Antimicrobial Drugs For Systemic Use

Furadonin cystitis. Reviews of doctors, instructions for use, analogs and substitutes

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furadonin often used in cystitis and other diseases of the urinary system. Reviews of preparation controversial, as it may provoke negative reactions if used improperly. However, the drug effectiveness is proven by laboratory testing and treatment experience of many patients.

The content of the article:

  • 1 Release form and composition of the drug furadonin
  • 2 pharmacological properties
  • 3 Pharmacodynamics and Pharmacokinetics
  • 4 Indications
  • 5 Contraindications
  • 6 At what age can use the drug
  • 7 Instructions for use, the dosage of the drug
  • 8 The course of treatment of cystitis furadonin
  • 9 Side effects
  • 10 Overdose
  • 11 special instructions
  • 12 drug interactions
  • 13 analogs
  • 14 Terms, conditions of sale and storage
  • 15 Price in drugstores of Moscow, St. Petersburg, regions
  • 16 Reviews of the effectiveness of
  • 17 Videos about furadonin

Release form and composition of the drug furadonin

Drug means comprises composed nitrofurantoin substance as an active component. Ingredient belongs to the group of antimicrobial components, it has a pronounced therapeutic properties and helps to quickly eliminate the symptoms of many diseases.

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In addition, the tool provides additional ingredients:

  • Magnesium stearate.
  • Calcium stearate.
  • Silica.
  • Potato starch.

Additional ingredients act as a preservative, help give the agent the right shape and preserve the properties of the main component.Furadonin cystitis. Instructions for use, price, reviews, analogues

The drug is available in tablet form. Each tablet contains 50 or 100 mg of active ingredient. Means is packaged in blisters, which are placed in cartons. Each of them may be 12, 20, 30, 40 or 50 pieces. For blisters instruction manual.

Means can also be purchased in slurry form for oral administration, as well as the powder from which the solution is prepared for oral use. Powder packets are also in the carton, they provided instructions. The suspension is placed in a vial, which is in a cardboard box.

pharmacological properties

Furadonin cystitis (a means of feedback is useful to study before treatment) is used quite often, because it has several pharmacological properties.

The active component is an antimicrobial agent, which belongs to the group of nitrofurans. The substance has not only a bacteriostatic action, i.e. slows bacterial growth and development, but also has antibacterial properties, which allows to destroy pathogens.

In addition, the drug prevents complications even at an advanced stage of cystitis and other urinary tract abnormalities. Additionally means prevents redistribution of germs on the mucous membrane of the bladder, urethra.

It should be noted that the pharmaceutical substance effectively fights with staphylococci, streptococci and E. coli. It pretty quickly destroy shigella. All these organisms are often provoke an inflammatory disease of the urinary tract.

Pharmacodynamics and Pharmacokinetics

Pharmacodynamics means starts after its penetration into the human body. The active ingredient rapidly concentrated in the affected area, namely in the urine of the patient that It allows him to work on micro-organisms, which are located on the walls of the body and mucous urethra.

Nitrofurantoin almost immediately stops the growth and development of microbes, so the patient feels much better.Furadonin cystitis. Instructions for use, price, reviews, analogues

The number of bacteria is not increased, while remaining in the body die rapidly as a component it has a bactericidal effect. With this slows the progression of the disease, inflammation does not extend over large areas of the inner walls of the bladder.

Destruction of microbes makes it possible to start the process of rebuilding the walls of the bladder and urethra. Shallow ulcers and erosion disappear eliminated symptoms of inflammation. The patient feels much better after a few days of treatment means.

The pharmacokinetics of the drug was studied by experts under laboratory conditions. It is noted that the active drug component spreads rapidly in the body, enters the systemic circulation, and breast milk. In addition, nitrofurantoin able to overcome the placental barrier.

When used in said medication dosage its concentration in blood is small. When above the threshold indicated elevated levels of nitrofurantoin in the blood.

Absorption of the drug begins in the digestive tract. Its bioavailability is about 50%. When the use of food, this percentage increases. This effect is not typical to many antimicrobial agents, which makes furadonin effective.

The metabolism of the active ingredient takes place in the patient's liver, and muscle tissue. The substance is almost does not accumulate in tissues and organs, excreted by the kidneys in the urine. About 50% of the active component is evacuated from the body unchanged. In patients with severe renal failure marked slowdown in removing the drug.

If the patient suffers from advanced forms of kidney failure, the excretion of active ingredient slowed down for a few hours. However, in most cases, cleansing the blood and all tissues in less than 24 hours.

