Components and form of the drug
Duspatalin released in two dosage forms - Tablets and capsules. Per tablet 0.135 g of mebeverine have selective spasmolytic effect. Per capsule - 0.2 g The active substance in the capsules is released slower form of the drug called Duspatalin Retard.
Tablets released in a stack of 10 to 120 pieces, capsules - from 10 to 90 pieces. The forming composition comprises lactose monohydrate tablets, gelatin - capsules.
pharmacological effects
Mebeverin as Myotropic antispasmodic, acts by relaxing the tense muscles of the intestine. Under the effect of spasmolytic spasm and reduced the severity of the pain disappears.
Duspatalin no effect on peristalsis and intestinal motility, because in most cases it does not cause violations of the chair. Able to relax, not only the muscles of the intestine, but the sphincter of Oddi, thus improving the bile outflow. This action allows you to assign it Duspatalin with biliary colic.
Drug absorbed from the gastrointestinal tract into the bloodstream, and then enters the liver. Urinary system output in the form of metabolites. From the time of release and absorption of the drug in blood depends on the duration of its action and speed manifestations efficiency.
Indications for
Duspatalin shown to take in such diseases and conditions:
- cramping muscles of the intestine;
- abdominal cramps;
- irritation of the stomach and intestinal walls;
- dysfunction of the gallbladder;
- Gastrointestinal spasms influenced pancreatic diseases;
- disruption from the gastrointestinal tract with pain clarified etiology.
The drug is indicated during the period of rehabilitation after removal of the gallbladder, as well as for the symptomatic treatment of cramps and discomfort in the intestines and stomach.
Mode of application
Tablets take one three times a day for half an hour before meals. Duration of therapy is typically less than two weeks. Tablets need to drink at least half a glass of water, do not chew.
Take one capsule twice a day before meals. Missed dosage should not take - continue to use the scheme without supplementation.
Are the standard recommended dosages. They can be adjusted by the attending physician, who will take into account the individual characteristics of flow pathologies.
Through many developing effect
Duspatalin starts to operate in half an hour when taken in tablet form. Action mebeverine in the form of capsules begins on an hour and a half after administration. For this reason, pills help for urgent relief of attacks of colic, and capsules are recommended for use during the therapeutic course.
The drug is taken before a meal. When applied together with food or one hour after mealtime manifestations effect significantly delayed.
duration of action
Duration Duspatalin in tablet form - up to four hours. After three hours after applying the half marked excretion of metabolites formed.
The capsules are released more slowly and lasts longer. In capsule form Duspatalin operates for a long time - up to 16 hours. Changing the time of action is possible with functional disorders of the urinary and / or hepatobiliary systems. In this case, you may need a dosage adjustment.
sources:
Vidal: https://www.vidal.ru/drugs/duspatalin__33504
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 55cd07f4-f26a-48af-a082-3bcea9f6d970 & t =
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