Omeprazole and Metronidazole - these drugs are often used for the treatment of gastritis or peptic ulcer. Patients who are not familiar with the pharmacological characteristics of drugs, the question may arise: what is better, metronidazole or omeprazole. For Answer should refer to the action on the body of medicines.
Main characteristics Metronidazole
The drug belongs to the antibiotic nitrofuran series. The active ingredient - metronidazole. Its use for the treatment of gastric disorders is based on the following characteristics of the drug:
- high activity against most anaerobic bacteria;
- the ability to penetrate the blood-tissue barrier and accumulate in biological fluids;
- resistance to the action of hydrochloric acid (metranidazol loses activity under the influence of gastric juices);
- by reaction with pathogens penalized in bacteria and anaerobic respiration causes degidradatsiyu DNA.
Drink the medicine three times a day is necessary to 500 mg for a week.
Antibiotic therapy helps kill Helicobacter pylori, and other pathogens, but has no effect on the secretory function of the stomach. High acidity is irritating, interfering with the healing of erosions and ulcers, so prescribe drinking omeprazole with metronidazole.
Information omeprazole
The medicament referred to as proton pump inhibitors, and contains the active substance - omeprazole. Available drug in a gelatin capsule which dissolves in the duodenum.
After dissolution of the capsule shell takes place as follows:
- the active component is absorbed through the mucosa and into the bloodstream;
- with blood enters the stomach wall;
- He begins to "work" by acting on nerve endings;
- a reduction in hydrochloric acid secretion.
After the decline of secretory activity, decreases acidity and terminate mucosal irritation. Instructions for Use indicates that you need to drink omeprazole once daily in the morning or in the evening. While receiving medicine individually matched with the activity of production of gastric juice (in the daytime or at night).
Features stomach treatment
As can be seen from the descriptions of omeprazole and metronidazole, drugs have different effects on the organism and it is impossible to say which one is better. Despite the fact that the combination of omeprazole and metronidazole is considered one of the main schemes for the treatment of diseases of the stomach, sometimes these drugs are not enough.
They further appointed:
- Antibiotics other groups to enhance the antibacterial effect of metronidazole. Metronidazole is recommended to take in conjunction with omeprazole and clarithromycin or metronidazole drink together, omeprazole and amoxicillin;
- Gastroprotectives for additional protection of the gastric mucosa. Assign to take medications on the basis of bismuth (De-Nol, Vikalin). Gastroprotectives envelop the inner surface of the stomach and thus protected from the influence of hydrochloric acid. Elimination of gastric acid irritations erosions and ulcers accelerates the healing of mucosal damage.
Dosing regimen is chosen individually depending on the nature of the disease, the severity of the mucosal damage and bacterial pathogen species.
Omeprazole with metranidazol complement each other well, but some of the medication can not be a better answer. Metronidazole - destroys harmful bacteria and reduces the acidity of omeprazole and both drugs are needed for the treatment of gastric disorders.
sources:
Vidal: https://www.vidal.ru/drugs/metronidazole__18699
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 34a165f5-cd6a-4420-ac87-4d044867cd64 & t =
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