Indications

Furadonin used not only in cystitis varying severity.

Testimonials prove its efficacy in other diseases:

  • Pyelonephritis the initial and advanced stages.
  • Urethritis severe form characterized by severe symptoms.
  • Pyelitis different shapes and severity.
  • Prevention of infection of the bladder and urethra during cystoscopy.
    Furadonin cystitis. Instructions for use, price, reviews, analogues
    Cystitis (bladder infection) is most often diagnosed in women

In some cases, the drug is used during urological surgery. A catheter as bladder catheter insertion for a long period. In each case, the decision to appoint a doctor takes medication.

Contraindications

The main contraindications to the use of drugs is considered intolerant of any of the components of the means or inclination to allergic manifestations. It is not necessary to use the medication at advanced stage of renal failure, as its components may adversely affect the patient's condition due to delayed elimination.

Furadonin contraindicated with any degree of hepatic cirrhosis. This is due to the fact that the active substance is processed in the liver, and its defeat would not allow to carry out the process and obtain a therapeutic effect. When porphyria tool is also not assigned, especially in the acute phase. It is contraindicated in any form of hepatitis and the severity.

The drug is not used in the treatment of pregnant and lactating women and children under the age of 4 weeks. elderly patients caution should be exercised, as increases the probability of complications associated with age-related changes in the liver and kidneys.

Another contraindication is considered chronic heart failure to progressive and advanced stage, when the patient undergoes regular hospital treatment.

At what age can use the drug

Furadonin cystitis (ratings patients about a predominantly positive), and other pathologies of the urinary system are allowed to use small older than 4 weeks. In this case, the child is prescribed a suspension.

Powder and tablets can be administered to patients over 12 years old. First appointed rarely, tableted means most often used.

Instructions for use, the dosage of the drug

A medicine used after a preliminary diagnostic study and clarify the causes of the disease. Dosage is also determined by individually considering the severity of symptoms and concomitant manifestations.Furadonin cystitis. Instructions for use, price, reviews, analogues

The daily dosage for an adult is 3-4 tablets depending on the stage of the disease. Take the entire dose at once is not necessary, it is necessary to divide it into 3-4 hours during the day. The gaps between the consumption should be equal. Permission is granted to use the medicine before or after a meal, the therapeutic effect of this is not weakened.

In severe disease maximum daily dose is increased to 6 tablets. It is necessary to use 2-3 times with equal time intervals between doses. Specialists point out patients that the tablets should drink plenty of fluids and should not be chewed. The last recommendation is associated with a bitter taste of the medicine.

Sometimes medication is used to prevent recurrence of chronic diseases of the urinary system. Thus, the daily dosage is 2 mg per kilogram of body weight, i.e. 1 tablet (100 mg) was calculated per 50 kg. The calculation carried out by experts, it can be rough, but it has to be agreed.

Children are usually administered in suspension of 5 mg per 1 kg a day. This dosage is divided into 3 admission and give your child at regular intervals. Duration of the course for an adult and a child is determined individually and ranges from 5-10 days, depending on the severity of the condition.

The course of treatment of cystitis furadonin

Furadonin cystitis (reviews of the preparation you need to learn before you start the application) shall be appointed by the standard therapeutic scheme. The day the patient receives from 3 to 6 tablets depending on the states of neglect. Duration of treatment depends largely on the patient's body and the presence of concomitant disorders by the kidney, urethra.

Typically, only 10 days of treatment to eliminate the acute symptoms and a significant improvement in the patient's condition. It is important to remember that in the period of treatment should be preferred protein foods, drink less juice and stewed fruit.

If necessary, the course is extended to 14 days, but only with the permission of the expert. Separate dosage increase and prolongation of therapy is prohibited.

Side effects

Side effects when using furadonin may occur in compliance with the instructions and its violation.

The most frequent complications are:

  • Shortness of breath and cough, infringement of inhalation and exhalation process. Very often such symptoms are observed in patients with chronic disorders of the respiratory system.Furadonin cystitis. Instructions for use, price, reviews, analogues
  • Disorders of the digestive system in the form of vomiting, loose stools, pain in the stomach, reducing appetite. In severe cases, anorexia symptoms appear.
  • Headache, weakness, dizziness. Many patients experiencing drowsiness and impaired concentration, memory impairment.
  • Reduction in the number of blood platelets, leukocytes and erythrocytes, signs of anemia.
  • Pain in joints and muscles, fever, until the development of fever.

