The main active ingredient De-Nol is a bismuth subcitrate, colloidal. This material promotes the formation of the coating layer (film), which helps to protect the mucosa of the digestive tract and allowing quick scar damaged areas.
Indications De Nola
Analogs De-Nol used for the treatment of pathologies identical, which are as follows:
- ulcerative lesions nature arising on the mucosal surface of the stomach and intestines (including inflammation caused by Helicobacter pylori);
- gastritis, gastroduodenitis with an acute course, including the impact caused by Helicobacter pylori.
Let us look at the domestic counterparts De Nola, which include:
- Vikair;
- Novobismol;
- Escape.
1. Vikair
The active component of the analog De-Nol is a bismuth nitrate. Its formula also includes magnesium carbonate, sodium hydrogencarbonate, buckthorn (bark) and sup (rhizome).
Vikair is a complex substance that exhibits astringent and antacid effects. Bismuth nitrate promotes the formation of a layer protecting mucosal surface and relieves inflammation, and also assists speedy recovery. Derivatives of magnesium and sodium is reduced acidic component food juice, and calamus and buckthorn are mild laxative.
This analog De-Nol is produced in tablet form and its application scheme is as follows: the drug analog must be taken and 60 - 90 minutes prior to consumption of food, from 1 to 2 tablets three times a day. The medicine must be crushed and diluted with 1/4 cup boiling water. The duration of therapy is 30 - 60 days. Perhaps the appointment of a repeated course after the break.
Vikair produced pharmaceutical company "PFC Update" in Russia.
2. Novobismol
The main active component of the analog De-Nol is a bismuth tripotassium dicitratobismuthate, having antiulcer properties and gastroprotective. Forming a special film on the mucous membrane of the digestive tract, the drug protects damaged areas from the impact of a food juice, thereby allowing them to rapidly regenerate. This substitute De Nola contributes to the accumulation of a protein that stimulates cell growth and accelerate the regeneration of affected area, and inhibits the activity of pepsin and pepsinogen.
Medical tool analogue, taken orally, 30 minutes before a meal.
For patients who have reached 12 years of age, 1 tablet four times a day.
Children from 8 to 12 years of age should take 1 tablet twice a day.
Young patients from 4 to 8 years, the dosage is calculated on the basis of 8 mg per kilogram body weight. This amount should be divided into two stages.
The duration of the therapeutic course analog De-Nol is 4 to 8 weeks.
Novobismol produce pharmaceutical companies "Obolensky" and "pharm" in Russia.
3. escape
The structure of the escape part of the same active ingredient as in Novobismol - dicitratobismuthate tripotassium bismuth. The drug exhibits properties that are common to all products belonging to the group De Nol analogues. Escape to form a film on the mucous membranes of the digestive tract, which protects the damaged surface and allow it to recover as quickly as possible.
This analog De Nol should be used inside for 30 minutes before meals and drink boiled water. As with all medicines containing bismuth, Escape is not recommended at the same time with other medicines, and as dairy products, is difficult because the absorption process of the active substances from the digestive tract.
If your doctor has prescribed instead of De Nol drink Escape, the dosage for patients 12 years of age is 1 tablet four times a day, or two tablets twice during the day.
For children from 8 to 12 years old should consume one pill 2 times per day.
For children, from 4 to 8 years, the number is 8 mg drug per kg body weight per day.
The length of treatment 4 to 8 weeks.
The Russian equivalent of the De-Nol, produced pharmaceutical company "Otisifarm".
Import substitutes De Nol:
- Ulkavis;
- Venter;
- ventrisol;
- Vikalin.
4. Ulkavis and 5. ventrisol
One of the most unique in the cheap pharmacies are Ulkavis and ventrisol. Both the medical agents include its active component formula - bismuth derivative, which contributes to the protection film on the mucosal surface. Through the use of the drug is rapid regeneration of the ulcer and erosive damage.
Dosage of these two analogues De-Nol is exactly the same treatment regimen escape as described above.
Ulkavis released «KRKA» company in Slovenia.
Manufacturer ventrisol a pharmaceutical plant "CA" in Poland.
6. Venter
The main active ingredient of this analogue De-Nol - Sucralfate, composed of sucrose sulfate and aluminum hydroxide. By reacting with acids in the stomach, the component is converted into a viscous substance enveloping mucous and preventing damage to already injured areas. Because of the effect of sucralfate erosive and ulcerative lesions scarring and heal more quickly.
Analog De-Nol is produced in the form of granules, which are recommended to be taken 30 - 60 minutes before meals. A bag with the drug should be dissolved in half a cup of boiled water and drink.
For therapy usually assigned receiving one sachet of granules four times per day. An alternative would be the use of two sachets twice a day.
For children who have reached 4 years of age are allowed to use the drug at a dosage of 0.5 t to 1 g 4 times a day.
This analog De Nola is available pharmacological plants of the company «KRKA» in Slovenia.
7. Vikalin
Vikalin is an analogue of De Nol and quite often appointed to replace him.
The main components of this complex serve as means:
- subnitrate;
- magnesium karblnat;
- potassium hydrogencarbonate;
- buckthorn bark;
- rhizome;
- Kellin;
- rutin.
bismuth subnitrate (colloidal bismuth subcitrate analolgichno De-Nole) envelops an inner surface digestive organ protective layer and promotes removal of inflammatory processes and also rapid healing damage.
Magnesium carbonate and sodium hydrogencarbonate reduced acidic component and prevent food juice exposed cleaving enzymes.
Kellin and AIR are antispasmodics.
Buckthorn is a mild laxative.
Vikalin tablets are crushed and stirred with a quarter cup of boiling water. Medical device subject to ingestion after eating the food, and 1 - 2 pills three times a day.
The duration of treatment with this analogue De Nola is from four to eight weeks.
The appointment of a repeated course possible after the break and survey the attending physician.
8. Gaviscone
A wide range of drugs, united under the name Gaviscone, used for the treatment of the phenomenon and erosive lesions of the digestive tract, and can act as an analogue of De Nol.
The main active substance Gaviscone double action are sodium alginate, sodium hydrogencarbonate and calcium carbonate.
Calcium carbonate and sodium hydrogencarbonate help neutralize gastric acid index and help to quickly reduce the negative symptoms of ulcers (heartburn and digestive disturbances). Sodium alginate envelops the mucous of the gastrointestinal tract, thereby preventing injuries already affected zones.
Preparations from the series Gaviscone are analogues preparation De Nol and assigned to replace it in case of any adverse events or contraindications to main drug.
For patients below 12 years assigned from 10 to 20 mg (from 2 to 4 teaspoons) means, from 2 to 4 times a day. Before receiving the suspension should be carefully shaken.
The entire list of drugs produced Gaviscone pharmaceutical company "Rekkitt Benckiser Helsker" in the UK.
use Features
Before starting therapy in any of the analogues of De Nol, you must make sure that the patient has no contraindications to the drug. Otherwise, the treatment can give a negative result and cause serious consequences. Derivatives of bismuth in excess of a therapeutic dose may cause symptoms of renal failure requiring special treatment. That is why, if the analogue De Nola contains bismuth, contraindications for its use will be a violation of functional activity of the kidneys.
conclusion
Medication De-Nol used successfully for the treatment of ulcerative lesions of the digestive tract. Usually it means perfectly tolerated and cause adverse events are rare. One of the drawbacks of this drug is its high cost. Therefore, if the patient can not buy medicine or has a contraindication, then it is possible to replace De Nol the above analogs.
sources:
Vidal: https://www.vidal.ru/drugs/de-nol__6730
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 7696368a-c3a6-4fd8-b73c-69a9af455d51 & t =
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