De-Nol - a drug used in gastroenterology for treating pathologies of the intestinal tube. De-Nol with gastroduodenitis often used. It allows you to restore the mucous membrane of the stomach and duodenum 12. The treatment gastroduodenitis cropped (cured) dyspeptic symptoms (heartburn, loose stools), decreases the intensity of pain. The medicine helps fight infection Helicobacter pylori.
Pharmacological properties, forms, indications and limitations to the appointment
De-Nol refers to an antiseptic and astringent intestinal of drugs. Means are effective component bismuth tripotassium dicitratobismuthate. The drug is available as a tablet form (120 mg).
Preparation healing ulcerative lesions and reduces propagation vital activity of the microorganism Helicobacter pylori. When the drug enters the acidic environment of the stomach, her settle oxychloride and bismuth citrate. Protein start to form connections, which are combined in the protective film. This helps to protect erosive and ulcerative lesions of the mucous from the effects of food and excess gastric secretion. When forming the protective film is formed mucus, which contributes to the stimulation of the healing of damaged areas. Against the background of the use of the drug decreases acidity, formation of pepsin and pepsinogen.
Constituent medicament hardly absorbed through the digestive tract wall. Excretion De-Nol is performed with the faeces. A small amount of drug that gets into the bloodstream, excreted in the urine.
Indications and limitations to the appointment of De-Nol
De-Nol has its indications and limitations for use. Their doctor must take into account in the appointment of the drug.
Indications for use of the drug:
- ulcerative lesion of digestive tract mucosa (+ presence of Helicobacter pylori bacteria);
- chronic gastritis and gastroduodenitis during acute (+ Helicobacter pylori infection);
- irritable bowel syndrome (diarrhea syndrome in the presence of unstable or chair);
- dyspeptic appearance, not caused by abnormalities of the digestive tract.
The drug is not used in patients with severe kidney disease, intolerance to the drug components during gestation, during breastfeeding. It should appoint De Nol children under 4 years of age.
gastroduodenita therapy in patients of different age
How many need to drink tablets? When gastroduodenite take De Nol should be strictly according to instructions. Adult and child over 12 years of age with gastroduodenitis (without concomitant infection Helicobacter pylori) shown by 1 tablet form cheryrehkratno per day. You need to take the drug for half an hour before meals. You can drink 2 tablet form twice per day. Tablets need to drink a small amount of liquid.
When gastroduodenitis in children 8-12 years of age is shown Take 1 tablet twice a day. Acceptance of drugs is carried out for half an hour before meals. Dosage De Nola from gastroduodenita a child 4-8 years of age is 8 mg per 1 kg of body weight per day. The daily dosage divided into 2 doses. Coursework therapy at any age is 1-2 months. During treatment, De nolom should not use other drugs, having in its composition, bismuth.
When combined gastroduodenita with Helicobacter pylori infection should drink De Nol in the same dosages. Lreat gastroduodenitis De nolom can together with antibacterial agents. When therapy is often used amoxicillin, furazolidone, Tetratseklin, Clarithromycin. The most frequent combination of antibacterial agents when gastroduodenitis caused by infection with Helicobacter pylori - is amoxicillin and furazolidone, metronidazole and Flemoksin.
conclusion
De-Nol is perfect for gastroduodenita therapy in adults and children from 4 years of age. Treatment should not last less than 1 month (the drug does not have time to give effect). Before using the drug should consult a doctor. The safety of medicines is sufficient, as almost not absorbed in the intestine. It is permissible to use with antibacterial drugs for the treatment gastroduodenitis associated with the bacterium Helicobacter pylori.
sources:
Vidal: https://www.vidal.ru/drugs/de-nol__6730
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 7696368a-c3a6-4fd8-b73c-69a9af455d51 & t =
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