Detraleks is an effective drug that is often It is used for varicose legs, as well as other vascular diseases. Patients comments about the tool preferably positive, due to the rapid achievement of therapeutic response and the manifestation of adverse reactions rare.
The content of the article:
- 1 Shape and composition of the drug release
- 2 pharmacological properties
- 3 Pharmacodynamics and Pharmacokinetics
- 4 Indications
- 5 Contraindications
- 6 Instructions for use, the dosage of the drug in varicose veins on the legs
- 7 Exchange treatment detraleks
- 8 Side effects
- 9 Overdose
- 10 special instructions
- 11 drug interactions
- 12 analogs
- 13 Terms, conditions of sale and storage
- 14 Price in drugstores of Moscow, St. Petersburg, regions
- 15 Reviews of the effectiveness of
- 16 Videos about detraleks
Shape and composition of the drug release
The medication is available for purchase in the form of tablets that are film-coated and have a small size. They are packed in blisters of 15 pieces. The carton can be 2 or 4 blister. These necessarily attached instructions for use.
The dosage of each tablet is 500 mg. A larger amount of this dose, namely 90%, is given a substance that is called diosmin. The remaining 10% are represented component called hesperidin. Both components have strong therapeutic properties and are highly complementary.
Additionally, as part of the drug are present auxiliary ingredients:
- magnesium stearate.
- titanium dioxide.
- Sodium lauryl sulfate.
Optional components help keep the chemical composition of the tablets and to form the desired shape. It should be noted that the additional ingredients do not have therapeutic effects on the body.
Detraleks legs with varicose veins (patient reviews of this medicine mostly positive) is used quite often, since it has angioprotektornoy properties and normalises metabolic processes in the lower walls of the large vessels limbs. The main effect of treatment is observed from the veins.
Active ingredients stimulate recovery inner vessel walls, reduce their permeability and help prevent stretching of the muscular layer. The latter property is considered the most important because it prevents the pathological enlargement of blood vessels and poor circulation in the lower extremities.
In addition, the drug has the property of venous and stimulates regeneration of damaged vascular areas. Improvement in the area of the affected vein microcirculation to reduce the burden on them and facilitate the course of the disease.
Pharmacodynamics and Pharmacokinetics
The pharmaceutical agent starts to operate immediately after penetration into the patient. The main active component acts on leukocytes and inflammatory mediators that can prevent damage of the vascular wall. With this done slowing of disease progression.
Diosmin also stimulates the production of cells capable of restoring the integrity of the vessel walls when they are damaged. He additionally helps prevent tension veins when you receive a large amount of blood. Reduction of capillary permeability and large veins can prevent swelling of the limbs. This symptom often observed in varicose veins.
Due to the properties of venous increases elasticity of blood vessels, allowing them to return back into shape after stretching. Normalization of blood circulation leads to better nutrition of tissues, decreases the risk of venous ulcers on the skin of the feet.
The pharmacokinetics of the drug begins after ingestion. The tablet dissolves quickly in the digestive tract, where absorption of the active ingredients occurs. Diosmin and hesperidin quickly concentrated in the affected area, blocks the inflammatory mediators, has a therapeutic effect.
Processing of the active substances in the liver. Means only in small doses accumulate in the body and excreted within 24 hours after the last dose. The basic quantity is evacuated through the intestines, but about 14-15% yield via the kidneys.
Experts do not undertake research that would be able to show the ability of drugs to penetrate into breast milk and through the placenta, but there is a version that it is possible.
In patients with pathologies of the small and large intestines during the elimination is prolonged for 6-8 hours. Patients with problems in the kidneys may also be faced with such a problem. In chronic renal failure, the active ingredients may be evacuated from the body for 2 days.
Detraleks is not only used for varicose legs, but in other vascular pathology. Testimonials show that timely prescription medicines help to cope with the first manifestations of the many violations:
- Thrombophlebitis at the initial stage accompanied by mild symptoms.
- Swelling of the feet at the end of the working day or in the afternoon.
