Antibiotics and alcohol are incompatible, so shortly before the events associated with the use of alcohol, People undergoing treatment begins to be interested in: how many excreted from the body Ceftriaxone. To answer the question you need to consider, through which authorities displayed Ceftriaxone and that can affect the rate of elimination of the active ingredients of the drug.
Pharmacological influence
After administration Ceftriaxone following occurs:
- maximum concentration of active ingredient in the blood product is noted after one hour following intravenous injection, and after 2-3 hours - after intramuscular;
- Ceftriaxone with blood enters the focus of inflammation, but the antibacterial effect are subject to all the tissues of the body;
- half-life of the medicament takes hours, during which time Ceftriaxone partially excreted and requires repeated reception drug to maintain the therapeutic effect.
The instructions for use indicated that active metabolites Ceftriaxone is excreted with urine and partially with bile. The process of complete elimination of the antibiotic from the organs and tissues takes place 2 days after the last injection Ceftriaxone.
What affects excretion
It is not always the time of excretion of Ceftriaxone takes two days, sometimes this period is up to 8 days.
In fact, the rate at which drug will be displayed, influences:
- The duration of the treatment course. After one day, there is a partial elimination of the drug, and the additional administration Ceftriaxone increases in blood and tissue concentration of the drug. The usual course of treatment is 7-10 days, but, according to indications, treatment can last for a month. Duration of drug effect at the time of withdrawal: if you drink Ceftriaxone month, then it will be displayed for about a week;
- Age. The younger the person is, the slower rate of excretion. In young children Ceftriaxone is excreted from the body within 6-8 days. Often prolongation removal of medication components observed in the elderly due to slowing of metabolic processes;
- The state of the urinary system. If there is a renal disease associated with impaired synthetic urine, the drug appears slower;
- liver disease. Since bile Ceftriaxone is displayed in a small amount, but the organ pathology contribute to the accumulation of antibiotic in the tissues, slowing down the excretion.
How long will output an antibiotic from the body depends on many factors, but if you have liver and kidney disease, or course therapy was long, it should not be less than a week after the last dose to refrain from use of alcoholic drinks.
If you break the rules
If you drink alcohol before antimicrobial fully bring the body, the patient's condition worsened dramatically.
He will arise:
- nausea and vomiting;
- flatulence;
- dyspepsia;
- pain in the stomach or lower abdomen;
- skin rashes;
- confusion or complete loss of consciousness.
Sometimes while taking alcohol develop such a dangerous condition for life as angioedema or anaphylaxis.
The deterioration being due to the fact that after the intake of alcohol and absorption into the bloodstream occurs reacting active metabolites drug ceftriaxone and ethyl alcohol, which leads to the development of strong intoxication.
On average, Ceftriaxone is completely eliminated from the body within 48 hoursBut before you drink alcohol or to start a course of treatment incompatible with ceftriaxone, it is worth considering other factors. It should be remembered that the liver and kidneys, chronic administration drug elimination is slowed. If you have these factors, before alcohol intake or starting treatment with another drug is better to make a week break.
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