The composition and dosage form
Augmentin active substances protrudes amoxicillin and clavulanic acid. Released in the form of tablets of 0.5 g and 0.125 g of antibiotic acid or slurry of 0.4 g and 5.7 mg amoxycillin acid. The slurry prepared from the powder - white and odor.
Vial sold amount of powder for the preparation of 70 ml of suspension. Tablets of 14 pieces per pack.
medicinal properties
Augmentin comprises semisynthetic origin of antibiotic that inhibits the synthesis of protein molecules necessary for the construction of cell walls of pathogenic microorganisms. This leads to the fact that the cell wall is weakened, and they die.
The acid in the drug composition in chemical structure similar to penicillin. It prevents bacteria inactivating effect on amoxicillin. In case of receiving only the clavulanic acid is not mentioned pharmacological activity as an antibacterial agent.
Antibacterial activity is exhibited against staphylococci, streptococci, enterococci, gram-positive and gram-negative anaerobic bacteria.
The drug is absorbed after oral administration quickly deduced the urinary system in an inactive form. The main elimination organ - a kidney. Patients with kidney and / or liver observed slow metabolism and excretion of the drug, as required reception with caution.
The decision as to whether the drug during pregnancy should be made solely by the doctor! Do not self-medicate!
Indications for
The use of Augmentin is indicated for these pathologies provoked by sensitive pathogens:
- acute bacterial sinusitis;
- inflammation of the middle ear in the acute phase;
- exacerbation of chronic forms of bronchitis;
- pneumonia;
- inflammation of the bladder, pyelonephritis.
Appointed by infection of the skin and soft tissue abscesses. Take Augmentin is recommended as part of an integrated treatment of infections of joints and bones.
Contraindications
Drink Augmentin strictly contraindicated in the presence of allergic reactions to its components in history. If there are cases of hepatic dysfunction in patients receiving antibiotics, can not take the drug.
Safety during pregnancy
Manufacturer investigated the effect of Augmentin during pregnancy on the development of the fetus and the mother state. Animal studies have shown that the drug has no toxic or teratogenic effects on the fetus. The use Augmentin during pregnancy may be associated with the risk of enterocolitis in infants.
During pregnancy in 1 trimester to drink Augmentin is contraindicated. This applies to all drugs, including antibiotics and others. Augmentin decision to admit a woman in the first trimester of pregnancy can only be made by the attending physician - in this case, the medication taken only under his supervision in a hospital.
When medication is prescribed during pregnancy
Before drinking during pregnancy Augmentin, you need to go study in the bacteriological laboratory - that the results of bacteriological seeding indicate the absence or presence of infection, as well as its sensitivity to the components of Augmentin.
In pregnancy, the decision to appoint Augmentin can be taken doctor if confirmed infectious aetiology of these diseases:
- inflammation of the respiratory system;
- the defeat of the nasopharynx and oropharynx;
- erosion and inflammation of the mucous membranes and skin;
- the defeat of the urinary system;
- inflammation of the pelvic organs;
- blood poisoning;
- exacerbation of sinusitis.
In order to prevent the drug is not appointed, as it can provoke resistance in the future.
Talking about specific diseases, Augmentin helps to cope with a sore throat, bronchitis, pharyngitis during pregnancy. Since during pregnancy may worsen chronic diseases, it is recommended for Augmentin cystitis, sinusitis, pyelonephritis, aggravated by increased stress on reproduction system.
How to take the tablets
Specific dosage depends on the severity of the disease, gestational age and duration of treatment. The physician determines in what dosage during pregnancy to take Augmentin, depending on bacteriological culture results, the number of detected infection, and its sensitivity to the drug.
The tablet form is administered in dosages of:
- 1 tablet three times a day after meals for mild to moderate disease;
- 2 tablets with the same multiplicity of reception in severe pathology flow.
In one method can be no longer eating 1.2 g amoxicillin.
Receiving and preparing a suspension of
Augmentin applied in slurry form must inwardly during meals to prevent possible intolerance on the part of the gastrointestinal tract.
Preparation of the suspension:
- check the integrity of the bottle cap of the powder;
- turn the bottle and shake to loosen the contents;
- open the lid, pour boiled carbonated water - level it should coincide with the red stripe on the vial;
- close the lid, shake the vial until a suspension with homogeneous consistency;
- open the lid and pour more water to the level of the black stripes, shake again;
- leave to stand for 5 minutes to complete dissolution.
Before each meal should be carefully shaken suspension. Pregnant drink Augmentin in slurry form shown three times a day until the disappearance of symptoms of the disease and for the supervision of a physician. In case of severe course of the disease it is recommended to switch to tablet form.
During lactation
Both existing Augmentin component can penetrate into breast milk, but no information on the impact of the state of the baby there. Presumably, the infant may develop diarrhea, mycotic lesions of the mucous membranes.
If necessary, use Augmentin during breastfeeding have to consider the transfer of the child on artificial feeding, or the selection of other drugs for the mother.
Adverse reactions
Despite the high safety profile of the drug during pregnancy the body can be more sensitive to its action and respond undesirable effects.
While taking Augmentin during pregnancy can develop such adverse reactions:
- mycotic lesions of the mucous membranes and skin;
- dizziness, indigestion;
- elevated liver transaminases in laboratory determination;
- skin rashes.
Last symptom indicates the presence of an allergic reaction - a direct indication for the immediate lifting of the drug.
Least likely to have headaches, dizziness, itching, rash, jaundice. With the same frequency: diarrhea, vomiting, nausea, cramps and hyperactivity extremities, forms reversible leukopenia, thrombocytopenia, agranulocytosis, anemia.
Detect any adverse reactions, especially during pregnancy, stop taking Augmentin and seek medical advice. He will lower the dosage or select another drug.
When the reception is dangerous for pregnant Augmentin
During pregnancy should not take Augmentin if the child runs hard gestation and the pregnancy is threatened by natural interruption. When the mother is weakened during pregnancy, taking Augmentin can cause fatigue and a general deterioration of health.
If necessary, eliminate infectious pathologies in severe portable pregnancy in the first place, recommended immunostimulatory and immunomodulatory agents are allowed during pregnancy for annotations.
Should stop taking Augmentin during pregnancy unless it is accompanied by:
- the emergence of adverse reactions;
- deterioration of health;
- detection of fetal abnormalities during routine monitoring of its state;
- the lack of therapeutic effect.
In either case, it is necessary to know your doctor and do not take Augmentin until the end of pregnancy. The physician will select other drugs and identify the cause intolerance or lack of efficacy.
sources:
Vidal: https://www.vidal.ru/drugs/augmentin__96
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 181e9388-c7af-4899-a60b-cbf46ad9e251 & t =
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