Appointment and treatment possibilities Ceftriaxone
Treatment of complicated infectious lesions based on the application the maximum effective drugs. The preparation of cephalosporins Ceftriaxone group is recognized as one of the best means for the treatment of diseases caused by Gram-positive and Gram-negative bacteria.
A wide range of activities - a distinctive feature of the pharmacological properties of Ceftriaxone.
The use of appropriate medications for bacterial infections of organs:
- gastrointestinal;
- airway - pneumonia, abscesses, purulent processes in the pleural cavity;
- urogenital area - pyelonephritis, prostatitis, gonorrhea;
- musculoskeletal system - joints, cartilage;
- abdomen - peritonitis;
- laringootorinologii -gorla, nose, throat and ears.
In addition, the use of Ceftriaxone is appropriate for bacterial meningitis, infected wounds and burns, salmonellosis, or Lyme disease, post-operative infections.
In most cases, treatment with ceftriaxone is successful, no complications or adverse reactions. But if you are hypersensitive to the components of the drug can be shown signs of allergy to ceftriaxone. In such situations should be to stop further use of the drug and seek medical advice.
Terms of use of drugs
Ceftriaxone is produced in powder form, which was used for the preparation of injection solution. Injections do and intramuscularly, and intravenously.
Intramuscular Ceftriaxone causes pain, so to prepare a solution as an anesthetic component comprises lidocaine.
Solution for intravenous I Ceftriaxone is prepared from a powder, mixed with sterile water.
Furthermore, it is possible to use the drug drip. In this case, a solution for intravenous infusion is prepared on the basis of special liquids, the composition of which contains sodium chloride, glucose, and other similar components.
The drug is intended for the treatment of not only adults but also children, provided that an allergic reaction to ceftriaxone in a child missing.
The daily dose of the drug for adults is 2 -4 g injections are carried out twice a day with a break of 12 hours. For newborns dosing regimen is calculated by the attending physician, the child's weight, respectively. Children weighing more than 50 kg, the dosage of administered agent adult.
Duration and magnitude of a single dose may vary, depending on the severity of the disease.
Adverse reactions
Due to the individual characteristics of the organism, individual patients Ceftriaxone may be poorly tolerated. On the development side effects indicates a violation of the digestive tract, urinary tract dysfunction, changes in blood clotting processes, and the emergence of allergies.
In addition, side reactions may occur at the injection site - hematoma, abscess, bleeding from damaged blood vessels, severe pain in the gluteal muscle at the injection site.
How does an allergy to ceftriaxone
To ceftriaxone treatment did not lead to complications and serious consequences for the health, it is necessary to control the appearance of any adverse reactions after receiving the injection.
Most often, the symptoms of an allergy to ceftriaxone appear as:
- skin rash all over the body;
- coughing, sneezing, lacrimation;
- pruritus or burning sensation in various parts of the body including the injection site;
- analysis of changes in blood parameters - increasing the number of leukocytes and platelets, impaired clotting parameters;
- inflamed areas of red color;
- dermatitis with the advent of highly itchy blisters;
- fever with a temporary increase in temperature;
- edema, especially at the injection site;
- anaphylaxis;
- angioedema;
- frequent urination;
- dysfunctions of the digestive tract - vomiting, diarrhea, loss of appetite;
- yellowing of the skin and sclera.
In addition, the severity of symptoms of allergy is considered to be a general deterioration of health - weakness, dizziness, back pain, change in blood pressure, nausea.
Causes of allergy to ceftriaxone
development of allergy - it is the body's response to the impact of giperallergennyh components in the formulation.
The main cause of the immune response - idiosyncrasy of the active drug substance, Ceftriaxone sodium salt. But it is also possible that the cause of an allergy to ceftriaxone became intolerant of additional components in its composition.
The exact causes of allergies have not been studied. But, as experience shows, allergy often occurs against a background of predisposing factors.
The most potent risk factors include:
- genetic predisposition, the presence of close relatives with allergies;
- chronic diseases that weaken the immune system;
- uncontrolled treatment drugs;
- no diet, unbalanced diet, leading to accumulation of toxins and waste;
- smoking;
- polluted environment;
- diseases of the digestive tract;
- stress.
Characteristically, an allergic reaction to the drug ceftriaxone may occur and within a couple of seconds after the injection, and after a few hours - this depends on the rate of accumulation in the organism antigen. allergy development is only possible against the background of a critical amount of antigen in the blood.
How to recover from the effects of allergies
An important rule to get rid of any allergy is considered to be the elimination of contact with an irritant - allergen that provokes an immune response. That is, you must immediately stop taking Ceftriaxone.
Further actions to better align with the doctorWhich will determine not only how to eliminate an allergic reaction to the drug ceftriaxone, but can be replaced and the medication for continued therapeutic effect on the underlying disease.
To get rid of the effects of an allergy, you must:
- clean the skin,
- normalize respiratory function;
- restore the functionality of the digestive tract;
- get rid of the itching and swelling;
- remove toxins;
- improve overall health;
- strengthen the immune system.
The elimination of the effects of an allergy is appropriate to use all kinds of therapeutic intervention.
Types of drugs to eliminate the effects of an allergy to ceftriaxone
Admission antihistamines (suprastin, loratadine, tavegil), it allows you to quickly get rid of the main symptoms of allergies - to remove swelling and itching, improve breathing, normalize the functioning of the gastrointestinal tract.
Imposition of an ointment (fenistil, panthenol, Actovegin), including hormonal forms of help to stop inflammation of the skin, itching and swelling. To eliminate erythema and urticaria need anti-inflammatory drugs. Severe damage to the epidermis treated with corticosteroids - Advantan, Elokoma.
To exclude the accession of skin infections due to lower activity of the immune system, you may need a course of antibiotic drugs - or levomekol triderm.
In order to accelerate withdrawal from the body of allergens and toxic substances recommended reception sorbents - Enterosgelya, White carbon Polysorb.
Effects and angioneurotic edema, anaphylactic shock eliminate epinephrine via injection and internal receiving diphenhydramine and prednisolone.
Also shown bracing means and receiving immunomodulatory drugs based echinacea, ginseng, Chinese magnolia, as well as the use of multivitamin complexes.
Ceftriaxone than you can replace with allergies
To replace Ceftriaxone for allergies, consult your doctor - self-treatment can cause complications. Usually, doctors recommend drugs that have effects on the body similar to ceftriaxone:
- Azaran - a means of cephalosporin. The medicine comes in the form of powder for injection, and rarely causes allergies. The purpose of this drug is appropriate at a low degree of sensitivity to ceftriaxone;
- cefotaxime - cephalosporin antibiotic of the third generation. Characterized ceftriaxone similar pharmacological properties. It applies only in the form of injections.
If allergy symptoms appeared after the use of analogs of Ceftriaxone, this may mean that the antibiotics penicillin and cephalosporin group of patients is contraindicated.
In such cases, prescribed aminoglycosides and macrolides:
- erythromycin - macrolide antibiotic. It is indicated for pathologies of infectious and inflammatory nature, including sexually transmitted diseases. It is not recommended for application in liver diseases;
- amikacin - the medicine of the aminoglycoside. It is used in the form of injections. Effective with infectious lesions of the respiratory tract, urinary tract organs, abdomen and brain.
In most cases, the allergic reaction can be eliminated by replacing Ceftriaxone import analogs. If the disease is mild course, it is preferable to use a tableted form of antibacterial drugs.
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