An allergic reaction to the agent is manifested not so often, but accompanied by a rash, irritation and peeling of the skin on the torso, feet or hands. In each case, a set of side reactions may differ.

Overdose

When you receive a high-dose, means for several days, there are signs of overdose. Typically, the patient feels nausea, repeated vomiting occurs, which is not associated with food intake and does not facilitate the patient's condition.

In addition, the possible aggravation of the symptoms of allergy. Itchy skin is enhanced, the patient noted an increase in number of lesions, the appearance of vesicles filled with a transparent liquid. Combing they are damaged, that only aggravates the condition.

When adverse reactions, experts recommend, stop taking money and ask for help. Within a few hours of symptoms should be less pronounced, but doctors still recommend gastric lavage and appropriate treatment to eliminate other symptoms.

special instructions

It is not recommended during treatment furadonin drink acidic juices, drinks or fruit. This is due to the fact that the sudden change in the acid-base balance in the urine of the active ingredient of the preparation is not able to fully destroy microorganisms that provoke inflammation.

Furadonin cystitis. Instructions for use, price, reviews, analogues
Furadonin not building combined with fluoroquinolones in the treatment of cystitis

In patients who suffer from hypovitaminosis or anemia, the risk of developing neuropathy increases the treatment agent. When inflammation perinephric space or prostate medicament is not used, because no therapeutic action.

Patients with chronic diseases of the digestive system better to use tablets with milk or food to reduce the chance of complications. Such a method is considered more effective, as a meal enhances the action of the active medicament component.

drug interactions

Furadonin cystitis (reviews of the facility are positive and negative, depending on the individual patient), and other pathologies of the urinary system is not used in combination with other medicines from the group nitrofurans.

It can not be combined with the passage of chemotherapy, as well as taking strong antibiotics from the group of fluoroquinolones. Drugs that block tubular secretion in the kidney, reduce the effectiveness of the drug, so you should give up their reception.

should not be consumed at the same time furadonin drugs affecting the acid-alkaline balance in the body. The drug has a less pronounced effect in the case of increasing the alkali content in the urine.

analogs

Using the original medicament is not always possible, so physicians can select analog having similar composition and therapeutic properties.

Medicament Features
furagin Antimicrobial wide spectrum of action. In the composition the active ingredient is present furazidin which relates to nitrofurans group. Available medication in tablet form, is indicated for the various forms of cystitis, urethritis and other pathologies of the urinary system. A special feature of this tool is considered the possibility of appointing the prostate, unlike furadonin that when such a violation does not apply.
FURAMAG Antimicrobial agent comprises furazidin as active substance. Vypskaetsya in capsule form, the dosage can be 25 or 50 mg. Prescribers in cystitis, pyelonephritis and urethritis. Can be used in mild prostatitis, some gynecological infections. The drug has much the same properties as furadonin, but is considered a softer, gentler and safer.
Furasol The preparation in powder form comprising potassium furazidin as an active component. It has a strong anti-microbial and anti-inflammatory effect. Used topically medicament after pre-dissolving the content package 1 in 300 ml of warm water. Tool is rarely used as a substitute for furadonin, but it helps to alleviate the patient's condition.
Furadonin cystitis. Instructions for use, price, reviews, analogues

Analogues of the drug be used only after consulting a doctor. Despite the similar composition and properties, they can trigger complications.

Terms, conditions of sale and storage

Shelf life funds is 4 years. date of manufacture can be seen on the packaging or in the manual. Store the medicament must be at a temperature not higher than +250FROM. It is recommended to prevent ingress of moisture in the packaging, direct sunlight.

It is important to keep the medication away from children. The drug pharmacy by prescription, but in many regions it is possible to get free.

Price in drugstores of Moscow, St. Petersburg, regions

The cost of medicines in the drugstores of Moscow and St. Petersburg is in the range of 70-130 rubles. per pack. Price depends on the dosage and the number of blisters in a box. In the regions, for example, in Taganrog, Voronezh and Belgorod tool can be bought for 60-100 rubles.

Reviews of the effectiveness of

Many patients reported that the medication very quickly improves the condition and prevent complications. That is why the feedback was mostly positive.

But many patients say that after taking a headache, nausea and other symptoms. Despite this, the active agent used in the treatment of patients of all ages.

Furadonin - a drug that is often used in cystitis and other urinary tract pathologies. Positive feedback from patients demonstrate its effectiveness. With proper application of the medicament does not lead to adverse reactions and complications.

Registration of the article: Vladimir the Great

Videos about furadonin

Reviews of doctors about the drug furadonin:

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