Azithromycin is produced in the form of capsules, tablets and crystalline white powder which is easily soluble in water. Using the drug for the treatment of any disease does not hurt to find out which group of antibiotics include azithromycin.
The drug is a derivative of Erythromycin preparation, which was the first in the macrolide group. Azithromycin belongs to a subgroup of azalides, which differ somewhat from the macrolide structure.
Erythromycin began to use in the middle of the last century. He immediately became popular because it has a broader spectrum of activity than the older penicillins. With the opening of the first macrolide Azithromycin has become less applicable.
individual properties
Azithromycin belongs to a group of antibiotics erythromycin series. He actively works on the majority of known bacteria. Together with this preparation has a low toxicity and ability to accumulate in the body.
Individual features associated with antibiotic pharmacokinetic properties. The drug is rapidly absorbed by the gastrointestinal mucosa. After several hours in the blood can be detected maximum concentration of the drug.
The unique ability semisynthetic Azithromycin is slow withdrawal from the body. When compared with other antibiotics, which leave the body through the 10-12 hours, Azithromycin is stored in the tissues in sufficient quantity for the treatment for at least a day.
The half-life is 68 hours substance. Due to this property of the drug is prescribed once a day, in contrast to other antibiotics that should be taken 2-4 times a day.
Indications for use
Azithromycin - an antibiotic erythromycin series with antibacterial and antifungal activity. The drug acts bacteriostatically. That is, not Azithromycin is able to destroy pathogenic micro-organisms, but its action is aimed at stopping the growth and reproduction of bacteria. This result leads to the complete destruction of bacterial colonies.
Azithromycin, like other macrolides, is indicated for the control of the following microorganisms:
- Gram positive and negative bacteria;
- intracellular;
- anaerobes.
These infections provoke the development of respiratory diseases, pneumonia, tonsillitis, sinusitis, genital and intestinal infections. By the same diseases include whooping cough, gonorrhea, chlamydia, syphilis, uretroplazmoz.
Azithromycin relationship to penicillins
Patients often ask: "Azithromycin - a penicillin or not?" Antibiotic Azithromycin - a representative of the macrolide group and is related to backup drugs. It is prescribed only if the patient has idiosyncrasy antibiotic agents penicillin. I.e Azithromycin is not penicillin.
Drug compatibility
Applying for Azithromycin treatment, be sure to take into account the compatibility of the antibiotic drug with other drugs.
Together with azithromycin forbidden to use heparin. This drug helps blood thinners. Also attending physician to notify the current receiving funds from heartburn drugs against cholesterol, antiepileptic drugs, medicines for allergies, fungal infections of some pathologies heart.
Contraindications
Azithromycin Pharmacological group - macrolides. Antibiotics are not prescribed to patients who have a high sensitivity to the drug and macrolides in general. A warning to the use of a kidney and liver failure.
With great caution should be used antibiotic during pregnancy and lactation, and for arrhythmia in children. Prohibited assign means children diagnosed with renal dysfunction and liver, as well as newborn.
sources:
Vidal: https://www.vidal.ru/drugs/azithromycin__24064
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 464b69bc-52b8-420f-a2fd-5160efbe8523 & t =
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