Lytic mixture - why is it necessary?
Hyperthermia is a protective state that helps in the fight against bacterial and viral agents. Heat to accelerate chemical reactions, reduce microbial growth rate. Temperature causes faster coming leukocytes and macrophages to the site of infection.
It is considered to be relatively safe hyperthermia up to 38.5 ° C. At higher temperatures the contrary begin to slow down the enzymatic reactions, phagocytosis and other processes. marrow cells at a temperature above 39,5 begin to die. This is very bad for the adult and the child's body.
Fever has 2 versions:
- pink;
- white.
When the pink fever child or adult is red, the skin on the entire surface of the hot. This fever is not dangerous to 38,5 ° C. It carries a protective response. White fever manifested pallor of the skin, cold hands, feet. Although cold extremities of patient temperature may rise to 40 ° C. Cold hands and feet, blanching of the skin is due to vasoconstriction. Much blood circulation in the brain and in the periphery.
hypothermic mixture - is the use of multiple medications for quick relief of fever. It can be carried out using 2 or 3 drugs. Lytic mixture made from tablets or injecting drug forms. Hypothermic mixture indicated if the patient has a temperature above 38,5 ° C, not cropped antipyretic drugs white fever, untreatable.
The mixture usually contains a non-steroidal component, antispasmodic, antihistaminic component. Non-steroidal component can be represented by analgin or paracetamol. Antispasmodics papaverine acts or No-Spa. Antiallergic drugs may be Suprastin, Pipolphenum or Tavegil. Suprastin anti-inflammatory effect, enhances the effect of antipyretic and spasmolytic component. Suprastin has anti-allergic effects, thus reducing the likelihood of allergies by using other means.
The most popular combination is to reduce the temperature Analgin, diphenhydramine, papaverine. They are used as injectable or tablet form for adults. Children Analgin, diphenhydramine, papaverine are sometimes used by doctors ambulance. In the appointment of Analgin in children is possible agranulocytosis, which can lead to the death of a child. Therefore, try not to use Analgin in pediatrics. The medicine should not be taken for children under 10 years of age.
Hypothermic active mixture is used in hyperthermia white type. The drug complex necessarily has an antispasmodic drug. It promotes vasodilatation that improves the condition of the patient.
When hyperthermia is often prescribed child Suprastin, Paracetamol and Nospanum. This combination is relatively safe. Paracetamol is permitted from 1 month of age. Suprastin used in children from 1 month. No-Spa as part of lytic cocktail assigned to 1-3 years. It is better to try to avoid hypothermic mixture in children up to 3 years.
Suprastin safer than papaverine. In pediatrics it may be used as a syrup. Paracetamol is also manufactured in syrup and tablet form. It is well relieves hyperthermia in conjunction with suprastin But-Shpoy.
Terms of Use hypothermic mixture in adults
Hypothermic mixture can be made from tablets and injectable forms of medicines. When hyperthermia white blend must contain antispasmodic. Adults can make the lytic mixture of Analgin, diphenhydramine, shpy. For the treatment need to take 1 tablet form Analgin, 1 tablet form diphenhydramine, 1-2 tablets shpy. In adult practice it is allowed to use Paracetamol, No-Spa and Suprastin temperature. This combination is not less effective.
The dosage of paracetamol shpy and suprastin:
- 1 tablet form Suprastinum;
- 1 paracetamol tablet;
- 1-2 tablet form shpy.
If there is no paracetamol or Analgin, Ibuprofen may be used with suprastin But-Shpoy. Suprastin can replace similar products: Zyrtec or Tavegil (drug allergy). Zirtek refers to second (more modern) generation antiallergic agents, unlike Suprastinum. Suprastin Tavegil are first-generation drugs. Multiplicity of hypothermic mixture is 1 every 6-7 hours. Often do not drink it. If the hyperthermia is not stopped, it is necessary to call an ambulance.
