What is the composition of the drug
The main active ingredient in the drug acts Enterofuril nifuroxazide. Also included in the medication, such additional ingredients: corn starch, sucrose, cellulose powder, magnesium stearate.
The dosage form of the drug
The preparation is represented by oblong yellow hard gelatin capsules, which are the body and the cap. Capsules filled with granules, which breaks with a slight pressing. Available drug in a dosage of 100 mg and 200 mg.
Also Enterofuril produced as a yellow slurry which was administered to children. It is sold in bottles with the scoop.
Therapeutic
Enterofuril is an antimicrobial agent which is used for treatment of intestinal infections. -Antimikrobnoe effect of the drug, a broad spectrum. Enterofuril identifies antimicrobial effect which is caused by the presence in the composition of NO2-group, which suppresses the dehydrogenase activity and reduces the production of proteins vyrulentnymi microbes. Also Enterofuril is effective in lesions organism Gram-positive microorganisms and gram-negative enterobacteria.
Nifuroxazide no effect on saprophytic flora and does not disturb the intestinal flora. And Enterofuril pills help restore bowel eubioz in acute bacterial diarrhea.
After applying orally Enterofuril practically not absorbed from the gastrointestinal tract and misses in other organs and tissue, 99% of the drug is consumed in the intestinal lumen. Nifuroxazide exchange occurs in the intestines, while 20% of them are excreted unchanged. Nifuroxazide metabolites are excreted in the feces. excretion rate of the drug from the body depends on the amount of funds received and from GI motility. Displayed nifuroxazide slowly and remain in the intestines for a long time.
When receiving a therapeutic dose of the drug suppression of intestinal microflora does not take place, nor does it appear stable forms of the microbe. The therapeutic effect was observed during the first hours of therapy.
Indications
The drug is used in violation of a chair, caused by infectious agents. Enterofuril also helps with acute and chronic diarrheaWhich occurs due to ingestion of the microorganisms which are sensitive to the drug, and is effective for diarrhea of unknown etiology. Yet the drug has an indication for chronic diarrhea in patients who suffer from colitis and iatrogenic diarrhea caused by antimicrobial agents.
Contraindications
It is impossible to treat patients are hypersensitive Enterofurilom formulation ingredients and other means nitrofuran derivatives. Also, the drug is contraindicated for use in children under 1 month, infants who were born before the target date. Enterofiril capsules can not be attributed to children who are under 7 years old.
Use during pregnancy
At the moment, there is insufficient data on the impact of the drug on the woman's body during pregnancy, so use the drug is not recommended without a doctor's prescription. The drug may be administered to a pregnant woman by doctors when the benefit to the mother is higher than the risk to the fetus. And also found that the action on the body is not Enterofuril systemic nature, so it can be used during lactation.
Dosing for children and adults
Before you start treatment Enterofurilom, you must go through a consultation with the specialist. The dose for adults is 200 mg capsules 4 times a day. Use the drug must be up to the complete disappearance of diarrhea. Recently, the use of the drug should be not later than 12 hours after the last act of defecation. Duration of therapy should not be more than seven days.
Appointment capsules Enterofuril children:
- 3-7 years - 200 times mg3;
- child older than 7 years - 200 mg 4 times.
Daily application Enterofuril in suspension children:
- 1 month - six months - 2, 5 ml, 2 times;
- 7 months - 2 years - 2.5 ml of 3 times;
- from 3 to 7 years - 5 ml 3 times;
- older than 7 years - 5 ml of 4 times.
If the patient is not able to be treated Enterofurilom, the doctor prescribes an analogue at a price cheaper than the drug.
drug overdose
Currently no cases of overdosage have been reported. When a drug overdose symptoms is necessary to wash the stomach, take chelators and apply symptomatic therapy.
side effects
In applying Enterofuril may cause temporary pain in the abdomen, nausea, vomiting and diarrhea amplification. And also can develop an allergic reaction, in the form of itching, rashes on the skin, hives, angioedema, and anaphylaxis. When such a reaction of the organism, it is necessary to cancel the medication. Subsequently, the patient should avoid use of funds and analogs, derivatives and nitrofuran those involving nifuroxazide.
Compatibility with other drugs
Since Enterofuril drug has no systemic effect on the body, interactions with other medical action is unlikely. Enterofuril can not be used with medicines that contain alcohol. And it can not be used together with sorbents, as they can reduce the effect of the drug.
Finally, a small
Enterofuril is gastric antbiotikom, so its use must necessarily agree with the doctor. Self-medication can lead to goiter, as with the pathogenic microflora is partially affected and the necessary bacteria.
sources:
Vidal: https://www.vidal.ru/drugs/enterofuryl__2734
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 9c80dbb9-89f9-4129-bbb9-dfdafb9989e7 & t =
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