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Medicine

Excelon plaster - transdermal system for the treatment of Alzheimer's disease

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exelon plaster Despite scientific achievements in the field of medicine, not all diseases affecting the nervous system are amenable to treatment.

There are a number of neurological diseases in which one can only lightly ease the patient's condition and restrain the development of destructive processes occurring in the body. One of such complex neurological abnormalities is Alzheimer's disease.

Since this disease can not be cured completely, the drugs used by modern medicine act only as a deterrent, slowing down the development of the disease. To this group of funds, you can also include the Exelon patch.

Contents

  • What are the advantages of a plaster?
  • Composition and Form of Release
  • Mechanism of Action and Effectiveness
  • Indications and Contraindications for Use
  • Instruction for Use
    • Dosage of Active Ingredient
  • Special Instructions and Patients
  • Side Effects of
  • Opinion of
  • Cost and Analogues of

What are the advantages of a plaster?

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Many people who are forced to constantly take medications in tablets or injections, suffer from problems with the organs of the digestive tract. This is not surprising, since many of the active ingredients that make up the medications, irritate the gastric mucosa and adversely affect the digestive system as a whole.

In such cases, the use of a patch is the best way out. Necessary substances enter the body without affecting the stomach and intestines.

Composition and form of release

Exelon is a white patch with a beige backing in the form of an oval. The surface area of ​​the therapeutic agent can sticker on hand differ, it depends on the amount of the active substance. The transdermal system can be an area:

  • 5 cm( contains 9 mg of the drug);
  • 10 cm( at a dosage of 18 mg);
  • 15 cm( for amount of substance 27 mg).

The main component of the plaster is rivastigmine. This active substance has a beneficial effect on the state of the nervous system and is actively used to treat diseases associated with intellectual and behavioral disorders.

When a patient uses a band-aid, the medicinal formulation gets into the body gradually, in small doses, which allows the active substances to be well absorbed and the risk of overdose is excluded.

The active component of the trans-system is rivastigmine; in addition, the patch contains additional constituents( L-tocopherol, copolymer of acrylic acid, methyl methacrylate and butyl methacrylate).

The adhesive surface consists of a silicone copolymer, L-tocopherol and dimethicone. This composition allows the medication to remain on the skin even after contact with water.

Mechanism of action and efficacy of

Transdermal system The transdermal system acts as follows: once it is attached to the body, rivastigmine gradually begins to enter the body.

The active substance has a beneficial effect on the state of the nervous system. As a result of the application of the remedy, the following positive changes are noted:

  • the state of the cerebral cortex is improved due to the normalization of the processes of producing the necessary substances;
  • slows down the destructive processes;
  • prevents the development of amyloid plaques.

Due to this effect, persistent memory and speech improvements are noticeable in patients with Alzheimer's disease, concentration of attention is observed, and the intensity of behavioral manifestations of the disease decreases. Disappears excitability, tearfulness and forgetfulness, due to which the patient for a long time is able to maintain an adequate state.

Indications and contraindications for use

The main indication for the use of the Excelon patch is Alzheimer's disease in mild or moderate form. Also, the medication can be used for dementia of various genesis.

It is forbidden to use the remedy in the following cases:

  • with increased sensitivity to the components of the drug( rivastigmine and other carbamate derivatives);
  • in case of allergic reactions on the skin that can result from the application of the patch;
  • under the age of 18 years.

Instruction for use

The use of the adhesive is not difficult, it should be used as follows: Plaster on the shoulder

  • wash your hands with soap and if possible, treat them with antiseptic solution;
  • to examine the plaster for integrity, if there are damages on the surface, do not use the product;
  • remove the protective film and attach the patch to the area of ​​the body with a minimal hair cover;
  • fix the product, pressing it with the palm of your hand to the selected body area for 30-60 seconds;
  • re wash your hands.

Remember that the transdermal system should be on the skin within 24 hours, then it must be removed. In addition, the label can not be cut into parts, and also to attach to the skin a new Excel, until the previous one is removed.

Before using the product, you should thoroughly wash your hands, and in case of contact with the eyes, immediately wash them with plenty of water.

Dosage of active ingredient

rivastigmine

Formula of rivastigmine

The initial dose of rivastigmine is 9 mg per day. If the patient normally tolerates the effect of the medication within a month, then subsequently it is possible to gradually increase the dosage in accordance with the recommendations of a specialist.

In case of severe violations it is allowed to increase the dose to 13.3 mg per day, but it needs to be done gradually. To such volume of substance come gradually, before this it is necessary not less than half a year to observe a dosage of 9.5 mg.

However, it should be remembered that as the dose increases, the risk of side effects increases.

Special instructions and patients

There are a number of cases where there is no direct ban on the use of a patch, but the effect of the drug on the body is not fully understood.

So, to observe the precaution in the application of Exelon is necessary for the following categories of patients:

  • in the presence of bronchial asthma and other diseases of the respiratory system;
  • during pregnancy and lactation( if the patch is used during the postpartum period, it is necessary to refuse for the period of treatment from breastfeeding);
  • to persons suffering from diseases of the genitourinary system;
  • in the presence of ulcerative diseases of the stomach and intestines;
  • in cases where the patient suffers from kidney and liver diseases.
In such situations, the slightest deterioration of the condition should immediately stop using the medication and contact your doctor.

Side effects of

The use of a medication can lead to side effects. They manifest themselves as follows: State of anxiety

  • the patient is in a state of anxiety or depression;
  • is impaired cerebral circulation;
  • develops anorexia;
  • there are headaches and extrapyramidal disorders;
  • occur without obvious causes of nausea, vomiting, pain and stomach upset.

As a "local" reaction, you can identify the appearance of swelling, itching, burning or redness on the area of ​​the skin where the patch was attached.

There is an opinion of

Reviews of patients who used Excelon plaster for Alzheimer's treatment.

Bought Exelon for mom, the result was satisfied. Of course, we did not expect a complete cure, but the disease is slowed down. The main thing is to always have plasters in stock, otherwise it again becomes inadequate.

Alina Nikolaevna, 41

Used this remedy at one time, it helped. And then I read the list of side effects, and even people have suggested that he seems to be able to cause hallucinations, and it became terrible. Now I'm sitting and thinking about what to do. I have not experienced any unpleasant phenomena, and it became better, I do not know whether it is worth buying it again or not.

Nina Valerievna, 63

In our family, of course, the case is not an easy one, and we did not expect any tremendous strong effect. But I must say that the disease is not progressing as actively as it used to be, and this is already a big plus.

Toma, 38

Cost and analogues

The price of a medicine depends on such factors as the dosage of the active substance, the number of labels in the package, the manufacturer and others.

Arisept It is most convenient to purchase packages of 30 plasters, in this case the price will range from 3,500 to 4,500 rubles.

It is important to know that in some regions this drug can be obtained free of charge, by presenting a prescription from the treating doctor. Therefore, before you look for Exelon in pharmacies, you need to ask about the possibility of obtaining a free medication.

There are a number of similar drugs that have a similar therapeutic effect. So, you can replace Exelon, using such drugs:

  • Palixide;
  • Nivalin;
  • Arisept;
  • Azazil;
  • of the Gloron SR;
  • Galantamine;
  • Jasnal;
  • Reminiscent.

The listed preparations differ in price both in smaller, and in the big parties or sides.

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