If there is vomiting on the background of hyperthermia can be a mixture of lytic intramuscularly. Most use the following combination of drugs Analgin 50% - 2 ml papaverine or No-Spa 2% - 2 ml, 1% Diphenhydramine - 1 ml. The effect of the treatment is 20-30 minutes after injection.
hyperthermia therapy in children
Children often used for the relief of hyperthermia Paracetamol Nospanum, Suprastin. These drugs are considered to be the safest. Lytic mixture of paracetamol, but-Shpoy, suprastin better to do for children from 3 years. Previously, the mixture should not be done. If a baby under 3 years of age does not decrease the temperature, it is best to call an ambulance. Safer combination at ordinary temperature (not white) will Suprastin with paracetamol.
Dosages of paracetamol and suprastin:
Paracetamol |
suprastin |
|
|
The effect of the treatment will come in fifteen minutes. Next paracetamol suprastin and should not be used 6-7 hours.
Paracetamol may be used by temperature and No-spa. This combination of good help when white hyperthermia. Paracetamol reduces the temperature. No-Spa will reduce vasospasm.
Paracetamol |
Dosages shpy children: |
|
|
White fever docked after 20-30 minutes after administration of paracetamol with antispasmodics. If the baby had complications (allergies, stomach bleeding), you should call an ambulance.
Often used Nospanum temperature. It is taken in the same dosage as for the lytic cocktail. It is effective at a fever white type. According to the instructions, but no-spa is permitted for use only in children older than 6 years of age, therefore, prior to its use in patients under 6 years of age need to see a doctor.
To prepare the mixture of lytic child should be crushed tablet form in a small cup or saucer. After grinding is supposed to be a very fine powder. The powder is poured water. Give the child to drink liquid. Medication be sure to drink a sweet juice or tea. the taste of the solution is very bitter, so children do not drink it. on the background temperature is often a child's drugs cause a gag reflex.
If the child vomits on the bitterness of the drug, it is better to replace the most of children's medication form. Paracetamol, Suprastin produced in the form of syrup. For hypothermic mixture Paracetamol and Suprastin will need to give the child the recommended dosage of a single age-appropriate. Nospanum have to give a tablet.
Suprastin may be replaced by Zyrtec or loratadine. The mixture was also prepared with Nurofenom. They replace Paracetamol. The combination of Nurofen, shpy Zirteka and very effective. From this treatment adverse events would be much less. Nurofen for children and Zyrtec is used as a syrup. Nospanum in tablet form. No-Spa is very bitter, so it is better to drink a juice or sweet tea. Tablet shpy can also be mixed with the syrup Nurofen and drops Zirteka.
If the patient is vomiting on oral forms of drugs, it is necessary to make hypothermic mixture intramuscularly. Paracetamol for injecting does not apply. Increasingly use Analgin.
Hypothermic injection mixture in pediatric practice:
medicine |
Toddlers up to a year |
Children after 1 year (n-number of complete years) |
analgene |
10 mg per 1 kg baby weight |
0.1 mL * n |
Diphenhydramine |
0.1 ml |
|
Papaverine |
0.1 ml |
This was made only with the ineffectiveness of simple antipyretics (Paracetamol, Nurofen), and if the child has severe vomiting. Hypothermic mixture is shown to use if you do not help spark paracetamol and Nurofen.
conclusion
Lytic mixture of paracetamol, suprastin, No-Spa is an extreme measure for the relief of hyperthermia. To prevent its use should promptly treat respiratory diseases and other pathologies that can cause fever. It is right to take antipyretic drugs.
In the presence of vomiting is better to try hypothermic funds in the form of suppositories. When the candles form does not work, you can do the lytic mixture. For children a suitable combination to rapidly reduce the temperature is paracetamol or Nurofen, Suprastin, No-Spa.
In adults not use Analgin, shpy, suprastin. The price of drugs is not high. Reviews on the use of a mixture of positive hypothermic doctors and patients. Therapy can be carried out only by the doctor's recommendations.
sources:
Vidal: https://www.vidal.ru/drugs/suprastin__789
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = a90310f8-1e55-491e-8e09-4a0ff15be728 & t =
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