Duspatalin: what helps, indications for use

The composition and the active substance

The drug release has several forms, including capsules and tablets. It is in this form is issued the original drug. The capsules have the ability to accumulate in the body due to the high content of the basic substance in a preparation.

Duspatalin pills help from digestive problemsSo they take effect almost immediately. The rate of exposure of some form of release on painful focus depends on the presence in the composition of the dosage form additional elements that accelerate the absorption of the active component.

The basis of any of the dosage form is Duspatalin mebeverine hydrochloride. In tablets, the principal element is the number of 135 mg capsules - less than 200 mg. Additional elements in capsules and tablets separated.

For the tablet form is characterized by consisting of the following elements:

• plant starch (potato);
• talc;
• povidone;
• magnesium stearate.

For capsules:

• triacetin;
• soya lecithin;
• ethyl acrylate;
• titanium dioxide.

Capsular release form provides for a gelatinous sheath, inside which is the active ingredient. The tablets covered with enteric-coated.

The principle of action and pharmacodynamics

Duspatalin indicated for the treatment of diseases of the gastrointestinal tract, so the dosage forms are ingested. Cleavage capsules and tablets occurs in the upper sections of the small intestine. Acid in the stomach may affect the activity of the drug, so the manufacturer has provided special coating formulations shell resistant to acid.

The active substance in the composition is considered Duspatalin miotropnym, so ingestion observed decrease in tone and contractile activity of the muscles of the intestine and stomach. The greatest impact is on the large intestine. Due antispasmodic effect, Duspatalin helps with constipation, speeding up the movement of food through the intestines and preventing the formation of clots. In addition to antispasmodic effect Dyuspatalan able to exert influence on the majority of biochemical processes occurring in the digestive tract.

The mechanism of action is based on Duspatalin ability to relax smooth muscles of the gastrointestinal tract, It acts directly on parts of the colon due to the location there of most cells smooth muscle. Duspatalin not able to exert an anticholinergic effect on the body, but under its influence accelerates the flow of bile from the gall bladder and the sphincter is weakened. Metabolization in the liver, is formed a plurality of active metabolites. Excretion long, is carried by the kidneys after 14-16 hours after a single application.

Application Duspatalin

Duspatalin treats diseases which are often accompanied by spasms of the gastrointestinal tract. Duspatalin taken to eliminate painful sensations after meals and improve waste removal from the body. Duspatalin can help with bowel obstruction and cholecystitis.

The drug is approved for use as a part of treatment of symptomatic character:

• bowel syndrome. Eliminates painful sensations that accompany intestinal disorders.
• Biliary colic. Application permissible in the initial stage of attack.
• Secondary cramps. Medication relieves spasms development of secondary origin in holitsistit and pancreatitis.
• Gall bladder dysfunction. Application Duspatalin allowed after surgery to remove the bladder.
• Functional disorders of the digestive tract. Pathology can be accompanied by severe sharp pains.
• Pain in the stomach. Discomfort may occur against the background of a spasm.
• Colic in the gut. Application Duspatalin in this case is permitted from 12 years.

On the question, Does Duspatalin by excessive gas formation in the digestive tract, the exact answer is no. The medicament may be included in the complex therapy in identifying exact causes of flatulence, especially if excessive formation gas provoking intestinal disorders.

What does not help Duspatalin

The medicament is not assigned in pathologies kidney and liver. Action Duspatalin applies only to the gastrointestinal tract. Duspatalin does not help patients with gastric ulcer and duodenal ulcer with cancer tumors in the stomach and intestines. Polyps in the gastrointestinal tract can not be Duspatalin treatment. The medicine is not used at gastroenterocolitis infectious nature.

Dosage and application of Algorithm

Both medicinal forms are intended for oral administration (orally). Apply Duspatalin according to individually tailored dosing regimen. Medication should be prescribed by a doctor, a separate deduction dosing regimen omitted. Pills and capsules of the blisters need vyschelkivat carefully avoiding deformation tablets. Drink the medicine you need as a whole, is not soluble in liquids and pills without turning into a powder. Wash down Duspatalin necessary a sufficient amount of lukewarm water (70-100 mL).

Strongly and lightly carbonated drinks, strong tea and coffee, dairy products for this purpose are not suitable. They can affect the rate of vapor absorption of the formulation. applying course selected individually, based on the patient's diagnosis. Dosage regimen may also vary in the direction of decreasing / increasing dose.

Intestinal colic Duspatalin recommended to drink for 14 days, three times a day. The patient should take 1 tablet 1-1.5 hours before mealtime. Treatment may end earlier, provided the patient was relieved and noted the absence of pain.

