The drug consists of potassium and magnesium asparginata. Components Panangin promote increased activity of specific enzymes. Aspartate transporter is potassium and magnesium. Because of this ion can penetrate the cell membrane in the form of complex compounds. This action causes the improvement of myocardial metabolism in tissues. This effect stimulates the contractile activity of the heart muscle.
The mechanism of drug action based on the fact that the aspartate is an active carrier of Na and K. Due to such properties, these trace elements show an impact on the work of the majority of enzymes, as well as affect the binding reaction of macromolecules with cellular components. Active ingredients included Pananginum at the molecular level in the process of muscle contraction.
To a state in which reception at Panangin arrhythmia contraindicated, include such states:
- Individual susceptibility to components of the medication.
- kidney failure (both acute and chronic).
- Cardiogenic shock (with systolic pressure lower than 90 mmHg).
- Addison's disease.
Among the adverse reactions is isolated violations of the gastrointestinal tract. Most often experience nausea, diarrhea, vomiting and abdominal pain. Furthermore, there may be weakness, paresthesias, bradycardia, as manifestations of overdose and the maximum permissible concentration of potassium and magnesium.
Arrhythmias and use Panangin
Due to the fact that the drug normalizes the electrolyte balance in the myocardium occurs correction process signaling from the main source potential to the chambers of the heart - the atria and ventricles. Therefore, if you take Panangin for arrhythmia, the result is good.
When the muscle fibers of the myocardium are subjected to stress factors, their operation is disturbed. If arrhythmic drink Panangin Forte, decreases the degree of susceptibility to tissue injury. Thus heart rate decreases, and the cardiac output becomes larger. Thus the effect is explained by using effectiveness Pananginum agent in Arrhythmia type tachycardia when arrythmia, fibrillation and ventricular fibrillation and atria (atrial arrhythmias).
According to the application instructions, Panangin used to treat arrhythmias such as bradycardia not shown. This is due also to the fact that the increase in magnesium and potassium levels in the blood and can provoke gipermagniy- -kaliyemiyu. These minerals have a depressing effect on the process of contraction of muscle fibers of the heart.
Due to the fact that specialists often prescribed drugs magnesium in combination with vitamin B6 (pyridoxine)Also manifests decrease severity transmit excitation signals for nerve fibers. Such effects provoked increase the likelihood of slowing down of the heart.
Reception rules for arrhythmia Pananginum
The medicine should drink according to your doctor's recommendations. Tactics of treatment is chosen after the basic and additional methods of examination. First of all, it's electrocardiogram, ultrasound of the heart. With minor arrhythmias, which is accompanied by a slight increase in heart rate, doctors usually Pananginum 1 tablet three times a day.
Panangin for atrial fibrillation, which is accompanied by an increase in heart rate to 300-700 beats per minute, shall be appointed for three tablets three times a day.
The main feature of the drug is its behavior in the stomach. Once in the acidic environment, dragees Panangin under the influence of gastric juice lose activity. Therefore, the drug should be drunk after meal consumption.
In addition, treatment of the various types of arrhythmias and heart diseases (myocardial insufficiency) accompanied reception Digitalis drugs - glycosides. These tools show a certain toxicity. Panangin therefore indicated for use as adjunctive therapy in congestive heart failure and arrhythmias.
Pananginum applied as a solution to eliminate acute attack arrhythmia. For this purpose the contents of the ampoule in a volume of 10 ml diluted in 20 ml of sodium chloride 0.9% or 5% glucose. Introduction takes place by slow intravenous injection. In addition, it is possible to put a dropper person. To this vial was diluted 1 in 250 ml of isotonic solution (liquid for infusion can also be a glucose concentration of 5%) and poured into a vein drip. Also, some physicians to increase efficiency when arrhythmias may be added to the injectable solution Strofantin and other cardiac glycosides.
Special instructions for patients with arrhythmia, taking Panangin
If necessary, control vehicles and other work requiring concentration, use of drugs allowed. It does not adversely affect the reaction.
Particular caution should be observed by patients who suffer from conditions accompanied by hyperkalemia. It can be a crush injury to the soft tissues, burns, diabetes, hemolysis. Application Panangin during childbearing and breastfeeding is permissible.
Simultaneous treatment with certain medications can cause unwanted effects. For internal use with tetracyclines, iron salts absorption Pananginum with the gastrointestinal tract is significantly inhibited. If the arrhythmia treatment drugs listed above need, the time interval between the receiving means should be at least three hours.
In the case of combined use Pananginum arrhythmia kaliysohranyayuschimi with diuretics, ACE inhibitors, β-blockers observed increased risk of giperkaliyemii. The same effect is observed when supplementation of heparin, cyclosporin and steroidal antiinflammatory agents.
Pananginum helps with arrhythmia in the event that it is accompanied by a decrease in magnesium and potassium. In this case, the drug corrects the lack of ions, restores the natural balance of electrolytes. Only proper treatment can improve the patient's well-being for arrhythmia. The patient should understand the importance of compliance with the doctor's recommendations. Otherwise, the possibility of severe consequences - heart failure, myocardial infarction, cardiomyopathy.
sources:
Vidal: https://www.vidal.ru/drugs/panangin__642
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 247161a5-ab7d-491f-8413-4c3bf3e02b46 & t =
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