Antimiller hormone, known by the abbreviation AMG, is a substance on which reproductive function largely depends, both in men and women. The level of this hormone in the male body allows you to determine the onset of puberty. The AMH in the blood of women is given special attention, because , it indicates the willingness of the body to conceive and the ability to endure the pregnancy .This substance has an important effect on the functioning of the ovaries, namely it controls the maturation of follicles and their subsequent growth.
Why women are assigned to the test for AMG
Antimulylerov hormone is present in the body of every woman from birth and it dries up only after the onset of menopause. That is, by determining its level, you can find out the number of eggs in the female body, at the time of the study, fully ready for fertilization. Accordingly, this analysis is most often prescribed when standard hormone level tests do not show any abnormalities, but at the same time, having a regular sex life, a woman still does not become pregnant.
A test for the amount of AMG can be prescribed in the following situations:
- to determine the effectiveness of antiandrogen therapy;
- for suspected polycystic ovarian failure;
- in anamnesis there is an unsuccessful attempt of IVF;
- in cases of belated sexual development;
- with infertility with unclear nature;
- for suspicion of a granulosa cell tumor of the ovaries.
Norm of hormone level in a healthy person
When receiving test results, a woman, first of all, needs to understand that this indicator does not depend on external factors such as nutrition and lifestyle. Also, its level in the blood is practically not affected by age, except for the onset of menopause. There are cases when the level of AMH in women after the age of 40 was much higher than in healthy women of reproductive age.
Normally, this hormone in the female body should be contained in the amount of 1-2.5 ng / ml. In cases of deviations, when the indicator is lowered or increased, it appears that there are grounds for assuming pathologies in the female reproductive system.
The results obtained after the AMG study can help in the diagnosis of such female problems as:
- polycystic ovary;
- malignant ovarian tumor;
- infertility;
- earlier onset of menopause.
Increased hormone in the blood
Based on the established norm of the content of this indicator in the blood, antimulylerov hubbub is considered increased when its amount exceeds 2.5 ng / ml. If the deviation is slightly higher than this, then in cases where a woman prepares for an IVF procedure, an adequate excess will only benefit her. This result of the analysis suggests that she has a high chance of pregnancy as a result of artificial insemination.
When AMH in the blood is significantly elevated, it can be perceived as a signal about the presence of various tumors. This may also indicate polycystic ovary, delayed puberty and the presence of a defect in the receptors of luteinizing hormone.
Why does the hormone fall?
In cases where the antimulylerov hormone is lowered, there are suspicions about the presence of the following pathologies:
- ovarian insufficiency;
- reduction of the ovarian reserve;
- the onset of early menopause;
- obesity;
- Premature puberty.
Accordingly, that at a low level of this hormone, an independent pregnancy occurs very rarely. It is necessary to understand that AMG is just an indicator that shows the number of capable eggs.
Artificial stimulation of this indicator by medical preparations, including hormonal ones, is possible. But in this case, the number of oocytes still, unfortunately, will not increase. In fact, the ovarian reserve will remain the same. The indicator of AMH can be increased only if the causes that initially lead to the absence of healthy eggs in the body are eliminated.
Self conception with low AMG
The question of whether it is possible to conceive when an antimulylerov hormone is lowered is quite complex. Critically low test result is less than 0.2 ng / ml. Just a low indicator is usually considered the result of 0.2 to 1 ng / ml.
In the second case, when the figure is reasonably lowered, a control test for FSH is prescribed. If it is not overpriced, the probability of self-conceiving exists. If the hormone is critically low in women, after 30 years old, antimulylerov, this may be a signal of the early onset of menopause.
It is known that the number of eggs that will be ready for fertilization in the future are laid in the female body even during the period of its intrauterine development. At the time of puberty, women, in the absence of serious pathologies, the number of such healthy eggs is about 300 thousand. They are called a female ovarian reserve or reserve.
During each menstrual cycle, several eggs are maturing with the subsequent allocation of the highest quality. This process in the body of a sexually mature woman occurs non-stop, and does not stop even during the reception of contraceptives or pregnancy itself.
Critically low AMH levels in women over 30-40 years of age indicate that the egg stock in her body is coming to a logical conclusion. Unfortunately, in this case, it is already impossible to make the body produce additional eggs.
If the reason for the low rate was the approaching menopause, but the woman wants to get pregnant, in addition to consulting a gynecologist, she needs to contact the endocrinologist. In some cases, the doctor prescribes hormone replacement therapy. This method, can for some time delay the onset of menopause, due to which, the childbearing function is prolonged. In such situations, the onset of an independent pregnancy is likely.
IVF procedure with low AMG
After receiving the results of tests according to which antimulylerov hormone in the blood is lowered, the decision about further actions should be taken only by a qualified doctor. Unfortunately, experts note that the most likely way to conceive a child in this case is to conduct IVF. Sometimes, it is necessary to use a donor egg.
If a woman categorically refuses to donate material, they can use artificial stimulation of the ovaries. But with a low AMG, it is more likely that this procedure will be ineffective. Such interference can lead to an even greater depletion of the ovarian reserve.
How to correctly pass the test
The indicator of this hormone, as a rule, does not change throughout the menstrual cycle. But to get the most correct and accurate results, the test is assigned to a woman on the 3rd or 5th day of the cycle.
To obtain the correct result, when venous blood is delivered to any laboratory study, it is necessary to adhere to certain rules. The test for AMG was no exception. In order to protect yourself from unnecessary disturbances due to incorrect results, the following recommendations should be observed before donating blood:
- a woman is strictly prohibited from smoking at least 1 hour before the procedure;
- a few days before the blood donation, you need to minimize physical activity. It is strictly forbidden to engage in sports, lift weights and tolerate strong physical strain;If possible,
- should avoid stressful situations. A few days before the study, it is not recommended to experience strong emotional outbursts, it is necessary to remain at rest;
- it is not necessary to take the test immediately after the transfer of an acute infection or some serious disease.
If at least one of the above factors has not been observed, this must be reported to your doctor. On his reasoning, it may be decided to postpone the test for another day. Since the analysis is paid, it will help to save money and save unnecessary worries if you receive incorrect data.
What to do after the test results are received
Typically, this study can be conducted from 2 to 7 days. Having received the results, do not try to decipher them yourself. Only the attending physician can do this correctly.
If you find abnormalities of AMG from normal, you do not need to panic, because this result is not the final sentence to infertility and the impossibility of an independent pregnancy.
Since the indicator only shows the correct functioning of the ovaries, and the performance of other organs, as well as the performance of other hormones, does not affect the level of AMH, at a high test score, it is necessary to search for the pathology of the ovaries .
If the test score is increased, the doctor prescribes a number of additional studies to exclude various neoplasms. First of all, it will be necessary to undergo ultrasound diagnosis.
In case of detection of tumors or polycystosis, prolonged therapy is prescribed. After its successful completion, when the factor triggering an increase in AMH is eliminated, re-submitting the analysis may result in a result that corresponds to the norm.
If the antimulylerov hormone is lowered, also do not despair. The real problem with the onset of pregnancy is possible only in the case when low AMG is observed with a simultaneous increase in the index of FSH( follicle stimulating hormone). That's why when the antimulylerov hormone in the blood is low, the doctor prescribes an additional study for FSH.
If the index of follicle stimulating hormone is normal, and pregnancy still does not occur, then it is necessary to continue searching for causes of infertility.