Gall bladder dysfunction require regular doses for 14-21 days. The dosage regimen is selected individually, the maximum number of active substance Duspatalin should not exceed 600 mg. For the convenience of the daily requirement can be divided into several stages.

Irritable Bowel Syndrome requires a longer reception Duspatalin. The drug should drink 4 weeks. It is important to observe the regime of dosing and all other requirements of the attending physician.

In most cases patients Duspatalin administered in the following doses:

• In the first 7 days - take the drug three times a day. In the morning and at lunch you should drink 1 pill before bedtime - 0.5 tablets.
• Second week - to drink the medicine twice a day, 1 tablet once.
• Third week - take Dyuspatalan 2 times a day, in the morning - as a whole, before going to bed - half dose.
• Fourth week - to drink no more than one pill a day, preferably before bedtime.

In order to avoid the development of "withdrawal" Duspatalin must be taken regularly, gradually reducing the dose. Especially it concerns a long-acting capsules.

Contraindications

Like most antispasmodics, Duspatalin has some relative and absolute contra-indications, the presence of which the reception of a medicament for therapeutic and prophylactic purposes It becomes impossible. By absolute include:

• hypersensitivity;
• childhood.
• period of childbearing and breastfeeding.
• individual intolerance of the active ingredient.

Hypersensitive patients are required to immediately notify the doctor about the individual characteristics of the organism. In this case, the specialist will select a more suitable analogue. Precise data on the possible consequences of the application of Duspatalin during pregnancy and lactation is not, so the medication guide prohibits the use of the drug in pregnant or lactating women. For children under 12 years are not allowed use of the drug.

For relative contraindications include the presence of patient pathologies the kidneys and liver. Such patients may require an adjustment of the dosing regimen.

Overdosing and side effects

Characteristic symptoms of an overdose are observed in patients arbitrarily increase the dose prescribed by your doctor.

Symptoms of overdose include:

• uncontrolled vomiting;
• weakness;
• dizziness;
• Angioedema (extremely rare in sensitive mebeverina patients).

First aid overdose is a timely Duspatalin gastric lavage patient. To do this, a person needs to drink 2.5-3 liters of a solution of calcium permanganate. Chelators (activated charcoal) to accelerate the elimination of toxins from the body.

Side effects may occur due to incorrect reception Duspatalin. In most cases, rejection manifested in the form of allergic reactions and dyspepsia. In 19% of patients the side effects may manifest as dizziness, nausea and defecation disorders (diarrhea).

Specific guidance and interaction with other antispasmodics

Duspatalin able to affect psychomotor refleksatsiyu requiring attention. Appointment of drugs in pathologies of the stomach and intestines involves a complete rejection of driving and other vehicles.

Duspatalin not interact with all the drugs. The drug is not compatible with the majority of antispasmodics, their concomitant use is prohibited. Poor interacts with a number of antiviral drugs, so the interval between doses of antiviral drugs and Duspatalin is 10-14 days. Proton pump inhibitors together with antispasmodics may require adjustment of the dosing regimen.

Application Duspatalin carried out as a preventive measure before and after surgery. When partial removal of the gall bladder medication prevents bile to accumulate in the body and accelerates its excretion. During drug rehabilitation supports natural peristalsis of the intestine and prevents the formation of lumps of digested food.

analogs

Using the analogy becomes possible in the event that the patient has the absolute contraindications to the use of the original.

Drugs with similar therapeutic effects:

• Ditsetel. French drug with a similar therapeutic effect to the original. The preparation basis of pinaverium bromide. Sold in pills. Myotropic antispasmodic approved for use in diseases of the gastrointestinal tract, accompanied by cramps.
• No-Spa. Manufacturer analogue Duspatalin -Hungary. Drug means has several major forms of release, including injection, and tablets. Widely known antispasmodic, used in diseases of the biliary tract.
• Trimedat. Structural analogue Duspatalin. The drug controls the motility of the intestinal tract. In its structure there trimubetin.

Duspatalin analogues to be used for medicinal purposes with the permission of your doctor.

findings

Duspatalin is an effective antispasmodic, eliminating pain in the epigastric. The application should be administered under the supervision of a specialist and a well-defined dosing regimen. Before treatment is necessary to carefully read the instructions for use, which defines the possible contraindications and side effects.

sources:

Vidal: https://www.vidal.ru/drugs/duspatalin__33504
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 55cd07f4-f26a-48af-a082-3bcea9f6d970 & t =

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