Information about vehicle
Pulmicort is a therapeutic component Budesonide. Budesonide inhalation acts at a cellular level. It normalizes the immune activity renders protivoekssudativnoe, antiallergic, anti-inflammatory effect.
The child can be inhaled Pulmicort form:
- suspension of 0.25 mg or 0.5 mg per ml each;
- powder Turbuhaler 100 ug or 200 ug 1 dose.
To dilute liquid nebulizer, a suspension is necessary to purchase a 0.9% solution of sodium chloride (saline). Symbicort - a type of inhaler that is convenient to use in the treatment of a child older than 6 years and adults. By turning the disc dispenser produces strictly set budesonide rate for one inhalation.
Indications funds
Pulmicort child to use in the suspension allowed to 6 months. Powder is used with 6 years. Assign children with asthma inhalation immediate and late types of COPD.
Other indications:
- bronchitis, laryngitis and other constrictive respiratory disease;
- coughing;
- respiratory failure on the background of cramps, swelling of the bronchioles;
- allergic laryngospasm.
On a note! Instead inhalation Pulmicort suspension can also be applied intranasally (nose) for seasonal allergic rhinitis.
Contraindications means
Neither children nor adults can not be used intranasally or Pulmicort inhalation at high sensitivity to budesonide. The drug is also contraindicated for people with active pulmonary tuberculosis, candida or other infections of the oral cavity and respiratory system.
drug interactions
In Pulmicort increasing effect in the complex therapy of itraconazole, clarithromycin, erythromycin. Estrogens or methandrostenolone enhance glucocorticoid action. In children, the combination of inhaled with taking ketoconazole possible intoxication. Cimetidine slightly reduces the clearance. Phenobarbital, rifampicin reduces the effectiveness of Pulmicort.
The advantage of inhalation means
Pulmicort inhalation of getting used to the action of budesonide in children do not cause. Asthma, COPD, complications of SARS permitted regularly prescribe repeated courses.
During inhalation Pulmicort agent is delivered directly to the site of disease, and only affects the mucous membranes of the respiratory tract. Therefore, minimal risk of side effects in children.
Pulmicort not penalized action comprehensively designated systemic drugs because budesonide inhalation does not react with their active substances. This allows you to apply the procedure with taking corticosteroids, bronchodilators, antibiotics and other groups of medicines, which speeds up the healing of the child.
Description of Action
During inhalation budesonide it penetrates the shell cell begins to suppress the production of prostacyclin, interleukins and other inflammatory mediators.
The child Pulmicort:
- reduces swelling of airway walls;
- It slows the production of sputum, mucus, fluid, allergic secret;
- Tracheobronchitis accelerating the expansion of the lumen;
- increases the resistance of the airway walls to physical stress;
- It reduces the sensitivity of the mucous membranes to allergens and other irritants.
Pulmicort causes the child systemic side effects when applied daily dosage of 400 .mu.g budesonide. After the procedure in 10% of cases there is hoarseness, nasal voice, another manifestation of dysphonia.
Pulmicort is also capable of:
- oropharyngeal candidiasis trigger;
- irritate the skin on the face at the contact mask;
- dry mucous membranes of the mouth, pharynx;
- cause contact dermatitis, sore throat, cough, paradoxical bronchospasm.
Pulmicort has a cumulative effect. When inhaled dosage overestimation provokes in the child's development of side effects of glucocorticoids. If the same amount of budesonide is not enough, treatment without result, it is possible worsening of the disease.
The need for manual adjustments
RF Ministry of Health in 2014. invited to complete preparations instruction with substance Budesonide. Inhalation with Pulmicort for children require incessant monitoring of their condition. Clinicians say that it causes nausea, difficulty swallowing, angioedema, urticaria, itching, change in taste. System Tools budesonide slow growth. Be wary of these drugs prescribed to adolescents, in patients with hypothyroidism, cirrhosis, glaucoma.
Price and analogues funds
July 2018 value Pulmicort suspension starts from Container 248 rubles №5 (five units 2 mL). Minimum price turbuhaler powder is 413 rubles.
The structural analogs include drugs Pulmicort code ATC R03BA02 for treating diseases with bronchospastic reaction. Babies allowed inhalations means Pulmaks, Novopulmon E Boudin Steri-Neb, Budekort aerosol budesonide (The native, Intel, Iziheyler).
Pulmicort child can replace drugs containing:
- beclomethasone - Altsedin, bekotid, maple;
- Mometasone - Asmaneks tvistheyler;
- fluticasone - Fliksotid, Flutikson;
- budesonide + formaterol - Symbicort Turbuhaler.
These means are suitable for inhalation of indications, a method of use. But each substitute Pulmicort does not match the age limit and there are features of the application. Medicine to a child shall be chosen by your doctor.