- Pain and heaviness in the lower extremities, which is manifested when wearing uncomfortable shoes.
- The appearance of spider veins on the legs of different sizes.
- Abnormal increase in limb volume for no apparent reason.
In these cases it is possible to use tablets, which help to improve the condition and prevent complications. The decision on the appointment of the drug takes only a doctor. In addition to injuries of the lower extremities, a drug used in the complex treatment of hemorrhoids and venous insufficiency.
Medication is effective and relatively safe, but its use is not always allowed. The main contraindication is considered to be an individual intolerance of any of the components comprising the means and inclination to allergic manifestations.
Do not use the medicine in advanced thrombophlebitis with the threat of separation of thrombus from the vessel wall and promote it to the bloodstream. Another contraindication to treatment is considered a severe form of kidney and liver failure.
This is due to the impossibility of recycling the components in the body with subsequent breeding. The tool is not indicated for severe lesions of the stomach and intestines, the propensity to bleeding.
Postoperatively Detraleks not apply. His appointment is permitted no earlier than 2 weeks after the intervention, especially in the case where it was held on the digestive system.
Medication is contraindicated during pregnancy and lactation, as well as under the age of 18 years. In each case the list of contraindications is made individually, taking into account the accompanying abnormalities of other organs.
Instructions for use, the dosage of the drug in varicose veins on the legs
Detraleks for varicose legs (ratings recommended study to study the effect of the agent) used by the standard procedure: the tablet is taken orally, washed down with water.
Better not chew them, as the film coating protects the active ingredients from premature dissolution, which should begin only in the stomach.
Dosage for patients with varicose veins is 1000 mg per day, ie 1 tablet in the afternoon and evening. To use means better while eating, which increases its efficiency and improves dissolution.
Sometimes patients with severe venous insufficiency, varicose veins and swelling strong prescribe 2 tablets 2 times a day, but the course is usually short.
During treatment tool is recommended to adhere to a special regime, that is, to eat and tablets around the same time. In the morning hours the drug is better not to use because it may slightly reduce blood pressure and makes the patient and sluggish inhibited.
Exchange treatment detraleks
In each case, the duration of use of the medicament may vary. It depends on the severity of symptoms and possible complications that often occur with varicose veins and similar pathologies. The usual short course lasts 2 weeks during which the patient is taking 2 tablets per day.
With the progression of the disease means the duration of use is at least 6 weeks. Patients with chronic and advanced forms of varicose veins may prescribe long courses of 3-5 months. The dosage of the drug thus should not exceed 1000 mg per day.
In appointing the drug long courses specialist examines the patient usually at least 1 time in 2 weeks to evaluate the effect of the drug and note improvement.
Many patients say that for 2-4 weeks, the effect of the use of tablets was observed. This is due to the gradual accumulation of active substances in the body. That is the first 2-4 weeks the result appears.
Detraleks for varicose legs (reviews of means predominantly positive) is used most often, because rarely provokes negative reactions in the internal organs.
However, complications can develop in violation of instructions:
- Headache and dizziness.
- Weakness, and sleep disturbance. In this case, the patient noted the changes at once, consider them a consequence of fatigue or nervous tension.
- Nausea and vomiting attacks, not related to food intake. The patient's condition after gastric emptying usually improves.
- Steady reduction in blood pressure indicators.
- Disorders of the gut, manifested in the form of liquid stool go obstipation.
Such manifestations are considered rare. Typically the medication is well tolerated. In patients with a tendency to allergies, may cause rashes on different parts of the body, arms and legs. In this case, severe itching and swelling of the skin is not observed, but the rash is still provokes discomfort.
An overdose of the drug is extremely rare, since the active ingredient in a small amount It accumulates in the body and quickly displayed in the absence of digestive pathologies and kidney.
But in the case of use of a large dose of the drug indicated increasing incidence of allergic reactions. Rash extends to extensive areas of skin, small pimples increase in size and filled with a transparent or turbid liquid. Patient notes increased itching, it affected area combs, which leads to the formation of surface weeping.
