Composition and pharmacological properties
The main and the only active ingredient in the composition of De-Nol is a bismuth subcitrate colloid. This substance has important properties that help it to be used successfully in the treatment of ulcers. Thanks to the film-forming effect De Nol protects the injured mucous membrane of the digestive tract from the aggressive action of acids and enzymes.
Causing increased local production of prostaglandins, the drug helps to reduce the acid number of food juice that can make it less aggressive and traumatic.
The drug has a bactericidal effect against Helicobacter pylor, which is the precipitating factor ulcers.
Why stools may be black
But back to the derivatives of bismuth, and try to find out why the feces black from De Nol. In fact, during therapy De nolom, feces can be painted not only in black color. May be present dark brown and green hues. This depends on the reaction body. Once in the stomach, of bismuth subcitrate is connected with other substances to form new, completely harmless components - bismuth sulfide. It was he and feces stains in black.
However, it is important to understand that not only De-Nol colors chair in black. The use of certain products, fruits and berries (e.g., mulberry) can also impart dark colors feces.
Admixture of blood, for the following diseases, create the effect of a black stool:
- growths in the rectum;
- ulcerative colitis, nonspecific type;
- proctitis;
- Crohn's disease;
- vascular pathology of the gastrointestinal tract;
- abnormal liver function are severe.
If the stool turns black without the use of drugs containing iron and bismuth, should consult a doctor for advice and undergo appropriate examination.
testimony
De-Nol is appointed for the treatment of the following diseases:
- erosive-ulcerous digestive tract damage;
- inflammation and damage to the gastric mucosa and intestine in the acute period (gastritis, gastroduodenitis);
- ulcerative diseases caused by exposure to H. pylori (Helicobacter pylori).
Contraindications
Before starting treatment De nolom should make sure that the patient is missing the following indications for the drug:
- sensitivity to bismuth and its derivatives, as well as substances included in the vehicle;
- disorders activity heavy nature of the liver;
- during pregnancy;
- lactation.
side effects
Despite the fact that De-Nol is well tolerated by patients, sometimes there may be side effects of symptoms that occur as follows:
- Color of feces when using the drug De-Nol is black or dark.
- there is a feeling of nausea or retching;
- develops constipation or frequent urge to defecate;
- allergic reactions such as itching reactions and typhus.
Most often, these symptoms are not dangerous and disappear after cessation of therapy. However, in any situation, they are worth to tell your doctor.
At a sufficiently large number of patients after De Nola black stool, which is a normal reaction and does not require any treatment. However, it is very important to find out - is the staining of feces bismuth sulfide or black blotches of blood. Since these effects can signal serious bleeding or other pathologies of the digestive system.
Overdose
Prolonged use of De-Nol in high dosage may serve to develop encephalopathies are associated with the accumulation of bismuth derivatives in the central nervous system.
When exceeding maximum therapeutic dosages may occur renal dysfunction, renal failure until (effects are reversible).
For the treatment it is necessary to wash out the stomach, hold a reception absorbents and laxatives. In severe impaired renal activity hemodialysis.
Dosage and treatment scheme
Reception De Nol should be administered orally, for 30 minutes before eating.
Patients from the age of 14 is assigned to 1 tablet 4 times a day. Alternative - 2 tablets twice a day.
Children from 8 to 4 years of age should consume 1 tablet De Nola twice during the day.
Toddlers from 4 to 8 years take medicine per 8 mg per 1 kg of body weight per day. This amount should be divided into two steps. The maximum daily dose of not more than 2 tablets.
The length of treatment should not exceed a period of 2 months. Most often, the course lasts 4 to 6 weeks.
For the treatment of pathologies occurring under the action of H. pylori, combined therapy is conducted in conjunction with omez, Tetritsiklinom and metronidazole.
use Features
Reception De Nol in excess of the maximum dosage can cause renal failure, until the development of renal failure, so it is very important to follow the treatment regimen prescribed by your doctor. Duration of therapy should not exceed 2 months. Purpose of the course can only be repeated after a certain period of time without the use of medication.
Black and green chair against drug de-nol - frequent display and does not require any action. However, we must distinguish, fecal staining black darkening of the stool and as a result of being hit by spotting.
Simultaneous treatment with dairy products or medical devices may reduce the effectiveness of the levers. De-Nol should be used separately from other medicines and foods, and the period between the reception should not be less than one hour.
The drug should not be used in the treatment of pregnant patients. If the medication administered during lactation, it is necessary to interrupt breast-feeding in the course of the treatment.
Before starting the use of medication, you must ensure that no patient contraindications. Otherwise, the treatment can cause severe complications.
conclusion
So, the answer to question patients why from De Nol ceases black feces, will be the next: Entering the stomach, colloidal bismuth subcitrate, specific reaction takes place in which the bismuth sulfide is formed. This substance is a black crystals, which were stained excrement patient black. In fact, it can change not only the color of the chair. During therapy De nolom may darken language that is absolutely normal. bismuth sulfide is completely harmless and does not cause any adverse effects, except for the color change.
Numerous reviews of physicians and patients, as well as data obtained after clinical trials of the drug proves it maximum effectiveness for the treatment of pathologies of the digestive system that are associated with ulcer and erosive lesions mucous.
sources:
Vidal: https://www.vidal.ru/drugs/de-nol__6730
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 7696368a-c3a6-4fd8-b73c-69a9af455d51 & t =
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