Respiratory diseases, accompanied by cough with sputum hard, using special mucolytic agents that affect the rheological properties of sputum. Independently determine what is best Ambroxol or ACC, it is difficult. Prescribe the most appropriate treatment must physician, focusing on the patient's condition.
The principle of action of drugs
The main active component of ACC is acetylcysteine. The drug affects the mucus, reducing viscosity, facilitating the process of a discharge. Mucus remains unchanged. Acetylcysteine characterized pnevmoprotektornymi and antioxidant properties. It is able to neutralize free radicals, which act on the destructive cells.
Ambroxol active substance ambroxol is hydrochloride. Under its influence the viscosity of secretions, formed in the trachea and bronchi, is reduced. It stimulates the increase in the motor activity of the epithelial cilia, thereby accelerating the process of discharge of phlegm formed.
But the principle effect of these drugs on the body varies. ACC mucus contributes to the destruction of molecules, it destroys the link between mucopolysaccharides, which are in the sputum. This helps to reduce its viscosity and expedite the process of withdrawal from the bronchi. When antibiotic therapy is necessary to make a break between the consumption of ACC, and many antibiotics, as these agents weaken the effect of each other.
Ambroxol acts on the glands, which are located in the airway mucosal surfaces. It helps to increase the liquid portion of sputum, its amount is increased, but it becomes so viscous. Under the influence of Ambroxol in the bronchial secretions increased concentration of antibiotics produced on the basis of cefuroxime, erythromycin, amoxicillin.
Therefore, instead of starting their own ACC drink Ambroksol doctors do not recommend.
Indications for use
Prescribe drugs, pick up the dosage, duration of therapy should be installed only by a doctor. Prescribe a cough Ambroxol take ACC or in diseases in which there is a viscous mucus in the airways.
These mucolytic drugs prescribed for such diseases:
- bronchitis (acute and chronic forms);
- bronchial asthma;
- pneumonia;
- COPD;
- bronchiectasis.
Ambroxol may also recommend the development of respiratory distress syndrome in newborn babies, including premature.
ACC when coughing administered to patients who have:
- obstructive bronchitis;
- lung abscess;
- cystic fibrosis;
- bronchiolitis;
- laryngotracheitis.
ACC good effect on patients with otitis media and sinusitis.
Due to the different operating principle of the list of indications for use of ACC and Ambroxol slightly different. Therefore, decide which tool is best suited, should the treating physician. Where indicated, physicians recommend, along with taking the drug ambroxol ACC.
used combinations
According to established standards of treatment in some diseases showing several combinations of mucolytic drugs. This increases the effectiveness of therapy. Comprehensive treatment is given mainly for respiratory diseases in difficult cases.
Patients often wonder Ambroxol and ACC can we take together. Independently start combining these drugs can not. With the combination of these means physician must paint recommended regimen. The standard duration of combination therapy is 1 week.
These drugs reduce the viscosity of sputum, mucus accelerate discharge of process by increasing the activity of the work of the epithelial cilia. Compatibility Ambroxol and ACC confirmed in the course of numerous studies.
On the admissibility of the use of such combinations is demonstrated by the fact that there are drugs in the sale, which is used in the production of acetylcysteine and ambroxol hydrochloride at a time. These medicines include:
- Pulmobriz;
- Respiks;
- Helpeks.
Assign them not only in acute and chronic forms of diseases of the respiratory system. Used drugs for the prevention of complications after lung surgery, before and after bronchoscopy. Also, these tools help to prevent the deterioration of the patients who installed traheostroma.
possible substitutes
In diseases characterized by the appearance of cough with sputum difficult, the doctor may prescribe mucolytics. Used not only Abraksol and ACC. The list of popular cough medicines include drugs manufactured from bromhexine hydrochloride or karbotsisteina.
Analogue ACC when coughing is Fluimucil preparation. Replace it can also means:
- acetal;
- Atsetin;
- Kofatsin
- Evkabal.
In the manufacture of these drugs is used acetylcysteine.
Instead Ambroxol may appoint:
- Lasolvan;
- Flavamed;
- ambrobene;
- Bronhoksol;
- Ambrogeksal.
In the manufacture of these tools used ambroxol hydrochloride. Ambroxol list of substitutes is large enough. The Index of the book dedicated to the treatment of respiratory diseases, it is possible to find a complete list of diseases in which the use of different groups of mucolytics.
the prescribed dosage
Knowing the principle of action of each drug on the human body, you can decide which tool is better. Patients suffering from non-productive cough, often prescribed ACC. Most people respond well to this therapy.
Adults with respiratory diseases, accompanied by cough, appoint 400-600 mg of acetylcysteine per day. Said amount of drug necessary to drink in 1-3 doses after meals. Enhance the effectiveness of ACC action possible if, in addition to start drinking plenty of water.
If a patient has impaired secretion of bronchial mucus of the respiratory tract is moving slightly, the doctor may prescribe Ambroxol. Adults and children over 12 years prescribed medication in tablet form. Within 2-3 days of starting treatment you should drink 1 tablet of 30 mg three times a day. On the fourth day is recommended to drink 2 tablets per day.
To enhance the therapeutic effect of a doctor may prescribe Ambroxol drink 2 tablets twice a day. The standard duration of therapy is 4-5 days.
Combination therapy ACC and ambroxol are advantageously administered to adults and children over 12 years. The physician can prescribe the treatment in accordance with which to drink 200 mg NAC and Ambroxol 30 mg per day.
sources:
Vidal: https://www.vidal.ru/drugs/acc__3281
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 44e01d87-2e4b-40d0-9c82-0052960e36b3 & t =
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