Duspatalin pain in the gut: how to receive help or not

Duspatalin - pharmacological features

Duspatalin - a drug having an antispasmodic action. It refers to the pharmacological group myotropic antispasmodics.

It is used to relieve symptoms of pain, spasms and intestinal disorders provoked by:

• dysmotility colon mechanisms;
• reduction of intestinal smooth muscle tone;
• irritation of the nerve endings;
• overstretching of the intestinal wall;
• absence of peristalsis, or the appearance rate of pathological character - weakened, strengthened.

The pharmacological characteristics of the drug due to the properties main component of Duspatalin - mebeverina compound. This substance has the ability to direct action on the smooth muscle.

bowel treatment Duspatalin provides a consistent run of several antispasmodic processes:

• intestinal permeability reduction of muscle cells;
• slowing cell membrane depolarization by blocking the entry of calcium and sodium ions;
• obstacle norepinephrine reuptake;
• anesthetic effect;
• relaxation of smooth muscles of the intestine;
• improved absorption of liquids;
• Optimization of intestinal functionality;
• elimination of pain, cramps and colic.

Applying for Duspatalin intestine, gastroenterologists serve two purposes - relief of symptoms and preservation of the natural peristalsis of the digestive tract.

Properties pharmacokinetics Duspatalin

Duspatalin taken orally. Upon receipt, the active compound mebeverine is absorbed by the liver, where during the first-pass hydrolysis decomposes into mebeverinovy ​​veratric acid and alcohol. Duspatalin getting into the bloodstream is not observed.

Conclusion metabolites from the body is during the day - together with bile and urine.

Increasing the dose does not result in accumulation of the drug substance in the patient.

release Form

Duspatalin manufactures company Solvay Pharmaceuticals BV from the Netherlands. In the domestic market pharmaceutical formulation is available in two dosage forms - Duspatalin 135 mg tablets and capsules with high concentration of active ingredient.

One capsule contains 200 mg of mebeverine, thereby, reception means provides a longer action - therapeutic effect achieved is maintained for 16 hours.

Indications for admission

bowel reduction - a natural process necessary for the promotion of gastrointestinal food. Peristaltic waves provide muscle fibers arranged in the walls of the intestine.

The appearance of pathological changes in bowel habits reflected in its peristalsis, reducing or increasing the intensity of the contractions. Spasm, which developed as a result of the prolonged contraction of smooth muscle, called colic.

Duspatalin has a relaxing effect on muscles and its use in intestinal spasms helps to normalize the intensity of contractions, irrespective of the causes of deviations. Therefore, the drug is indicated for the treatment of all types of the gastrointestinal tract and the biliary system, accompanied by spastic pain functional diseases:

• with the syndrome of irritable bowel Duspatalin used in the complex therapy for relief of the symptoms of major diseases;
• when biliary colic, colitis, as well as bowel preparation is not only relieves symptoms, but also optimizes the flow of bile;
• intestinal disorders, soprosvozhdayuschihsya pain, bloating, constipation or diarrhea. Duspatalin diarrhea restores the digestive tract and normalizes the chair.

Furthermore, the preparation helps with pancreatic inflammation, chronic cholecystitis, biliary dyskinesia, at the bend of the gallbladder, with flatulence, as well as in violation of the tone of the sphincter of the gall or pancreatic ducts.

Cramps can also occur against the background of gastroduodenitis and peptic ulcer disease. At therapeutic doses prescribed for gastroenterologists Duspatalin bowel inflammation, as means having the hypotensive, vasodilatory and spasmolytic effect.

A drug:

• predovraschaet development of hypotension intestine tissue;
• relaxes the sphincter of Oddi;
• normalizes the motor-evacuation function of the gastrointestinal tract;
• It eliminates the pain, nausea and flatulence;
• suppresses aggravation of chronic pathologies of the intestine and liver;
• It reduces the level of smooth muscle contraction.

Duspatalin also recommended for use as part of combination therapy for the treatment of complications of peptic ulcer and cholelithiasis.

How to take Duspatalin

Admission Duspatalin indicated in patients from 12 years of age.

Both tablets and capsules are not recommended to chew - to achieve an optimal therapeutic outcome dose is swallowed with plenty of water.

Standard dosage tablet form of the drug is one tablet half an hour before meals - three times a day.

Sustained improvements in patient well-being observed, usually within a week. If the physician finds the desired level of therapeutic effect, the dose is reduced to two times the daily administration.

After another week, the presence of positive results Duspatalin reduce the dose of single dose per day. In some cases, it may decrease to half the dosage of 125 mg tablets.

If after a dose reduction was the return of symptoms, it is recommended to renew the former dosing regimen. Correction of the dosage provides the treating physician, taking into account the patient's condition.

Application of the encapsulated form of the drug

Duspatalin capsule possesses the property of long-term exposure by increasing the amount of the active compound.

Before taking the capsules need to ensure the integrity of its shell - any damage contributes to the rapid penetration of large doses of the active substances into the patient. The result of receiving the opened capsule Duspatalin would be rapid but short-lived improvement in intestinal health because such exposure can not provide a long therapeutic effect.

A standard dose - one capsule half an hour before each meal, but no more than three times a day. The duration of treatment is adjusted physician, depending on the patient's condition.

Contraindication to receiving medications considered idiosyncrasy tools and alcohol. During pregnancy Duspatalin taken with great caution.

Despite the effectiveness of the drug in eliminating symptomatic manifestations of gastrointestinal diseases, Duspatalin is not considered the primary means of treatment and only used to improve the well-being patient. The optimal way to use the therapeutic possibilities of the drug - use Duspatalin in the complex therapy of the intestine.

For relief of pain and spasms in the intestine and drugs used counterparts that are based on connections mebeverina - Spareks, Niaspam, Veremed.

sources:

Vidal: https://www.vidal.ru/drugs/duspatalin__33504
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 55cd07f4-f26a-48af-a082-3bcea9f6d970 & t =

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