It is at this stage increases the likelihood of infection and adherence of skin inflammation. In addition to appearances, there are common disorders in the form of weakness, increase or decrease in blood pressure. Somewhat later joined watery eyes, symptoms of allergic rhinitis and nasal discharge, a large amount of clear mucus.
In exceptional cases, may develop angioedema, wherein the observed swelling of the mucous membranes and upper palate of the larynx, which leads to respiratory failure or even suffocation. In this case, the patient requires immediate medical attention, as the state threatens not only health, but also life.
Using the varices in patients with severe developmental complications can not replace a more radical methods of treatment. During treatment, experts recommend completely abandon drinking alcohol, since the products of ethanol disintegration adversely affect the body, especially on blood vessels and heart.
The doctors also insist on correction of the diet and daily regimen for patients who suffer from obesity or overweight. It is recommended to walk and to exclude from the menu of flour, confectionery products, fatty meats.
Patients with chronic venous insufficiency during treatment is recommended to wear compression stockings, which reduces the load on the affected vessels. This will get more pronounced therapeutic result.
The interaction of the drug with other medicines have not been conducted, but experts do not recommend using it in conjunction with potent antibiotics and hormonal drugs.
It should not be combined with other means venotonic medicines for oral administration. However, the simultaneous use of detraleks with venotoniki for external application brings good effect. Gels and ointments may only increase the effect of the agent.
Tablets are often used as part of a treatment of vascular drugs, such as pentoxifylline and its analogs. It should be noted that when using the drug with other groups, means there is no adverse reaction, but the doctors do not recommend self-medication combined.
Detraleks for varicose legs (reviews of the facility should be read prior to the therapeutic course) It is considered the most preferred treatment option, but in some cases it can not be use. There are several alternatives that have similar or different composition, but provide similar therapeutic effect.
|Antistax||The drug of natural origin, produced in the form of capsules for oral administration. As part of the agent is present, and the extract of red vine leaves, which has anti-edematous, and venous tonic properties. Due to this a reduction in vascular permeability, improving their walls and improving the general condition of the patient. The agent can not become a full-fledged substitute detraleks, but suitable for patients with an initial stage of varicose veins.|
|flebodia 600||A preparation in the form of tablets, which contains as active component diosmin. It is this medication often used instead detraleks. But experts say that the second is better absorbed in the body and its maximum concentration in the blood has reached 3 hours after ingestion. Flebodia is a pretty effective way and helps in easy and progressive stages of varicose veins.|
|troksevazin||Popular agent which is available in capsule form for oral administration and for topical application of the gel. Doctors recommend to use 2 forms of release to achieve a therapeutic effect. The composition contains troxerutin. The substance is expressed angioprotective, venotonic effect and strengthens blood vessels. The course of treatment involves taking money for 2-4 weeks and 1 capsule in the morning and evening. At the same time it is necessary twice a day to cover their skin with a thin layer of the lower limbs, to rub massage movements.|
Drug analogues used only after consulting a specialist. Absolutely contraindicated use their own medication.
Terms, conditions of sale and storage
The drug should be stored out of the reach of children and protected from moisture and direct sunlight. It is not necessary to store medication in the refrigerator.
Shelf life funds is 4 years, the date of manufacture indicated on the package. Buy tablets can be in the pharmacy without a prescription from a doctor.
Price in drugstores of Moscow, St. Petersburg, regions
The cost of medicines in the drugstores of Moscow and St. Petersburg is about 800 rubles. 30 units and about 1,600-1,700 rubles. 60 pieces. In Kursk, Voronezh and Rostov-on-Don tool can be purchased for 750 rubles. and 1500 rubles. depending on the number of tablets per pack.
Reviews of the effectiveness of
Detraleks considered quite effective medication for varicose legs, so often used. Reviews predominantly positive patients. Many patients say that the effect occurs within a few days after the start of the course.
But some patients say that the drug is not effective, and the cost is not justified. Despite this, the drug is widely used in the treatment of people of different sex and age.
Registration of the article: Vladimir the Great
Videos about detraleks
Doctors about detraleks: