The choice of drug
The choice of antibacterial agent based on:
- possibilities of its impact on the intended disease pathogen;
- properties penetrate and accumulate in the cell tissues of the body;
- data on its safety;
- way of doing and dosing of an antibiotic;
- priced drug.
However, compared Azithromycin and Levofloxacin is difficult. Azithromycin - a drug belonging to the group of macrolides, Levofloxacin - to the group of fluoroquinolones. Despite the fact that the drugs belong to different groups of antibiotics, they are equally widely used in the treatment of many diseases caused by pathogenic microorganisms. Therefore, comparisons of drugs is not always correct.
Sometimes in severe inflammation or complications, to enhance the therapeutic efficiency, your doctor may recommend taking medications "Azithromycin" and "Levofloxacin" at the same time.
Description Azithromycin
azithromycin - a semi-synthetic antibacterial drug bacteriostatic action, belonging to the group of macrolides - azalides. It has a wide spectrum of action.
It is performing well in the treatment of diseases provoked by the development of:
- Neisseria gonorrhoeae;
- streptococci;
- staphylococci;
- spirochetes;
- chlamydia;
- mycoplasma;
- anaerobic microflora;
- ureaplasmas;
- fungal lesions.
A huge number of analogues of the drug have been applied in the treatment of diseases caused by bacterial infections. These include Sumamed, Azitroks, Ecomed, ZI-factor Azimitsin, Sumatrolid soljutab, Zitrotsin, Erythromycin, Clarithromycin, Azithromycin, and many other antibiotics.
However, antimicrobial monotherapy is not always effective. According to clinical studies, azithromycin compatibility with levofloxacin is considered, for example, in the treatment of Legionella infections.
Description of levofloxacin
levofloxacin - antibiotic belonging to the group of fluoroquinolones and possessing broad spectrum bactericidal action. Used in the treatment of infectious and inflammatory pathology caused by infection of susceptible microorganisms to levofloxacin.
Levofloxacin is active against gram-positive and gram-negative microorganisms, anaerobic, and atypical acid-fast bacteria.
This antibiotic is rapidly absorbed in the gastrointestinal tract can easily penetrate into the body tissue cells, reaching peak blood concentrations within 1-2 hours after ingestion. Levofloxacin is compatible with preparations macrolides (azithromycin). The effect of the drug can be reduced by simultaneous administration of medicines that reduce the motility of the gastrointestinal tract.
Depending on the type of disease physicians prescribe medication taken once or twice a day in dosages of 250 or 500 mg, depending on the nature and severity of the infection. To achieve better therapeutic effect (depending on the sensitivity Azithromycin and Levofloxacin: anticipated exciter) administration of drugs may be recommended at the same time.
Treatment regimens and duration of drug administration is determined by the attending physician according to the clinical manifestations of the disease, the patient's condition and the effectiveness of antibiotic therapy.
sources:
Vidal: https://www.vidal.ru/drugs/azithromycin__24064
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 464b69bc-52b8-420f-a2fd-5160efbe8523 & t =
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