To reduce the risk of blood clots in the blood vessels, reducing the likelihood of heart attacks, ischemic strokes designate specific antiplatelet drugs. Choose what is best Plagril Cardiomagnyl or should the physician, focusing on the health of the patient and diagnosis.
Mechanism of action
Plagril tablets are based on gdirosulfata clopidogrel. This tool is an analog of the French drug Plavix. When producing cardiomagnyl used acetylsalicylic acid (aspirin) and magnesium hydroxide.
The difference between the drugs is a special influence on blood clotting. When ingested Plagril has antiagregatine and vasodilatig action. The active component is selectively decreases the intensity of binding and platelet ADP receptors. After receiving the 400 mg drug aggregation process is inhibited by 40%. After 4-7 days of application Plagrila 50-100 mg aggregation is inhibited by 60%.
Cardiomagnil inhibits the synthesis of prostaglandins and thromboxane. The maximum blood concentration of aspirin has been observed after 2 hours.
testimony
To compare with Plagril Kardiomagnilom, you need to understand in what circumstances prescribe these medications.
Cardiomagnil used for the prevention of blood clots in the vessels. Using prevent tablets manages degradation in patients suffering from:
- diabetes;
- hypertension;
- obesity (body mass index 30);
- hypercholesterolemia.
When a bad family history (in the case of heart attacks among close relatives under the age of 55 years) is also necessary to apply Cardiomagnyl or analogs.
In accordance with an instruction Plagril administered to patients who have:
- history of myocardial infarction (treatment must begin within 35 days after the occurrence);
- ischemic stroke (the recommended starting date of treatment - from 7 days to 6 months from the date of occurrence);
- peripheral arterial disease;
- acute coronary syndrome.
Plagrilom therapy can prevent the occurrence of atherothrombotic events in patients at risk.
Features of therapy
Treatment strategy for each patient is chosen individually, depending on the diagnosis. In acute coronary syndrome with Plagrilom take Cardiomagnyl necessary. Combination therapy is prescribed for the long term. Reviews of patients with acute myocardial confirm that cardiologists often advised to drink drugs for several months. If necessary, treatment prolongs, deadlines physicians do not establish.
at the same time it is not necessary to drink Kardiomagnilom Plagril drug for thrombosis prophylaxis. If no history burdened monotherapy aspirinosoderzhaschim means will suffice. Cardiomagnyl during maintenance therapy is administered in a dosage of 75 + 15.2 mg per single dose. Tablets 1 are drunk once a day.
Plagril drink 1 tablet of 75 mg daily. When the need for combined treatment is prescribed 75 mg of clopidogrel and 75-325 mg of acetylsalicylic acid.
Independently replaced Plagril Kadiomagnilom doctors advise. After all, the principle of action of drugs is different, they have different indications for use, contraindications. Some patients want to replace Plagril due to the high price of the drug: 30 tablets cost 317 rubles. A similar number of cardiomagnyl will cost 133 rubles. If necessary, pick up a cheap substitute better to consult a doctor.
sources:
Vidal: https://www.vidal.ru/drugs/cardiomagnyl__35571
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = f69f6730-3d62-45e5-91ac-bc4e0c3b667f & t =
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