce into the soft tissue of 2-6 mg of the drug, into the joints of 2-4 mg. The drug can be used in the treatment of not more than 3 weeks. The maximum dose for an adult patient should not exceed 80 mg.
Dexamethasone in the treatment of cervical degenerative disc disease
When cervical osteochondrosis taking Dexamethasone is necessary to reduce inflammation and associated pain. Cervical osteochondrosis is characterized by degeneration of intervertebral soft pulp into the bone tissue. A sick person feels the periodic severe pain in the neck, the upper back, in the head. Typically cervical osteochondrosis accompanied by dizziness and drop in blood pressure.
Dexamethasone is an effective drug with osteochondrosis inhibits the development of inflammation and eliminate pain. It reduces the degenerative changes of the spine tissues.
In cervical osteochondrosis dexamethasone exerts such effects:
- prevents release of inflammatory mediators;
- restores the sensitivity of receptors;
- inhibits cytokine synthesis;
- stabilizes the calcium absorption;
- It promotes involution of lymphoid tissue.
In cervical osteochondrosis drip medication is administered, intravenously, intramuscularly. Dosage ranges from 2 to 4 mg. The doctor prescribes a dose of the drug, depending on the characteristics of the disease. In the course of treatment it is very important to follow the recommended dosage of dexamethasone and their treatment regimens.
Features of the application
Apply with osteochondrosis drug Dexamethasone is expedient to remove the inflammatory process 2-3 times a day. After three days of drip doctor usually appoints receiving dexamethasone in tablet form.
According to the instructions required to take:
- the first, second and third day - Table 4. in two steps;
- on the fourth day - 2 tablets twice a day;
- for the fifth-sixth day - 1 tablet per day.
In some cases, may cause adverse events by body.
Sometimes there are:
- heart failure;
- hyperglycemia;
- high blood pressure;
- skin lesions;
- exophthalmos;
- depression;
- myopathy;
- increased appetite;
- nausea and vomiting.
In the event of adverse reactions should consult with your doctor about the advisability of receiving dexamethasone in the treatment of degenerative disc disease. Your doctor may prescribe other medicines - Prednisolone, Hydrocortisone, Eufillin.
Contraindications
Treatment to be as effective as possible and did not cause harm, it is required to take into account contraindications to receive dexamethasone in osteochondrosis. Receiving Dexamethasone limited as psychosis, convulsions, myasthenia. When excessively long-term treatment may develop adrenal insufficiency and septic arthritis.
It wants to exclude the use of dexamethasone at:
- pregnancy;
- lactation;
- osteonecrosis tissues;
- glaucoma;
- psychosis;
- osteoporosis;
- AIDS.
Otherwise, you may develop life-threatening complications and irreversible processes. Developing inflammation can lead to tissue necrosis and severe damage to the joints and spine.
Precautionary measures
The use of dexamethasone in the treatment of degenerative disc disease requires compliance with some measures. In appointing the drug is sometimes necessary simultaneous antibiotic therapy. During treatment, doctors advise to manage traffic, because the drug inhibits psychomotor reaction and reduces attention.
You must tell your doctor if there is sudden loss of appetite and loss of muscle mass. This may be due to the effect of glucocorticoid hormone. Dexamethasone reduces the effect of phospholipase and accelerates the catabolism of protein compounds. Dexamethasone can also exacerbate the flow of hidden fungal infection in the body. In the presence of infection should not use dexamethasone in the treatment of degenerative disc disease.
Medium and high dose dexamethasone can increase blood pressure in the vessels. It will certainly be taken into account in the appointment of the drug during the treatment of degenerative disc disease. It is also possible increased excretion of calcium from the body.
Dexamethasone take only an exacerbation of degenerative disc disease. When, after the treatment measures taken osteochondrosis goes into remission administering medicines into the body is stopped. Sick person is transferred to a secondary therapy that is designed to provide further flexibility of the spine and the inhibition of inflammation. To the pathological process is not amplified, it is required to constantly monitor the condition of the pulp spinal discs and cartilage. It is crucial to carry out the necessary diagnostic.
sources:
Vidal: https://www.vidal.ru/drugs/dexamethasone__36873
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 5db6dfe2-5236-4cd7-86de-d6f534373dd4 & t =
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