Features of treatment means
Pulmicort administered topically using the device for inhalation. Duration is from 3 days, sometimes lasts 2-8 weeks. During the procedure, the child must breathe correctly according to the instructions in the manual that the substance reached the bronchus.
After inhalation:
- the mouth is rinsed with water for the prevention of oropharyngeal candidiasis;
- using inhalers wash the mask to avoid irritation.
Pulmicort inhalation dosage calculated based on the number of system GCS actions pathology severity. If there are no other treatment regimen of corticosteroids, the child is prescribed an average daily high or age limit. For maintenance therapy using the minimum dose, the effectiveness of which is determined experimentally.
When the need for frequent application is necessary to monitor the growth of children of any age. In case of overdose doctors perform therapy regimen constitute a phased reduction in the number Pulmicort or analog means selected for inhalation.
Features of the application turbuhaler powder
The drug is used in pediatrics after 5 years. Inhalation children Pulmicort in Symbicort is held under the supervision of an adult family member. The bioavailability of budesonide is 38-40% of the powder has got to the mucous.
Typical daily dosages for the child and frequency of inhalation:
- 100 g 2-4 times / day at regular time interval;
- 100 mcg, 200 mcg, 300 mcg or 400 mcg once;
- 200 g 4 w / day every 4 h.
If you are using Pulmicort Turbuhaler should be controlled in the presence of powder. The medicine is over, if the red mark has reached the lower edge of the indicator window. In the bottle is only a drying agent.
Pulmicort inhalation powder:
- Open the cap turbuhaler.
- Keep the vial bottom vertically down when loading dose and during inhalation.
- Crank drive all the way counter-clockwise and back until you hear a click.
- The child must exhale away from the inhaler. Then he is given the mouthpiece in your mouth. It is necessary to slightly compress the teeth and lips to clasp.
- The child should breathe deeply and sharply mouth (air is sucked in through the parted lips) and hold your breath for 10 seconds.
- Pull the mouthpiece out of the mouth and allowed away from turbuhaler exhale.
- Tightly closed inhaler.
- Mouthpiece wipe the outside dry cloth. It is forbidden to wash any liquid.
If your doctor has prescribed more than one dose, repeat steps 2-6. The child does not feel on the mucous powder after inhalation. But it is necessary to rinse the mouth necessary, and to eat and drink nothing can be at least 30 minutes.
Features of the application suspension
In pediatric use child Pulmicort suspension in a dosage of 0.25 mg / 1 ml. Inhalation nebulizer make a child with six-month-old. When the complex course of the disease may be given medication with plenty of Budesonide in 1 ml.
Bioavailability budesonide estimated 15% of the used slurry. The daily rate and the multiplicity of procedures are selected based on its effectiveness in identifying the severity of the disease.
Often used in children's dosage Pulmicort suspension 0.25 mg / ml 1:
- 1-4 ml / day;
- 1-8 ml / day. (Maintenance therapy).
For the procedures used nebulizer container with a volume of 2 ml. airflow density should be 5-8 liters per minute. Ultrasonic devices for Pulmicort not suitable. Infants and children with impaired respiratory function need a special mask and the appropriate size.
Preparing for Pulmicort inhalation via nebulizer:
- Nonintensive container is rotated with the slurry for uniform distribution of budesonide.
- Give the containers upright and tear off one Nebula by turning on an axis.
- The suspension is extruded into a clean tank nebulizer in the amount prescribed by the child for one inhalation.
- When assigning doses up to 0.25 mg to add to a 1 mL suspension of 1 ml of saline solution, and stir.
Inhalation child do immediately after preparation of the solution, but it is possible to postpone the procedure for 15 minutes. If the nebula Pulmicort left, the container is put on the lower shelf of the refrigerator door opening upwardly. Undiluted suspension was used no later than 12 hours.
Instructions with Pulmicort inhalation:
- Before the procedure, the child is given to sit quietly, to keep him quiet, his breathing returned to normal.
- Firmly apply the mask to the face, include a nebulizer.
- The baby must breathe evenly and calmly. The air sucked by mouth, at a second 1-H delay breath after each inhalation
- The procedure is stopped when the liquid (about 15 minutes) disappears in the device reservoir.
After inhalation wash the child, rinse the mouth, clean parts of the nebulizer. The next 30 minutes upon completion of the procedure can not drink, eat.
conclusion
Pulmicort belongs to the non-systemic hormonal preparations. Inhalation risk of dysplasia or functions of internal organs and glands below 1%. But the treatment of the child should take place with a regular doctor's advice and supervision of his health, development.
sources:
Vidal: https://www.vidal.ru/drugs/pulmicort__1801
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 298bc255-c163-4775-8082-11b258936afc & t =
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